Dielectrophoretic patterning with different cell types and its electrochemical estimation

• Project/Area Number: 19710112
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Microdevices/Nanodevices
• Research Institution: University of Hyogo
• Principal Investigator: TOMOYUKI Yasukawa University of Hyogo, 大学院・物質理学研究科, 准教授 (40361167)
• Project Period (FY): 2007 – 2008
• Project Status: Completed (Fiscal Year 2008)
• Budget Amount: ¥3,720,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥420,000); Fiscal Year 2008: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000); Fiscal Year 2007: ¥1,900,000 (Direct Cost: ¥1,900,000)
• Keywords: 誘電泳動 / 電気化学顕微鏡 / 微粒子配列 / 細胞配列 / グルコースセンサ / 単一細胞 / 酵素センサ / 酸素選択的透過膜

Research Abstract

誘電泳動を用いて迅速,簡便に細胞をパターニングできるデバイスを開発した.連続的に異種類の細胞を導入し,交流電圧の印加パターンを変化させることにより,1枚の基板上に違う種類の細胞を交互に配列することができた.マイクロ電極の先端に酸素選択的透過膜およびグルコースオキシダーゼを固定化することにより,細胞評価が可能なマイクログルコースセンサを作製できた.

Research Products

• [Journal Article] Rapid Fabrication of Nanoparticles Array on Polycarbonate Membrane Based on Positive Dielectrophoresis (2008)
  • Author(s): H. J. Lee, T. Yasukawa, M. Suzuki, Y. Taki, A. Tanaka, M. Kameyama, H. Shiku, T. Matsue
  • Journal Title: Sensors and Actuators B: Chemical 131(2) Pages: 424-431
  • Peer Reviewed
• [Journal Article] Electrophoretic cell manipulation and electrochemical gene-function analysis based on a yeast two-hybrid system in a microfluidic device (2008)
  • Author(s): T. Yasukawa, K. Nagamine, Y. Horiguchi, H. Shiku, M. Koide, T. Itayama, F. Shiraishi, T. Matsue
  • Journal Title: Anal. Chem 80(10) Pages: 3722-3727
  • Peer Reviewed
• [Journal Article] Cell-Based Electrochemical Assay for Endotoxin Using a Secreted Alkaline Phosphatase Reporter System (2008)
  • Author(s): K. Y. Inoue, T. Yasukawa, H. Shiku, T. Matsue
  • Journal Title: Electrochemistry 76(8) Pages: 525-528
  • NAID: 130002150721
  • Peer Reviewed
• [Journal Article] Enzyme immunoassay of insulin at picomolar levels based on the coulometric determination of hydrogen peroxide (2008)
  • Author(s): F. Mizutani, E. Ohta, Y. Mie, O. Niwa, T. Yasukawa
  • Journal Title: Sensors and Actuators, B: Chemical 135 (1) Pages: 304-308
  • Peer Reviewed
• [Journal Article] Rapid and separation-free sandwich immunosensing based on accumulation of microbeads by negative dielectrophoresis (2008)
  • Author(s): H. J. Lee, T. Yasukawa, H. Shiku, T. Matsue
  • Journal Title: Biosens. Bioelectron 24 Pages: 1006-1011
  • Peer Reviewed
• [Journal Article] Rapid Fabrication of Nanoparticles Array on Polycarbonate Membrane Based on Positive Dielectronhoresis (2008)
  • Author(s): Hyun Jung Lee, et.al.
  • Journal Title: Sensors and Actuators B : Chemical 131 Pages: 424-431
  • Peer Reviewed
• [Journal Article] Electrophoretic cell manipulation and electrochemical gene-function analysis based on ayeast two-hybrid system in a microfluidic device (2008)
  • Author(s): Tomoyuki Yasukawa, et.al.
  • Journal Title: Anal. Chem 80 Pages: 3722-3727
  • Peer Reviewed
• [Journal Article] Negative dielectrophoretic patterning with two different cell types (2008)
  • Author(s): Masato Suzuki, et.al.
  • Journal Title: Biosens. Bioelectron 24 Pages: 1049-1053
  • Peer Reviewed
• [Journal Article] Cell-Based Electrochemical Assay for Endotoxin Using a Secreted Alkaline Phosphatase Reporter System (2008)
  • Author(s): Kumi Y. Inoue, et.al.
