| Budget Amount *help |
¥3,570,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥570,000)
Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2008: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2007: ¥1,100,000 (Direct Cost: ¥1,100,000)
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| Research Abstract |
Molecular mechanism for muscle hypertrophy in response to heat stress is still unclear. In the present study, the molecular responses of skeletal muscles to heat stress were investigated in experimental animals and cultured skeletal muscle cells. Results demonstrated that nuclear factor-Kβ signaling would be, in part, involved in heat-stress-associated skeletal muscle hypertrophy in vivo and in vitro. Therefore, it is strongly suggested that the application of heat stress to skeletal muscle might be a useful tool for an increase in muscle mass and force generation in elderly people.
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