Flexibility and arterial stiffness

• Project/Area Number: 19700552
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Applied health science
• Research Institution: Waseda University
• Principal Investigator: YAMAMOTO Kenta Waseda University, 先端科学・健康医療融合研究機構, 講師 (80434380)
• Project Period (FY): 2007 – 2008
• Project Status: Completed (Fiscal Year 2008)
• Budget Amount: ¥3,680,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥480,000); Fiscal Year 2008: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000); Fiscal Year 2007: ¥1,600,000 (Direct Cost: ¥1,600,000)
• Keywords: 生活習慣病 / 柔軟性 / 動脈硬化 / 体力

Research Abstract

本研究は、1)柔軟性と動脈硬化度との関係を、2)柔軟性と加齢に伴う動脈硬化との関係を検討した。その結果、横断研究から1)中高齢者において、体が硬い(柔軟性が低い)と血管も硬い(動脈硬化度が高い)こと、2)柔軟性が低いと加齢に伴う動脈の硬化が促進されること、縦断研究から3)柔軟性10cmの増加は血管年齢を約9歳若返らせる可能性が示唆された。

Research Products

• [Journal Article] Low-intensity resistance training with slow movement and tonic force generation increases basal limb blood flow (2009)
  • Author(s): Tanimoto M, Yamamoto K, et al
  • Journal Title: Clin Physiol Funct Imaging 29 Pages: 128-135
  • Peer Reviewed
• [Journal Article] Muscle mass and bone mineral indices: does the normalized bone mineral content differ with age (2009)
  • Author(s): Sanada K, Yamamoto K, et.al.
  • Journal Title: Eur J Clin Nutr (In press)
  • Peer Reviewed
• [Journal Article] Effects of whole-body low-intensity resistance training with slow movement and tonic force generation (LST) on muscular size and strength in young men (2009)
  • Author(s): Tanimoto M. Yamamoto K., et.al.
  • Journal Title: Journal of Strength and Conditioning Research 22(6) Pages: 1926-1938
  • Peer Reviewed
• [Journal Article] Low-intensity resistance training with slow movement and tonic force generation increases basal limb b lood flow (2009)
  • Author(s): Tanimoto M. Yamamoto K, et.al.
  • Journal Title: Clin Physiol Funct Imaging 29(2) Pages: 128-135
  • Peer Reviewed
• [Journal Article] Muscle mechanoreflex augments arterial baroreflex-mediated dynamic sympathetic response to carotid sinus pressure (2008)
  • Author(s): Yamamoto K, Kawada T, et al
  • Journal Title: Am J Physiol Heart Circ Physiol 295 Pages: 1081-1089
  • Peer Reviewed
• [Journal Article] Resistance training in men is associated with increased arterial stiffness and blood pressure but does not adversely affect endothelial function as measured by arterial reactivity to the cold pressor test (2008)
  • Author(s): Kawano H, Yamamoto K, et al
  • Journal Title: Exp Physiol 93 Pages: 296-302
  • Peer Reviewed
• [Journal Article] Muscle mass and bone mineral indices : does the normalized bone mineral content differ with age? (2008)
  • Author(s): Sanada K, Yamamoto K, et al
  • Journal Title: Eur J Clin Nutr
  • Peer Reviewed
• [Journal Article] Required muscle mass for preventing lifestyle-related diseases in Japanese women (2008)
  • Author(s): Miyatani M, Yamamoto K, et al
  • Journal Title: BMC Public Health 8 Pages: 291-291
  • Peer Reviewed
• [Journal Article] Effects of whole-body low-intensity resistance training with slow movement and tonic force generation (LST) on muscular size and strength in young men (2008)
  • Author(s): Tanimoto M, Yamamoto K et al
  • Journal Title: Journal of Strength and Conditioning Research 22(6) Pages: 1926-2938
  • Peer Reviewed
• [Journal Article] Muscle mechanoreflex augments arterial baroreflex-mediated dynamic sympathetic response to carotid sin us pressure (2008)
  • Author(s): Yamamoto K. Kawada T., et.al.