  • Journal Title: Electrochemistry 76 Pages: 525-528
  • Peer Reviewed
• [Journal Article] Enzyme immunoassay of insulin at picomolar levels based on the coulometric determination of hydrogen peroxide (2008)
  • Author(s): Fumio Mizutani, et.al.
  • Journal Title: Sensors and Actuators, B : Chemical 135 Pages: 304-308
  • Peer Reviewed
• [Journal Article] Rapid and separation-free sandwich immunosensing based on accumulation of microbeads by negative dielectrophoresis (2008)
  • Author(s): Hyun Jung Lee, et.al.
  • Journal Title: Biosens. Bioelectron 24 Pages: 1006-1011
  • Peer Reviewed
• [Journal Article] バイオチップの走査型電気顕微鏡解析 (2008)
  • Author(s): 安川智之, ら
  • Journal Title: 表面技術 59 Pages: 818-824
• [Journal Article] Rapid Fabrication of Nanoparticles Array on Polycarbonate Membrane Based on Positive Dielectrophoresis (2008)
  • Author(s): Hyun Jung Lee, et. al.
  • Journal Title: Sensors and Actuators B:Chemical 131 Pages: 424-431
  • Peer Reviewed
• [Journal Article] Flow sandwich-type immunoassay in microfluidic devices based on negative dielectrophoresis (2007)
  • Author(s): T. Yasukawa, M. Suzuki, T. Sekiya, H. Shiku, T. Matsue
  • Journal Title: Biosens. Bioelectron. 22 Pages: 2730-2736
  • Peer Reviewed
• [Journal Article] A multicellular spheroid array to realize spheroid formation, culture, and viability assay on a chip (2007)
  • Author(s): Y. Torisawa, A. Takagi, Y. Nashimoto, T. Yasukawa, H. Shiku, T. Matsue
  • Journal Title: Biomaterials 28 Pages: 559-566
  • Peer Reviewed
• [Journal Article] Electrochemical screening of recombinant protein solubility in Escherichia coli using scanning electrochemical microscopy (SECM) (2007)
  • Author(s): K. Nagamine, S. Onodera, A. Kurihara, T. Yasukawa, H. Shiku, R. Asano, I. Kumagai, T. Matsue
  • Journal Title: Biotechnology and bioengineering 96(5) Pages: 1008-1013
  • Peer Reviewed
• [Journal Article] Patterning and Encapsulation with Colloidal Particles into Hydrogel using Negative-Dielectrophoretic Method (2007)
  • Author(s): M. Suzuki, T. Yasukawa, H. Shiku, T. Matsue
  • Journal Title: Langmuir 23(7) Pages: 4088-4094
  • Peer Reviewed
• [Journal Article] Enzyme Immunosensing of Pepsinogens 1 and 2 by Scanning Electrochemical Microscopy, Biosens (2007)
  • Author(s): T. Yasukawa, Y. Hirano, N. Motochi, H. Shiku, T. Matsue
  • Journal Title: Bioelectron 22(12) Pages: 3099-3104
  • Peer Reviewed
• [Journal Article] A Competitive Immunochromatographic Assay for Testosterone Based on Electrochemical Detection (2007)
  • Author(s): K. Inoue, P. Ferrante, Y. Hirano, T. Yasukawa, H. Shiku, T. Matsue
  • Journal Title: alanta 73 Pages: 886-892
  • Peer Reviewed
• [Journal Article] Measurement of gene expression from single adherent cells and spheroids collected using fast electrical lysis (2007)
  • Author(s): Nashimoto, Y., Takahashi, Y., Yamakawa, T., Torisawa, Y.-S., Yasukawa, T., Ito-Sasaki, T., Yokoo, M., Abe, H., Shiku, H., Kambara, H., Matsue, T.
  • Journal Title: Analytical Chemistry 79(17) Pages: 6823-6830
  • Peer Reviewed
• [Journal Article] Microfluidic chip integrated with amperometric detector array for in situ estimating oxygen consumption characteristics of single bovine embryos (2007)
  • Author(s): Wu, C.-C., Saito, T., Yasukawa, T., Shiku, H., Abe, H., Hoshi, H., Matsue, T.
  • Journal Title: Sensors and Actuators, B : Chemical 125(2) Pages: 680-687
  • Peer Reviewed
• [Journal Article] Regulation and characterization of the polarity of cells embedded in a reconstructed basement matrix using a three-dimensional micro-culture system (2007)
  • Author(s): Torisawa, Y.-S., Nashimoto, Y., Yasukawa, T., Shiku, H., Matsue, T.
