Contamination level and risk assessment of polycyclic aromatic hydrocarbons and their derivatives

• Project/Area Number: 19710030
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Environmental impact assessment/Environmental policy
• Research Institution: Setsunan University
• Principal Investigator: TERUYUKI Nakao Setsunan University, 薬学部薬学科, 助手 (20288971)
• Project Period (FY): 2007 – 2008
• Project Status: Completed (Fiscal Year 2008)
• Budget Amount: ¥2,630,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥330,000); Fiscal Year 2008: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2007: ¥1,200,000 (Direct Cost: ¥1,200,000)
• Keywords: 陸圏 / 水圏 / 大気圏影響評価 / 環境分析 / 大気汚染防止・浄化 / 有害化学物質 / 衛生 / 環境 / 多環芳香族炭化水素 / 高毒性 / 燃焼 / 多環芳香族炭化水素(PAHs) / メチル化PAHs / ニトロ化PAHs / アリルハイロドロカーボンレセプター / 交差反応性 / 環境大気

Research Abstract

高分離能ガスクロマトグラフィー・高分解能マススペクトロメトリー(HRGC-HRMS)および蛍光検出・器付高速液体クロマトグラフィー(FL-HPLC)を駆使し、環境大気や廃棄物焼却施設から排出されるPAHおよびその高毒性誘導体の発生実態を解明した。また、これら有害化学物質のAhレセプター反応性を明らかにした。