  • Journal Title: Am J Physiol Heart Ciro Physiol 295 (3)
  • Peer Reviewed
• [Journal Article] Required muscle mass for preventing lifestyle-related diseases in Japanese women (2008)
  • Author(s): Miyatani M, Yamamoto K, et.al.
  • Journal Title: BMC Public Health 8 Pages: 291-291
  • Peer Reviewed
• [Journal Article] Resistance training in men is associated with increased arterial stiffness and blood pressure but does not adversely affect endothelial function as measured by arterial reactivity... (2008)
  • Author(s): Kawano H, Yamamoto K, Miyachi M et al.
  • Journal Title: Exp Physiol 93 Pages: 296-302
  • Peer Reviewed
• [Journal Article] Nonexercise models for predicting maximal oxygen uptake existing physiological basis (2007)
  • Author(s): Sanada K, Yamamoto K, et al
  • Journal Title: Eur J Appl Physiol 101 Pages: 265-266
  • Peer Reviewed
• [Journal Article] Nonexercise models for predicting maximal oxygen uptake existing physiological basis (2007)
  • Author(s): Sanada K, Yamamoto K, Abe T et al.
  • Journal Title: Eur J Appl Physiol 101 Pages: 265-266
  • Peer Reviewed
• [Journal Article] Effects of whole-body low-intensity resistance training with slow movement and tonic force generation (LST) on muscular size and strength in young men.
  • Author(s): Tanimoto M., Sanada K., Yamamoto K., et al.
  • Journal Title: Journal of Strength and Conditioning Research (In p)
  • Peer Reviewed
• [Journal Article] Muscle Mass and Bone Mineral indices: Does the Normalised Bone Mineral Content Differ with Age?
  • Author(s): Sanada K., Yamamoto K., Higuchi M. et al.
  • Journal Title: Eur J Clin Nutr (In p)
  • Peer Reviewed
• [Presentation] Effects of Dietary Folate Intake and Physical Activity on The Interaction Between The Plasma Homocysteine and MTHFR Genotype (2008)
  • Author(s): HiltonHead, SouthCarolina. USA
  • Organizer: The Integrative Biology of Exercise V
  • Place of Presentation: Hilton Head. Southearolina, USA
  • Year and Date: 2008-09-27
• [Presentation] Interaction Between Flexibility and Cardiorespiratory Fitness on Arterial Stiffness (2008)
  • Author(s): Yamamoto K., Miyachi M., et.al.
  • Organizer: The Integrative Biology of Exercise V
  • Place of Presentation: Hilton Head, South Carolina, USA
  • Year and Date: 2008-09-25
• [Presentation] Physical Activity Estimated by Triaxial Accelerometer is An Independent Predictor of Arterial Stiffening (2008)
  • Author(s): Gando Y., Yamamoto K., et.al.
  • Organizer: The Integrative Biology of Exercise V
  • Place of Presentation: Hilton Head, South Carolina. USA
  • Year and Date: 2008-09-25
• [Presentation] Flexibility is fitness related to arterial stiffness (2008)
  • Author(s): Yamamoto K, Kawano H, et.al.
  • Organizer: JSPFSM-ECSS Exchange Symposium, 13th Annual Congress of the European College of Sport Science
  • Place of Presentation: Estoril. Portugal
  • Year and Date: 2008-07-12
• [Presentation] The PPAR gamma gene, cardiorespiratory fitness and metabolic syndrome in young and old Japanese men an d women (2008)
  • Author(s): Sanada K., Yamamoto K., et.al.
  • Organizer: 13th Annual Congress of the European College of Sport Science
  • Place of Presentation: Estoril, Portugal
  • Year and Date: 2008-07-11
• [Presentation] Reference values and prediction models of Sarcopenia in Japanese men and women (2008)
  • Author(s): Sanada K., Yamamoto K., et.al.