  • Journal Title: Biotechnology and Bioengineering 97(3) Pages: 615-621
  • Peer Reviewed
• [Journal Article] Microcontact printed diaphorase monolayer on glass characterized by atomic force microscopy and scanning electrochemical microscopy (2007)
  • Author(s): H. Q. Luo, H. Shiku, A. Kumagai, Y. Takahashi, T. Yasukawa, T. Matsue
  • Journal Title: Electrochemistry Communications 9(11) Pages: 2703-2708
  • Peer Reviewed
• [Journal Article] Negative dielectrophoretic patterning with two different cell types, (2007)
  • Author(s): M. Suzuki, T. Yasukawa, H. Shiku, T. Matsue
  • Journal Title: Biosens. Bioelectron. 24 Pages: 1049-1053
  • Peer Reviewed
• [Journal Article] Flow sandwich-type immunoassay in microfluidic devices based on negative dielectrophoresis (2007)
  • Author(s): Tomoyuki Yasukawa, et. al.
  • Journal Title: Biosens. Bioeiectron. 22 Pages: 2730-2736
  • Peer Reviewed
• [Journal Article] A multicellular spheroid array to realize spheroid formation,cuiture,and viability assay on a chip (2007)
  • Author(s): Yusuke Torisawa, et. al.
  • Journal Title: Biomaterials 28 Pages: 559-566
  • Peer Reviewed
• [Journal Article] Electrochemical screening of recombinant protein solubility in Escherichia coli using scanning electrochemical microscopy(SECM) (2007)
  • Author(s): Kuniaki Nagamine, et. al.
  • Journal Title: Biotechnology and bioengineering 96 Pages: 1008-1013
  • Peer Reviewed
• [Journal Article] Patterning and Encapsulation with Colloidal Particles into Hydrogel using Negative-Dielectrophoretic Method (2007)
  • Author(s): Masato Suzuki, et. al.
  • Journal Title: Langmuir 23 Pages: 4088-4094
  • Peer Reviewed
• [Journal Article] Enzyme Immunosensing of Pepsinogens 1 and 2 by Scanning Electrochemical Microscopy (2007)
  • Author(s): Tomoyuki Yasukawa, et. al.
  • Journal Title: Biosens.Bioelectron. 22 Pages: 3099-3104
  • Peer Reviewed
• [Journal Article] A Competitive Immunochromatographic Assay for Testosterone Based on Electrochemical Detection (2007)
  • Author(s): Kumi lnoue, et. al.
  • Journal Title: Talanta 73 Pages: 886-892
  • Peer Reviewed
• [Presentation] 電荷蓄積法を利用した高感度N^1, N^<12>-ジアセチルスペルミン計測 (2009)
  • Author(s): 安川智之
  • Organizer: 電気化学会第76回大会
  • Place of Presentation: 京都大学
  • Year and Date: 2009-03-30
• [Presentation] 酸素選択的透過膜を搭載したグルコースセンサの開発 (2009)
  • Author(s): 安川智之
  • Organizer: 表面技術協会第119講演大会
  • Place of Presentation: 山梨大学
  • Year and Date: 2009-03-18
• [Presentation] 誘電泳動による微粒子配列制御と競合免疫法への応用 (2009)
  • Author(s): 安川智之
  • Organizer: マルチスケール操作によるシステム細胞工学 (バイオ操作) 第7回公開シンポジウム
  • Place of Presentation: 仙台
  • Year and Date: 2009-03-06
• [Presentation] 酸素濃度制御型マイクログルコースセンサの開発 (2009)
  • Author(s): 安川智之
  • Organizer: 日本分析化学会第57年会
  • Place of Presentation: 福岡大学
• [Presentation] Rapid immunosensing based on microparticle manipulation by negative dielectrophoresis (2008)
  • Author(s): T. Yasukawa, J. Ramon-Azcon, H. Shiku, F. Mizutani, T. Matsue,
  • Organizer: IUMRS-ICA
  • Year and Date: 2008-12-10
• [Presentation] RAPID IMMUNOSENSING BASED ON MICROPARTICLE MANIPULATION BY NEGATIVE DIELECTROPHORESIS (2008)
  • Author(s): T. Yasukawa, et.al.
