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Manipulation of dietary essential fatty acid balance for lifestyle-related disease prevention

Research Project

Project/Area Number 19700587
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Eating habits, studies on eating habits
Research InstitutionAkita University

Principal Investigator

IKEMOTO Atsushi  Akita University, 教育文化学部, 准教授 (60295615)

Project Period (FY) 2007 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥3,710,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥510,000)
Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2008: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2007: ¥1,500,000 (Direct Cost: ¥1,500,000)
Keywordsリノール酸 / α-リノレン酸 / ドコサヘキサエン酸 / エイコサペンタエン酸 / 脂肪細胞 / 骨芽細胞 / 筋芽細胞 / メタボリック症候群 / n-3系列脂肪酸 / n-6系列脂肪酸 / インスリン / 間葉系幹細胞 / 食事バランスガイド / 脂質バランスガイド / アラキドン酸 / 筋細胞 / 分化 / メタボリック症候 / メダボリック症候
Research Abstract

We investigated the effect of dietary essential fatty acid balance (n-6/n-3) on lifestyle-related diseases. N-3 fatty acids suppressed adipogenesis whereas they promoted both myoblast and osteoblast differentiation. Dietary n-3 fatty acid such as fish oil has been shown to decrease serum triglyceride, cholesterol and insulin levels and abdominal fat weight but increase muscle weight in the mice. These results demonstrate that the increased intake of n-3 fatty acid has preventive effects on metabolic syndrome. On the basis of the results, we made Lipid Balance Guide and used it in the class of junior high school. The guide was a useful educational tool for understanding of lipid nutrition.

Report

(4 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • 2007 Annual Research Report
  • Research Products

    (20 results)

All 2009 2008 2007

All Journal Article (8 results) (of which Peer Reviewed: 8 results) Presentation (9 results) Patent(Industrial Property Rights) (3 results)

  • [Journal Article] 多価不飽和脂肪酸が間葉系幹細胞の分化に及ぼす影響2009

    • Author(s)
      池本敦、福田希、大山詩香
    • Journal Title

      脂質栄養学 18巻

      Pages: 171-179

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] 多価不飽和脂肪酸が間葉系幹細胞の分化に及ぼす影響2009

    • Author(s)
      池本敦、福田希、大山詩香
    • Journal Title

      脂質栄養学 18

      Pages: 171-179

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Synaptic vesicle-associated glycolytic ATP-generating enzymes: coupling to neurotransmitter accumulation2008

    • Author(s)
      Tetsufumi Ueda, Atsushi Ikemoto
    • Journal Title

      Integration of Moleccular and cellular Processes 3巻

      Pages: 241-259

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Synaptic vesicle-associated glycolytic ATP-generating enzymes : coupling to neurotransmitter accumulation2008

    • Author(s)
      Tetsufumi Ueda, Atsushi Ikemoto
    • Journal Title

      Handbook of Neurochemistry And Molecular Neurobioloav 3

      Pages: 241-259

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 過去と将来の長期的展望2007

    • Author(s)
      William E.M. Lands、池本敦、脂質栄養
    • Journal Title

      脂質栄養学 16巻

      Pages: 9-19

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] 精白米の脂質含量及び脂肪酸組成の品種による相違と食事脂質バランスに及ぼす影響2007

    • Author(s)
      池本敦、長沼誠子
    • Journal Title

      秋田大学教育文化学部研究紀要(自然科学) 62巻

      Pages: 19-28

    • NAID

      110006224982

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] 精白米の脂質含量及び脂肪酸組成の品種による相違と食事脂質バランスに及ぼす影響2007

    • Author(s)
      池本, 敦・長沼, 誠子
    • Journal Title

      秋田大学教育文化学部研究紀要(自然科学) 62

      Pages: 19-28

    • NAID

      110006224982

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 脂質栄養:過去と将来の長期的展望2007

    • Author(s)
      William, E.・M., Lands・池本, 敦
    • Journal Title

      脂質栄養学 16

      Pages: 9-19

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Presentation] 学校教育における脂質栄養と食事バランスガイドの改善に関する提案2009

