Synthesis of Single-handed Helical Polymers from Racemic Monomers with Enzymes and Their Application

• Project/Area Number: 19750090
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Polymer chemistry
• Research Institution: Kinki University
• Principal Investigator: MORINO Kazuhide Kinki University, 分子工学研究所, 講師 (00362286)
• Project Period (FY): 2007 – 2008
• Project Status: Completed (Fiscal Year 2008)
• Budget Amount: ¥3,630,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥330,000); Fiscal Year 2008: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2007: ¥2,200,000 (Direct Cost: ¥2,200,000)
• Keywords: 高分子合成 / らせん / 光学活性 / キラル / 酵素 / ヨウ化サマリウム / 速度論的光学分割

Research Abstract

一分子内にビニル基とアルデヒド基を有する4-(ビニルベンジルオキシ)ベンズアルデヒドの二価のヨウ化サマリウム(SmI2)を用いた還元的カップリングにより、ビニル基を一分子内に二つ有するジオール化合物を合成することに成功した.この化合物は、二つのビニル基を有しているので、この点を利用して、ジチオールとのラジカル付加重合による主鎖中にキラルなジオール部位を有する高分子の合成や架橋剤としての応用、OH 基の修飾による機能性モノマーへの展開等が期待される.

Research Products

• [Journal Article] Helix Formation of Poly(phenylacetylene)s Bearing Azide Groups through Click Polymer Reaction with Optically Active Acetylenes (2009)
  • Author(s): S. Kobayashi, K. Itomi, K. Morino, H. Iida, and E. Yashima
  • Journal Title: Polym. J 41 Pages: 108-109
  • NAID: 10025090534
  • Peer Reviewed
• [Journal Article] Helix Formation of Poly(phenylacetylene)s Bearing Azide Groups through Click Polymer Reaction with Optically Active Acetylenes (2009)
  • Author(s): Ken Itomi
  • Journal Title: Polymer Journal 41 Pages: 108-109
  • Peer Reviewed
• [Journal Article] Polymerization of an optically active phenylacetylene derivative bearing an azide residue by click reaction and reaction with a rhodium catalyst (2008)
  • Author(s): S. Kobayashi, K. Itomi, K. Morino, H. Iida, and E. Yashima
  • Journal Title: Chem. Commun Pages: 3019-3021
  • Peer Reviewed
• [Journal Article] Synthesis and Helix Formation of Poly(m-phenylene) Bearing Optically Active Oligo(ethylene oxide) Side Chains in Protic Media (2008)
  • Author(s): T. Ben, H. Goto, K. Miwa, H. Goto, K. Morino, Y. Furusho, and E
  • Journal Title: Yashima, Macromolecules 41 Pages: 4506-4509
  • Peer Reviewed
• [Journal Article] Synthesis and Chiroptical Properties of a Helical Poly(phenylacetylene) Bearing Optically Active Pyrene Pendants (2008)
  • Author(s): H. Lin, K. Morino, and and E
  • Journal Title: Yashima, Chirality 20 Pages: 386-392
  • Peer Reviewed
• [Journal Article] Synthesis and Helix Formation of Poly(m-phenylene)s Bearing Optically Active Oligo(ethylene oxide) Side Chains in Protic Media (2008)
  • Author(s): Teng Beng
  • Journal Title: Macromolecules 41 Pages: 4506-4509
  • Peer Reviewed
• [Journal Article] Polymerization of an optically active phenylacetylene derivative bearing an azide residue by click reaction and reaction with a rhodium catalyst (2008)
  • Author(s): Shinzo Kobayashi
  • Journal Title: Chemical Communications Pages: 3019-3021
  • Peer Reviewed
• [Journal Article] Synthesis and Chiroptical Properties of a Helical Poly(phenylacetylene) Bearing Optically Active Pyrene Pendants (2008)
  • Author(s): H. Lin
  • Journal Title: Chirality 20 Pages: 386-392
  • Peer Reviewed
• [Journal Article] Synthesis of Optically Active Helical Poly(phenylacetylene)s Bearing Oligopeptide Pendants and Their Use as Polymeric Organocatalysts for Asymmetric Epoxidation (2007)
  • Author(s): K. Maeda, T. Tanaka, K. Morino, and E. Yashima
  • Journal Title: Macromolecules 40 Pages: 6783-6785
  • Peer Reviewed
• [Journal Article] Synthesis of Optically Active Helical Poly(phenylacetylene)s Bearing Oligopeptide Pendants and Their Use as Polymeric Organocatalysts for Asymmetric Epoxidation (2007)
  • Author(s): K. Tanaka
  • Journal Title: Macromolecules 40 Pages: 6783-6785
  • Peer Reviewed
• [Presentation] ポリ((4-カルボキシフェニル)アセチレン)に誘起されたらせん構造の記憶とその転写 (2007)
  • Author(s): 森野一英
  • Organizer: 第56回高分子学会年次大会
  • Place of Presentation: 京都国際会議場
  • Year and Date: 2007-05-31
• [Presentation] ポリ((4-カルボキシフェニル)アセチレン)に誘起されたらせん構造の記憶とその転写 (2007)
  • Author(s): 森野 一英
  • Organizer: 第56回高分子学会年次大会
  • Place of Presentation: 国立京都国際会館
  • Year and Date: 2007-05-31