  • Organizer: IUMRS-ICA 2008
  • Place of Presentation: Nagoya
  • Year and Date: 2008-12-10
• [Presentation] Negative dielectrophoretic manipulation with microparticles for rapid immunosensing (2008)
  • Author(s): T. Yasukawa, J. Ramon-Azcon, H. Shiku, F. Mizutani, T. Matsue,
  • Organizer: MHS2008, Nagoya University
  • Year and Date: 2008-11-08
• [Presentation] Negative dielectronhoretic maninulation with micronarticles for rapid immunosensing (2008)
  • Author(s): T. Yasukawa, et.al.
  • Organizer: MHS2008
  • Place of Presentation: Nagoya University
  • Year and Date: 2008-11-08
• [Presentation] 電荷蓄積型過酸化水素センサをプラットラォームとずる尿中腫瘍マーカーの高感度検出 (2008)
  • Author(s): 安川智之
  • Organizer: 第46回化学センサ研究発表会
  • Place of Presentation: 沖縄
  • Year and Date: 2008-09-04
• [Presentation] 誘電泳動を用いる微粒子操作技術の免疫測定への応用,実環境計測・診断システム協議会 表面・界面研究会講演会-電気化学の新展開と表面・界面 (2008)
  • Author(s): 安川智之
  • Organizer: 産業技術総合研究所九州センター
  • Year and Date: 2008-07-30
• [Presentation] 誘電泳動を用いる微粒子操作技術の免疫測定への応用 (2008)
  • Author(s): 安川智之
  • Organizer: 実環境計測・診断システム協議会表面・界面研究会講演会
  • Place of Presentation: 産業技術総合研究所九州センター
  • Year and Date: 2008-07-30
• [Presentation] Electrochemical Immunochromatographic Assay of Testosterone using Nitrocellulose Membrane (2008)
  • Author(s): T. Yasukawa, et.al.
  • Organizer: 12th International Meeting on Chemical Sensors
  • Place of Presentation: Columbus
  • Year and Date: 2008-07-14
• [Presentation] 誘電泳動を用いる迅速な免疫測定 (2008)
  • Author(s): 安川智之
  • Organizer: マルチスケール操作によるシステム細胞工学 (バイオ操作), 若手研究者第3回ワークショップ
  • Place of Presentation: 沖縄県那覇市テンブスホール
  • Year and Date: 2008-07-11
• [Presentation] 誘電泳動を用いる迅速な免疫測定 (2008)
  • Author(s): 安川智之
  • Organizer: マルチスケール操作によるシステム細胞工学 (バイオ操作) 第6回公開シンポジウム
  • Place of Presentation: キャンパスプラザ京都
  • Year and Date: 2008-06-13
• [Presentation] 細胞操作技術と電気化学法を融合した単-細胞計測 (2008)
  • Author(s): 安川智之
  • Organizer: 第17回環境化学討論会
  • Place of Presentation: 神戸国際会議場
  • Year and Date: 2008-06-11
• [Presentation] 誘電泳動を利用した細胞配列と免疫測定 (2008)
  • Author(s): 安川智之
  • Organizer: (社)表面技術協会第24回『ナノテク部会』研究会
  • Place of Presentation: 東京理科大学
  • Year and Date: 2008-05-13
• [Presentation] 誘電泳動を利用した細胞配列と免疫測定 (2008)
  • Author(s): 安川智之
  • Organizer: (社) 表面技術協会第24回『ナノテク部会』研究会
  • Place of Presentation: 東京理科大学(依頼講演)
  • Year and Date: 2008-05-13
• [Presentation] イニファータ重合法を用いるフェロセン誘導体の固定化と電気化学的特性の評価 (2008)
  • Author(s): 安川 智之
  • Organizer: 電気化学会第75回春季大会
  • Place of Presentation: 山梨大学(甲府)
  • Year and Date: 2008-03-30
• [Presentation] マイクログルコースセンサをプローブとした電気化学顕微鏡の開発 (2008)
  • Author(s): 安川 智之
  • Organizer: 表面技術協会第117回講演大会
  • Place of Presentation: 日本大学(千葉)
  • Year and Date: 2008-03-12
• [Presentation] 3次元グリッド電極を用いる細胞の一括電気回転 (2008)
  • Author(s): 安川 智之
  • Organizer: 特定領域「バイオ操作」第5回公開シンポジウム
  • Place of Presentation: 法政大学(東京)
  • Year and Date: 2008-03-07
• [Presentation] イクログルコースセンサをプローブとした電気化学顕微鏡の開発 (2008)
  • Author(s): 安川智之,水谷文雄
  • Organizer: 第117回講演大会
  • Place of Presentation: 日本大学
• [Presentation] Electrochemical Immunochromatographic Assay of Testosterone using Nitrocellulose Membrane (2008)
  • Author(s): T. Yasukawa, K. Inoue, P. Ferrante,Yu Hirano, H. Shiku, F. Mizutani, T. Matsue
  • Organizer: 12th International Meeting on Chemical Sensors (Columbus)
• [Presentation] 酸素濃度制御型マイクログルコースセンサの開発 (2008)
  • Author(s): 安川智之,吉村友希,吉本有希,後藤圭佑,水谷文雄
  • Organizer: 日本分析化学会第57年会
  • Place of Presentation: 福岡大学
• [Presentation] Mizutani, Enzyme Immunoassay for Insulin Using Highly-Sensitive Hydrogen Peroxide Sensors Based on Charge Accumulation Systems (2008)
  • Author(s): T. Yasukawa, E. Ohta, Y. Mie, O. Niwa, F.
