Function of essential fatty acids on the brain development, formulation and sustainment.
Project/Area Number |
19700603
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Single-year Grants |
Research Field |
Eating habits, studies on eating habits
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Research Institution | Kinjo Gakuin University |
Principal Investigator |
MIYAZAWA Daisuke Kinjo Gakuin University, 薬学部, 助教 (70434553)
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Project Period (FY) |
2007 – 2008
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Project Status |
Completed (Fiscal Year 2008)
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Budget Amount *help |
¥2,010,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥210,000)
Fiscal Year 2008: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2007: ¥1,100,000 (Direct Cost: ¥1,100,000)
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Keywords | 栄養学 / 細胞・組織 / 脂質 / 神経科学 / 脳・神経 |
Research Abstract |
ICRマウス(雄、5週齢)に高リノール酸ベニバナ油(High-LA)或いは高α-リノレン酸シソ油(High-ALA)を5%添加した精製飼料を4週間与えた。大脳皮質、線条体のドコサヘキサエン酸(DHA)はHigh-LA群に対しHigh-ALA群が有意に高かった。BDNF量を測定したところ、線条体ではHigh-LA群に対し、High-ALA群で有意に高かった。p38MAPK活性は線条体ではHigh-LA群に対し、High-ALA群で有意に高かった。
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Report
(3 results)
Research Products
(16 results)
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[Journal Article] Hepatocyte growth factor promotes endogenous repair and functional recovery after spinal cord injury2007
Author(s)
Kitamura K., Iwanami A., Nakamura M., Yamane J., Watanabe K., Suzuki Y., Miyazawa D., Shibata S., Funakoshi H., Miyatake S., Coffin R. S, Nakamura T., Toyama Y. and Okano H.
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Journal Title
J. Neurosci. Res. 85
Pages: 2332-2342
Related Report
Peer Reviewed
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