  • Organizer: 55th Annual Meeting of the American College of Sports Medicine
  • Place of Presentation: Indianapolis, USA
  • Year and Date: 2008-05-30
• [Presentation] Flexibility is fitness related to arterial stiffness (2008)
  • Author(s): Yamamoto K, Kawano H, et al
  • Organizer: JSPFSM-ECSS Exchange Symposium. In : 13th Annual Congress of the European College of Sport Science
  • Place of Presentation: Estoril -Portgal
• [Presentation] Interaction Between Flexibility and Cardiorespiratory Fitness on Arterial Stiffness (2008)
  • Author(s): Yamamoto K, Kawano H, et al
  • Organizer: The Integrative Biology of Exercise V
  • Place of Presentation: South Carolina, USA
• [Presentation] Physical Activity Estimated by Triaxial Accelerometer is An Independent Predictor of Arterial Stiffening (2008)
  • Author(s): Gando Y, Yamamoto K et al
  • Organizer: The Integrative Biology of Exercise V
  • Place of Presentation: South Carolina, USA
• [Presentation] Effects of Dietary Folate Intake and Physical Activity on The Interaction Between The Plasma Homocysteine and MTHFR Genotype (2008)
  • Author(s): Murakami H, Yamamoto K et al
  • Organizer: The Integrative Biology of Exercise V
  • Place of Presentation: South Carolina, USA
• [Presentation] The PPAR gamma gene, cardiorespiratory fitness and metabolic syndrome in young and old Japanese men and women (2008)
  • Author(s): Sanada K, Yamamoto K et al
  • Organizer: 13th Annual Congress of the European College of Sport Science
  • Place of Presentation: Estoril-Portgal
• [Presentation] Ventilatory threshold is associated with abdominal obesity and previous cardiovascular diseases in Japanese adults (2008)
  • Author(s): Sanada K, Yamamoto K et al
  • Organizer: 55th Annual Meeting of the American College of Sports Medicine
  • Place of Presentation: Indianapolis, USA
• [Presentation] 全身持久力、柔軟性および筋パワーと動脈硬化度との関係 (2008)
  • Author(s): 山元健太,河野寛ら
  • Organizer: 第63回日本体力医学会
  • Place of Presentation: 大分
• [Presentation] 血中ホモシステイン濃度とMTHFR遺伝子多型の関連に対する身体活動および葉酸摂取の影響 (2008)
  • Author(s): 村上晴香,山元健太ら
  • Organizer: 第63回日本体力医学会
  • Place of Presentation: 大分
• [Presentation] 中年女性を対象とした「サーキット式コンバインドトレーニング」の身体諸機能に与える影響 (2008)
  • Author(s): 谷本道哉,山元健太ら
  • Organizer: 第63回日本体力医学会
  • Place of Presentation: 大分
• [Presentation] 中心動脈の弾性機能に対する習慣的な漕艇練習の好ましい効果 (2008)
  • Author(s): 河野寛,山元健太ら
  • Organizer: 第16回日本運動生理学会
  • Place of Presentation: 奈良
• [Presentation] メタボリックシンドロームと体力との関係 (2008)
  • Author(s): 宮地元彦,山元健太ら
  • Organizer: 日本体育学会第59回大会
  • Place of Presentation: 東京
• [Presentation] 日本人成人男女を対象としたサルコペニア評価基準および簡易評価法の開発 (2008)
  • Author(s): 真田樹義,山元健太ら
  • Organizer: 日本体育学会第59回大会
  • Place of Presentation: 東京
• [Presentation] 筋発揮張力維持法(LST)を用いた筋カトレーニングが四肢血流量に与える影響 (2007)
  • Author(s): 谷本道哉, 山元健太, 宮地元彦
  • Organizer: 第62回日本体力医学会
  • Place of Presentation: 秋田
  • Year and Date: 2007-09-15
• [Presentation] Contribution Of Obese-Related Genes And Cardiorespiratory fitness To The Metabolic Syndrome In Middle-Aged Aan Old Men And Women (2007)
  • Author(s): Sanada K, Yamamoto K, Higuchi M. et al.
  • Organizer: 12th Anual Congress of the European College of Sport Science
  • Place of Presentation: Jyvaskyla
  • Year and Date: 2007-07-14
• [Presentation] Effects Of Whole Body Low-Intensity Resistance Trainning program With Slow (Movement And Tonic Force Generation (LST) On Muscular Function In Young Men (2007)
  • Author(s): Tanimoto M, Yamamoto K, Miyachi M. et al.