  • Organizer: 214th ECS Meeting
  • Place of Presentation: Honolulu, HI
• [Presentation] 電荷蓄積型過酸化水素検出によるインスリンの高感度免疫計測 (2008)
  • Author(s): 安川智之
  • Organizer: 第69回分析化学討論会
  • Place of Presentation: 名古屋国際会議場
• [Presentation] Enzyme Immunoassay for Insulin Using Highly-Sensitive Hydrogen Peroxide Sensors Based on Charge Accumulation Systems (2008)
  • Author(s): T. Yasukawa, et.al.
  • Organizer: 214th ECS Meeting
  • Place of Presentation: Honolulu
• [Presentation] Patterning with different cell types based on the negative dielectrophoresis (2007)
  • Author(s): Tomoyuki Yasukawa
  • Organizer: 第18回日本MRS学術シンポジウム
  • Place of Presentation: 日本大学(東京)
  • Year and Date: 2007-12-08
• [Presentation] Matsue, Micropatterning with different cell types by dielectrophoretic manipulation (2007)
  • Author(s): T. Yasukawa, M. Suzuki, H. Shiku, T.
  • Organizer: MHS2007 & Micro-Nano COE@ Nagoya University
  • Year and Date: 2007-11-12
• [Presentation] Micropatterning with different cell types by dielectrophoretic manipulation (2007)
  • Author(s): Tomoyuki Yasukawa
  • Organizer: MHS2007 & Micro-Nano COE
  • Place of Presentation: Nagoya University(Nagoya)
  • Year and Date: 2007-11-12
• [Presentation] 誘電泳動による細胞配列および電気化学顕微鏡による活性評価 (2007)
  • Author(s): 安川智之,村田達哉,珠玖仁,末永智一
  • Organizer: 第16回化学とマイクロナノシステム研究会
  • Place of Presentation: つくば
  • Year and Date: 2007-10-30
• [Presentation] 誘電泳動による細胞配列および電気化学顕微鏡による活性評価 (2007)
  • Author(s): 安川 智之
  • Organizer: 第16回化学とマイクロナノシステム研究会
  • Place of Presentation: 産業技術総合研究所(つくば)
  • Year and Date: 2007-10-30
• [Presentation] 流路内における細胞操作と酵母Two-hybrid法を利用した遺伝子機能評価 (2007)
  • Author(s): 安川 智之
  • Organizer: 第10回 バイオテクノロジー部会シンポジウム
  • Place of Presentation: 早稲田大学(東京)
  • Year and Date: 2007-09-05
• [Presentation] 誘電泳動を用いる細胞アレイの作製とバイオセンサーヘの応用 (2007)
  • Author(s): 安川 智之
  • Organizer: 第1回化学センサー・バイオセンサーおよび計測技術合同ワークショップ
  • Place of Presentation: 慶応大学(横浜)
  • Year and Date: 2007-07-13
• [Presentation] 3次元マイクロアレイ電極システムを用いる細胞のドット配列および電気回転 (2007)
  • Author(s): 安川智之,鈴木雅登,珠玖仁,末永智一
  • Organizer: 第15回化学とマイクロナノシステム研究会
  • Place of Presentation: 東北大学
  • Year and Date: 2007-05-26
• [Presentation] 3次元マイクロアレイ電極システムを用いる細胞のドット配列および電気回転 (2007)
  • Author(s): 安川 智之
  • Organizer: 第15回化学とマイクロナノシステム研究会
  • Place of Presentation: 東北大学(仙台)
  • Year and Date: 2007-05-26
• [Presentation] 誘電泳動を応用した筋組織および神経筋接合部の組織再生工学 (2007)
  • Author(s): 安川 智之