Research Products

• [Journal Article] Global contamination of coplana polybrominated/chlorinated biphenyls (Co-PXBs) in the market fishes from Japan (2008)
  • Author(s): S.Ohta, T.Nakao, O.Aozasa, H.Miyata, et,al
  • Journal Title: Chemosphere 73 Pages: 31-38
  • Peer Reviewed
• [Journal Article] PCB Contamination Assessment of Yusho Patients by Using Preserved Human Umbilica lCord (2008)
  • Author(s): O.Aozasa, T.Nakao, S.Ohta, H,Miyata, et.al
  • Journal Title: Environ, Contam. Toxcol 81 Pages: 578-582
  • Peer Reviewed
• [Journal Article] Global contamination of coplanar polybrominated/chlorinated biphenyls (Co-PXBs) in the market fishes from Japan (2008)
  • Author(s): S. Ohta, T. Nakao, et.al.
  • Journal Title: Chemosphere 73
  • Peer Reviewed
• [Journal Article] PCB Contamination Assessment of Yusho Patients by Using Preserved Human Umbilical Cord (2008)
  • Author(s): O. Aozasa, T. Nakao, et.al.
  • Journal Title: Bull. Environ. Contam. Toxicol 81 Pages: 578-582
  • Peer Reviewed
• [Journal Article] Analytical method for determination of dinitropyrenes using gas chromat Qgraphy-high-resolution masss pectrometry (2007)
  • Author(s): T.Nakao, O.Aozasa, S.Ohta, H,Miyata
  • Journal Title: J.ChromatographyA 1157 Pages: 352-357
  • Peer Reviewed
• [Journal Article] Analytical method for determination of dinitropyrenes using gaschromatography-high-resolution mass spectrometry (2007)
  • Author(s): T. Nakao, et. al
  • Journal Title: Journal of Chromatography A 1157 Pages: 352-357
  • Peer Reviewed
• [Presentation] Determination of Co-Planar Polybrominated-chlorinated Biphenyls in Fish from Great Lakes : Preliminary Results and Analytical Challenges (2008)
  • Author(s): T Nakao, S. Ohta
  • Organizer: 28th International symposium on halogenated persistent organic pollutants (POPs)
  • Place of Presentation: Birmingham England UK
  • Year and Date: 2008-08-21
• [Presentation] Investigation of Simple Evaluation Method of Air Pollution by Brominated Environmental Pollutants using Japanese Black Pine Needle as an Indicator (The first report) (2008)
  • Author(s): H. Miyata, T. Nakao, O. Aozasa, S. Ohta
  • Organizer: 28th International symposium on halogenated persistent organic pollutants (POPs)
  • Place of Presentation: Birmingham England UK
  • Year and Date: 2008-08-19
• [Presentation] Determination of Co-Planar Polybrominatedlchlorinated Biphenyls in Human Breast Milk from Twenty Woman of JAPAN (2008)
  • Author(s): S. Ohta, T. Nakao, O. Aozasa, H. Miyata
  • Organizer: 28th International symposium on halogenated persistent organic pollutants (POPs)
  • Place of Presentation: Birmingham England UK
  • Year and Date: 2008-08-18
• [Presentation] Determination of co-planar polybrominated/chlorinated biphenyls in fish from Great lakes : Preliminary results and analytical challenges (2008)
  • Author(s): S. Ohta, T. Nakao, et.al.
  • Organizer: Organohalogen compounds
  • Place of Presentation: Birmingham, UK
  • Year and Date: 2008-08-18
• [Presentation] Determination of co-planar polybrominated/chlorinated biphenyls in human breast milk from twenty woman of Japan (2008)
  • Author(s): S. Ohta, T. Nakao, et.al.
  • Organizer: Organohalogen compounds
  • Place of Presentation: Birmingham, UK
  • Year and Date: 2008-08-18
• [Presentation] Investigation of simple evaluation method of air pollution by brominated environmental pollutants using Japanese black pine needle as an indicator (The first report) (2008)
  • Author(s): H. Miyata, T. Nakao, et.al.
  • Organizer: Organohalogen compounds
  • Place of Presentation: Birmingham, UK
  • Year and Date: 2008-08-18
• [Presentation] 黒松研葉を評価試料としたハロゲン化環境汚染物質の大気濃度評価法の構築 (2008)
  • Author(s): 中尾晃幸, ら
  • Organizer: 日本環境化学会
  • Place of Presentation: 神戸国際会議場
  • Year and Date: 2008-06-12
• [Presentation] AhRC PCRTMによる微量有害化学物質のAhR交差反応性 (2008)
  • Author(s): 中尾晃幸, ら
  • Organizer: 日本環境化学会
  • Place of Presentation: 神戸国際会議場