    • Author(s)
      中村美穂、池本敦
    • Organizer
      日本脂質栄養学会第18回大会
    • Place of Presentation
      コクヨ会館(東京都)
    • Year and Date
      2009-09-06
    • Related Report
      2009 Final Research Report
  • [Presentation] アケビ果皮抽出物による高脂肪食誘導肥満の抑制2009

    • Author(s)
      佐藤謙太、池本敦
    • Organizer
      日本脂質栄養学会第18回大会
    • Place of Presentation
      コクヨ会館(東京都)
    • Year and Date
      2009-09-06
    • Related Report
      2009 Final Research Report
  • [Presentation] 学校教育における脂質栄養と食事バランスガイドの改善に関する提案2009

    • Author(s)
      中村美穂、池本敦
    • Organizer
      日本脂質栄養学会第18回大会
    • Place of Presentation
      東京
    • Year and Date
      2009-09-06
    • Related Report
      2009 Annual Research Report
  • [Presentation] アケビ果皮抽出物による高脂肪食誘導肥満の抑制2009

    • Author(s)
      佐藤謙太、池本敦
    • Organizer
      日本脂質栄養学会第18回大会
    • Place of Presentation
      東京
    • Year and Date
      2009-09-06
    • Related Report
      2009 Annual Research Report
  • [Presentation] 多価不飽和脂肪酸が間葉系幹細胞の分化に及ぼす影響2009

    • Author(s)
      池本敦、福田希、大山詩香
    • Organizer
      日本脂質栄養学会第18回大会
    • Place of Presentation
      コクヨ会館(東京都)
    • Year and Date
      2009-09-05
    • Related Report
      2009 Final Research Report
  • [Presentation] 多価不飽和脂肪酸が間葉系幹細胞の分化に及ぼす影響2009

    • Author(s)
      池本敦、福田希、大山詩香
    • Organizer
      日本脂質栄養学会第18回大会
    • Place of Presentation
      東京
    • Year and Date
      2009-09-05
    • Related Report
      2009 Annual Research Report
  • [Presentation] アセチル基含有脂質の栄養学的特性:アケビ油と他の油脂との比較2008

    • Author(s)
      池本敦、佐藤謙太、藤井ゆみ
    • Organizer
      日本脂質栄養学会第17回大会
    • Place of Presentation
      大阪国際会議場(大阪市)
    • Year and Date
      2008-09-05
    • Related Report
      2009 Final Research Report
  • [Presentation] アセチル基含有脂質の栄養学的特性 : アケビ油と他の油脂との比較2008

    • Author(s)
      池本敦、佐藤謙太、藤井ゆみ
    • Organizer
      日本脂質栄養学会第17回大会
    • Place of Presentation
      大阪市・大阪国際会議場
    • Year and Date
      2008-09-05
    • Related Report
      2008 Annual Research Report
  • [Presentation] アセチル基含有脂質を主成分とするアケビ種子抽出油脂の代謝特性2007

    • Author(s)
      池本敦、藤井ゆみ
    • Organizer
      日本脂質栄養学会第16回大会
    • Place of Presentation
      ウェルシティ島根(出雲市)
    • Year and Date
      2007-09-01
    • Related Report
      2009 Final Research Report 2007 Annual Research Report
  • [Patent(Industrial Property Rights)] 高脂血症及び肥満の予防改善用組成物2009

    • Inventor(s)
      池本敦、坂本賢二
    • Industrial Property Rights Holder
      秋田大学、(株)坂本バイオ
    • Industrial Property Number
      2009-115489
    • Filing Date
      2009-05-12
    • Related Report
      2009 Final Research Report
  • [Patent(Industrial Property Rights)] 高脂血症及び肥満の予防改善用組成物2009

    • Inventor(s)
      池本敦, 坂本賢二
    • Industrial Property Rights Holder
      秋田大学坂本バイオ
    • Industrial Property Number
      2009-115489
    • Filing Date
      2009-05-12
    • Related Report
      2009 Annual Research Report
  • [Patent(Industrial Property Rights)] 高脂血症及び肥満の予防改善用組成物2009

    • Inventor(s)
      池本敦
    • Industrial Property Rights Holder
      秋田大学
    • Industrial Property Number
      2009-115489
    • Filing Date
      2009-05-12
    • Related Report
      2008 Annual Research Report

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Published: 2007-04-01   Modified: 2016-04-21  

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