  • Organizer: 12th Annual Congress of the European College of Sport Science
  • Place of Presentation: Jyvaskvla
  • Year and Date: 2007-07-13
• [Presentation] Greater Age-related Arterial Stiffening and Left Ventricular Hypertrophy in Poor Cardiorespiratory Fitness Women (2007)
  • Author(s): Gando Y, Yamamoto K, Higuchi M. et al.
  • Organizer: 54th Annual Meeting of the American College of Snorts Medicine
  • Place of Presentation: New Orleans
  • Year and Date: 2007-05-30
• [Presentation] Poor Flexibility is associated with Arterial Stiffening (2007)
  • Author(s): Yamamoto K, Kawano H et al
  • Organizer: 54th Annual Meeting of the American College of Sports Medicine
  • Place of Presentation: New Orleans
• [Presentation] Greater Age-related Arterial Stiffening and Left Ventricular Hypertrophy in Poor Cardiorespiratory Fitness Women (2007)
  • Author(s): Gando Y, Yamamoto K et al
  • Organizer: 54th Annual Meeting of the American College of Sports Medicine
  • Place of Presentation: New Orleans
• [Presentation] Age, flexibility, and metabolic syndrome (2007)
  • Author(s): Miyachi M, Yamamoto K et al
  • Organizer: 54th Annual Meeting of the American College of Sports Medicine
  • Place of Presentation: New Orleans
• [Presentation] Fitness and the Predisposition to Metabolic Syndrome in Japanese Men and Women (2007)
  • Author(s): Sanada K, Yamamoto K et al
  • Organizer: 54th Annual Meeting of the American College of Sports Medicine
  • Place of Presentation: New Orleans
• [Presentation] Carotid Artery Vasoreactivity To Cold Presser Teat In Resistance-Trained Men (2007)
  • Author(s): Kawano H, Yamamoto K et al
  • Organizer: 12th Annual Congress of the European College of Sport Science
  • Place of Presentation: Jyvaskyla
• [Presentation] Contribution Of Obese-Related Genes And Cardiorespiratory fitness To The Metabolic Syndrome In Middle-Aged Aan Old Men And Women (2007)
  • Author(s): Sanada K, Yamamoto K et al
  • Organizer: 12th Annual Congress of the European College of Sport Science
  • Place of Presentation: Jyvaskyla
• [Presentation] Effects Of Whole Body Low-Intensity Resistance Trainning program With Slow Movement And Tonic Force Generation (LST) On Muscular Function In Young Men (2007)
  • Author(s): Tanimoto M, Yamamoto K et al
  • Organizer: 12th Annual Congress of the European College of Sport Science
  • Place of Presentation: Jyvaskyla
• [Presentation] 動脈圧受容器反射と筋機械受容器反射の相互作用のモデル化.「運動時の末梢循環調節」 (2007)
  • Author(s): 山元健太
  • Organizer: 運動と循環研究会
  • Place of Presentation: 東京
• [Presentation] 体の柔軟性は動脈硬化と関連する (2007)
  • Author(s): 山元健太,河野寛ら
  • Organizer: 第62回日本体力医学会
  • Place of Presentation: 秋田
• [Presentation] 筋力トレーニング者における局所的寒冷刺激に対する頸動脈径の反応性 (2007)
  • Author(s): 河野寛,山元健太ら
  • Organizer: 第62回日本体力医学会
  • Place of Presentation: 秋田
• [Presentation] 心肺体力の高い女性では加齢による動脈硬化と左心室肥大が抑制される (2007)
  • Author(s): 丸藤祐子,山元健太ら
  • Organizer: 第62回日本体力医学会
  • Place of Presentation: 秋田
• [Presentation] 中高年男女を対象とした肥満関連遺伝子、身体組成、有酸素能力とメタボリックシンドロームとの関係 (2007)
  • Author(s): 真田樹義,山元健太ら
  • Organizer: 第62回日本体力医学会
  • Place of Presentation: 秋田
• [Presentation] 筋発揮張力維持法(LST)を用いた筋力トレーニングが四肢血流量に与える影響 (2007)
  • Author(s): 谷本道哉,山元健太ら
  • Organizer: 第62回日本体力医学会
  • Place of Presentation: 秋田