  • Organizer: 特定領域「バイオ操作」若手研究者第1回ワークショップ
  • Place of Presentation: 京都
  • Year and Date: 2007-05-18
• [Presentation] 誘電泳動現象に基づく細胞操作技術の開発 (2007)
  • Author(s): 安川 智之
  • Organizer: 第2回東北大学多元物質材料研究所若手講演会
  • Place of Presentation: 東北大学(仙台)
  • Year and Date: 2007-05-15
• [Presentation] Mizutani, Patterning with different cell types based on the negative dielectrophoresis (2007)
  • Author(s): T.Yasukawa, M. Suzuki, T. Matsue, F
  • Organizer: 18th MRS-J Academic Symposium
  • Place of Presentation: 日本大学
• [Book] "Whole-cell biosensors", in Bioelectrochemistry : fundamentals, experimental techniques, and applications, Chapter 7, John Wiley & Sons Ltd. (2008)
  • Author(s): H. Shiku, K. Nagamine, T. Kaya, T. Yasukawa, T. Matsue
  • Publisher: West Sussex, UK. (Eds. P.N. Bartlett)
• [Book] 細胞分離・操作技術の最前線,第III編第2章誘電泳動による微粒子および細胞配列 (2008)
  • Author(s): 安川智之,鈴木雅登,末永智一
  • Publisher: シーエムシー出版
• [Book] バイオ電気化学の実際-バイオセンサ・バイオ電池の実用展開-実用編-バイオセンサ,第13章生体物質の局所分析と電気化学イメージング (2007)
  • Author(s): 高橋康史,安川智之,珠玖 仁,末永智一
  • Publisher: シーエムシー出版
• [Book] マイクロフルーイディックシステムを用いた細胞デバイス,バイオセンサ・ケミカルセンサ事典,第3編微小(マイクロ)アナリシスシステム,第2章(μTAS)(787-797) (2007)
  • Author(s): 鳥澤勇介,安川智之,珠玖仁,末永智一,
  • Publisher: テクノシステム
• [Book] バイオ電気化学の実際 -バイオセンサーバイオ電池の実用展開- 実用編-バイオセンサ (2007)
  • Author(s): 高橋 康史
  • Total Pages: 21
  • Publisher: シーエムシー出版
• [Remarks]
  • URL: http://www.sci.u-hyogo.ac.jp/material/analytical_chem/index-j.htm
• [Remarks]
  • URL: http://www.sci.u-hyogo.ac.jp/material/analytical_chem/index-j.html
• [Remarks]
  • URL: http://www.sci.u-hyogo.ac.jp/material/analytical_chem/index-j.html
• [Patent(Industrial Property Rights)] 電気化学測定装置の製造方法 (2008)
  • Inventor(s): 板山朋聡,小出昌弘,末永智一,安川智之,長峯邦明,珠玖仁
  • Industrial Property Rights Holder: 独立行政法人国立環境研究所
  • Industrial Property Number: 2008-012608
  • Filing Date: 2008-01-23
• [Patent(Industrial Property Rights)] 電気化学測定装置 (2008)
  • Inventor(s): 末永智一,林振宇,高橋康史,北川雄介,梅村太三,安川智之,国方亮太,珠玖仁
  • Industrial Property Rights Holder: 国立大学法人東北大学
  • Industrial Property Number: 2008-175120
  • Filing Date: 2008-07-03
• [Patent(Industrial Property Rights)] 電気化学測定装置 (2008)
  • Inventor(s): 末永智一, ら
  • Industrial Property Rights Holder: 国立大学法人東北大学
  • Filing Date: 2008-07-03
• [Patent(Industrial Property Rights)] 細胞のパターニング方
  • Inventor(s): 発明者:安川智之,鈴木雅登,珠玖仁,堀義生,稲垣明子,駒林真理子,末永智一
  • Industrial Property Rights Holder: 国立大学法人東北大学
  • Industrial Property Number: 2008-528802