  • Year and Date: 2008-06-12
• [Presentation] ダイオキシン高感受性C57BL/6マウスにおける臭素化ダイオキシン類の毒性評価 (2008)
  • Author(s): 中尾晃幸, ら
  • Organizer: 日本環境化学会
  • Place of Presentation: 神戸国際会議場
  • Year and Date: 2008-06-12
• [Presentation] 飛灰試料を用いたダイオキシン類のクロスチェック (2008)
  • Author(s): 宮田秀明、中尾晃幸、青笹治、太田壮一
  • Organizer: 第17回環境化学討論会
  • Place of Presentation: 神戸国際会議場(神戸市)
  • Year and Date: 2008-06-11
• [Presentation] 日本の母乳中のCo-PXBs汚染を主としたダイオキシン類による汚染実態の解明 (2008)
  • Author(s): 太田壮一、中尾晃幸、青笹治、宮田秀明
  • Organizer: 第17回環境化学討論会
  • Place of Presentation: 神戸国際会議場(神戸市)
  • Year and Date: 2008-06-11
• [Presentation] 黒松針葉を評価試料としたハロゲン化環境汚染物質の大気濃度評価法の構築 (2008)
  • Author(s): 宮田秀明、中尾晃幸、青笹治、太田壮一
  • Organizer: 第17回環境化学討論会
  • Place of Presentation: 神戸国際会議場(神戸市)
  • Year and Date: 2008-06-11
• [Presentation] AhRCPCRTMによる微量有害化学物質のAhR交差反応性 (2008)
  • Author(s): 中尾晃幸、青笹治、太田壮一、宮田秀明
  • Organizer: 第17回環境化学討論会
  • Place of Presentation: 神戸国際会議場(神戸市)
  • Year and Date: 2008-06-11
• [Presentation] ダイオキシン高感受性C57BL/6マウスにおけイオキシン類の毒性評価 (2008)
  • Author(s): 青笹治、中尾晃幸、宮田秀明、太田壮一
  • Organizer: 第17回環境化学討論会
  • Place of Presentation: 神戸国際会議場(神戸市)
  • Year and Date: 2008-06-11
• [Presentation] 飛灰試料を用いたダイオキシン類のクロスチェック (2008)
  • Author(s): 中尾晃幸, ら
  • Organizer: 日本環境化学会
  • Place of Presentation: 神戸国際会議場
  • Year and Date: 2008-06-11
• [Presentation] 日本の母乳中のCo-PXBs汚染を主としたダイオキシン類による汚染実態の解明 (2008)
  • Author(s): 中尾晃幸, ら
  • Organizer: 日本環境化学会
  • Place of Presentation: 神戸国際会議場
  • Year and Date: 2008-06-11
• [Presentation] Investigation of the main source of halogenated environmental pollutants in human breast milk (The fourth report)-Influence by fast- (2007)
  • Author(s): H. Miyata, T. Nakao, 0. Aozasa, S. Ohta
  • Organizer: 27th International symposium on halogenated persistent organic pollutants (POPs)
  • Place of Presentation: Tokyo, Japan
  • Year and Date: 2007-09-03
• [Presentation] Contamination levels of polychlorintaed/brominated coplanar biphenyls (Co-PXBs) in the market foods and mother's milk of Japan (2007)
  • Author(s): S. Ohta, T. Nakao, 0. Aozasa, H. Miyata
  • Organizer: 27th International symposium on halogenated persistent organic pollutants (POPs)
  • Place of Presentation: Tokyo, Japan
  • Year and Date: 2007-09-03
• [Presentation] Investigation about cross-check result of dioxin analogues using a fish sample prepared by Cambridge Isotope Laboratories INC (2007)
  • Author(s): H. Miyata, T. Nakao, 0. Aozasa, S. Ohta
  • Organizer: 27th International symposium on halogenated persistent organic pollutants (POPs)
  • Place of Presentation: Tokyo, Japan
  • Year and Date: 2007-09-03
• [Presentation] 大気中の多環芳香族炭化水素およびその誘導体の汚染について (2007)
  • Author(s): 中尾 晃幸ら
  • Organizer: 第16回環境化学討論会
  • Place of Presentation: 北九州国際会議場
  • Year and Date: 2007-06-21
• [Presentation] 魚試料を用いたダイオキシン類のクロスチェック (2007)
  • Author(s): 宮田秀明、中尾晃幸、青笹治、太田壮一
  • Organizer: 第16回環境化学討論会
  • Place of Presentation: 北九州国際会議場(北九州市)
  • Year and Date: 2007-06-20
• [Presentation] カネミ油症患者における保存さい帯(へその緒)中のPCB濃度(第2報) (2007)
  • Author(s): 青笹治、中尾晃幸、宮田秀明、太田壮一
  • Organizer: 第16回環境化学討論会
  • Place of Presentation: 北九州国際会議場(北九州市)
  • Year and Date: 2007-06-20
• [Presentation] 大気中の多環芳香族炭化水素およびその誘導体の汚染について (2007)
  • Author(s): 中尾晃幸、宮田秀明、青笹治、太田壮一
  • Organizer: 第16回環境化学討論会
  • Place of Presentation: 北九州国際会議場(北九州市)
  • Year and Date: 2007-06-20
• [Presentation] 輸入魚試料を用いた新規環境汚染物質Co-PXBによる海洋汚染実態 (2007)
  • Author(s): 太田壮一、中尾晃幸、青笹治、宮田秀明
  • Organizer: 第16回環境化学討論会
  • Place of Presentation: 北九州国際会議場(北九州市)
  • Year and Date: 2007-06-20
• [Presentation] 日本の母乳中の塩素・臭素化ダイオキシン類(PXDDs/DFs,Co-PXBs)による汚染実態の解明 (2007)
  • Author(s): 太田壮一、中尾晃幸、青笹治、宮田秀明
  • Organizer: 第16回環境化学討論会
  • Place of Presentation: 北九州国際会議場(北九州市)
  • Year and Date: 2007-06-20
• [Presentation] 母乳中ハロゲン化環境汚染物質の主な汚染源の究明(第3報)-食事摂取と絶食による影響- (2007)
  • Author(s): 宮田秀明、中尾晃幸、青笹治、太田壮一
  • Organizer: 第16回環境化学討論会
  • Place of Presentation: 北九州国際会議場(北九州市)
  • Year and Date: 2007-06-20