Evaluation of cognitive function by Near-Infrared Spectroscopy

• Project/Area Number: 19700448
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Rehabilitation science/Welfare engineering
• Research Institution: Jikei University School of Medicine
• Principal Investigator: ASHIMOTO Keiji Jikei University School of Medicine, 第二専門診療部リハビリテーション科, 医長 (10376717)
• Project Period (FY): 2006 – 2009
• Project Status: Completed (Fiscal Year 2009)
• Budget Amount: ¥3,600,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥600,000); Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2008: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2007: ¥1,000,000 (Direct Cost: ¥1,000,000)
• Keywords: 高次脳機能障害 / 近赤外線分光法 / 脳血流 / リハビリテーション / びまん性軸索損傷 / 軽症脳外傷 / 拡散テンソル画像 / 高次脳機能 / 前頭葉機能 / 外傷性脳損傷

Research Abstract

To investigate brain activation in the prefrontal cortex (PFC) during the Wisconsin Card Sorting Test (Keio Version) (KWCST), we examined changes in total hemoglobin volume (THV) in 8 patients with traumatic brain injury (TBI) and 20 healthy control subjects using two-channel near-infrared spectroscopy. These results demonstrated that the TBI patients had lower circulation of hemoglobin in the right PFC during the KWCST than the control subjects.

Research Products

• [Journal Article] Brain scienceのトピックス.外傷性脳損傷:認知リハビリテーションの進歩. (2009)
  • Author(s): 橋本圭司
  • Journal Title: Jpn J Rehabil Med 46 Pages: 418-22
• [Journal Article] Activation of the prefrontal cortex during the KWCST as measured by 2-channel near-infrared spectroscopy in patients with traumatic brain injury. (2008)
  • Author(s): Hashimoto K, Uruma G, Abo M.
  • Journal Title: Eur Neurol 59 Pages: 24-30
• [Journal Article] of the prefrontal cortex during the KWCST as measured by 2-channel near-infrared spectroscopy in patients with traumatic brain injury. (2008)
  • Author(s): Hashimoto K, Uruma G, Abo M.
  • Journal Title: European Neurology 59 Pages: 24-30
  • Peer Reviewed
• [Presentation] DAIとMTBIの相違-DTIパラメーターを用いた診断支援システムの構築- (2008)
  • Author(s): 笠原和美, 橋本圭司・他
  • Organizer: 第36回日本磁気共鳴医学会大会
  • Place of Presentation: 旭川市文化会館
  • Year and Date: 2008-09-11
• [Presentation] シンポジウム「Brain scienceのトピックス」外傷性脳損傷:認知リハビリテーション (2008)
  • Author(s): 橋本圭司
  • Organizer: 第3回リハビリテーション科専門医会学術集会
  • Place of Presentation: 福岡
• [Book] 脳解剖から学べる高次脳機能障害リハビリテーション入門 (2009)
  • Author(s): 橋本圭司、上久保毅
  • Total Pages: 108
  • Publisher: 診断と治療社
• [Book] 高次脳機能を鍛える (2008)
  • Author(s): 橋本圭司
  • Publisher: 全日本病院出版会
• [Book] 高次脳機能を鍛える (2008)
  • Author(s): 橋本圭司
  • Total Pages: 65
  • Publisher: 全日本病院出版協会