Development of crystallization kinetic models based on multiphase flow simulation in an industrial crystallizer

• Project/Area Number: 19760112
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Fluid engineering
• Research Institution: Yokohama National University
• Principal Investigator: MISUMI Ryuta Yokohama National University, 大学院・工学研究院, 特別研究教員 (40334635)
• Project Period (FY): 2007 – 2009
• Project Status: Completed (Fiscal Year 2009)
• Budget Amount: ¥3,610,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥510,000); Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2008: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2007: ¥1,400,000 (Direct Cost: ¥1,400,000)
• Keywords: 撹拌 / 晶析 / CFD / 乱流 / 結晶摩耗 / 核発生 / 固液混相流 / Crystallization / crystallization / 乱流現象 / 製薬工業

Research Abstract

Attrition of crystal particles is one of the most significant phenomena to operate a crystallizer stably. On this subject we performed the Lagrangian simulation of crystal particles motion and particles collision on obstacles in a stirred vessel. Results clarified the effects of impeller rotational speeds on the particle impact, showing that the particle impact energy imparted on the loading faces of impeller blades and baffles was greater than that on the vessel walls.

Research Products

• [Journal Article] Suspension Property of Highly Concentrated Solid Particles Settling in a Draft-Tube Stirred Vessel (2008)
  • Author(s): R. Misumi, M. Tsukada, K. Nishi, M. Kaminoyama
  • Journal Title: Draft-Tube Stirred Vessel, J. Chem. Eng. Japan 41 Pages: 939-946
  • NAID: 10024340064
  • Peer Reviewed
• [Journal Article] Suspension Property of Highly Concentrated Solid Particles Settling in a Draft-Tube Stirred Vessel (2008)
  • Author(s): R. Misumi, M. Tsukada, K. Nishi, M. Kaminoyama
  • Journal Title: J. Chem. Eng. Japan 41 Pages: 939-946
  • NAID: 10024340064
  • Peer Reviewed
• [Presentation] 食塩の高濃度連続式蒸発晶析槽における製品結晶に及ぼす翼回転数と懸濁濃度の影響 (2010)
  • Author(s): 加藤慎平、三角隆太, ほか
  • Organizer: 化学工学会第75年会
  • Place of Presentation: 鹿児島大学
  • Year and Date: 2010-03-18
• [Presentation] 撹拌型晶析槽における結晶粒子と装置間の衝突による結晶摩耗現象の数値解析 (2010)
  • Author(s): 枡井康広、三角隆太, ほか
  • Organizer: 化学工学会第75年会
  • Place of Presentation: 鹿児島大学
  • Year and Date: 2010-03-18
• [Presentation] 撹拌型晶析槽における結晶粒子と装置是の衝突による結晶摩耗現象の数値解析 (2010)
  • Author(s): 枡井康広
  • Organizer: 化学工学会第75年会
  • Place of Presentation: 鹿児島大学
  • Year and Date: 2010-03-18
• [Presentation] 撹拌型晶析槽内の結晶粒子衝突に及ぼす翼形状の影響の検討 (2009)
  • Author(s): 佐々木拓二、三角隆太, ほか
  • Organizer: 化学工学会第41回秋季大会
  • Place of Presentation: 広島大学
  • Year and Date: 2009-09-16
• [Presentation] Lagrangian Numerical Simulation of Particle Collision and Suspension in a Stirred Vessel (2009)
  • Author(s): R. Misumi, et al.
  • Organizer: 8th World Congress of Chemical Engineering
  • Place of Presentation: Montreal (Canada)
  • Year and Date: 2009-08-26
• [Presentation] LAGRANGIAN NUMERICAL SIMULATION OF PARTICLE COLLISION AND SUSPENSION IN A STIRRED VESSEL (2009)
  • Author(s): Ryuta Misumi
  • Organizer: 8th World Congress of Chemical Engineering
  • Place of Presentation: Montreal (Canada)
  • Year and Date: 2009-08-26
• [Presentation] Lagrangian Numerical Simulation of Crystal Particle Impact in a Stirred Vessel (2008)
  • Author(s): R. Misumi, et al.
  • Organizer: 2nd Asian Conference on Mixing
  • Place of Presentation: Yonezawa (Japan)
  • Year and Date: 2008-10-07
• [Presentation] Development of Non-Intrusive Measurement Method of Primary Nucleation Phenomena in a Stirred Vessel Based on Laser Light Scattering (2008)
  • Author(s): R. Misumi, et al.
  • Organizer: 2nd Asian Conference on Mixing
  • Place of Presentation: Yonezawa (Japan)
  • Year and Date: 2008-10-07
• [Presentation] Development of Non-Intrusive Measurement Method of Primary Nucleation Phenomena in a Stirred Vessel Based on Laser. Light Scattering (2008)
  • Author(s): Ryuta MISUMI
  • Organizer: 2nd Asian Conference on Mixing
  • Place of Presentation: Yonezawa (JAPAN)
  • Year and Date: 2008-10-07
• [Presentation] Lagrangian Numerical Simulation of Crystal Particle Impact in a Stirred Vessel (2008)
  • Author(s): Ryuta MISUMI
  • Organizer: 2nd Asian Conference on Mixing
  • Place of Presentation: Yonezawa (JAPAN)
  • Year and Date: 2008-10-07
• [Presentation] レーザー散乱光計測を用いたグリシンの回分晶析における一次核発生挙動のその場計測 (2008)
  • Author(s): 加藤慎平、三角隆太, ほか
  • Organizer: 化学工学会第40回秋季大会
  • Place of Presentation: 東北大学
  • Year and Date: 2008-09-24
• [Presentation] ドラフトチューブ付撹拌型蒸発晶析槽における高効率操作条件の検討 (2008)
  • Author(s): 三角隆太, ほか
  • Organizer: 化学工学会第40回秋季大会
  • Place of Presentation: 東北大学
  • Year and Date: 2008-09-24
• [Presentation] ドラフトチューブ付撹拌型蒸発晶析槽における高効率操作条件の検討 (2008)
  • Author(s): 三角隆太
  • Organizer: 化学工学会第40回秋季大会
  • Place of Presentation: 東北大学(仙台)
  • Year and Date: 2008-09-24
• [Presentation] レーザー散乱光計測を用いたグリシンの回分晶析における一次核発生挙動のその場計測 (2008)
  • Author(s): 加藤慎平
  • Organizer: 化学工学会第40回秋季大会
  • Place of Presentation: 東北大学(仙台)
  • Year and Date: 2008-09-24
• [Presentation] Optimal seeding condition of a high suspension concentration of NaCl evaporative crystallization in a draft-tube stirred vessel (2008)
  • Author(s): R. Misumi, et al.
  • Organizer: 17th International Symposium on Industrial Crystallization
  • Place of Presentation: Maastricht (the Netherlands)
  • Year and Date: 2008-09-16
• [Presentation] 固液撹拌槽内での粒子衝突現象のラグラジアン解析 (2008)
  • Author(s): 三角隆太, ほか
  • Organizer: 日本流体力学会年会2008
  • Place of Presentation: 神戸大学
  • Year and Date: 2008-09-04
• [Presentation] 固液撹拌槽内での粒子衝突現象のラグラジアン解析 (2008)
  • Author(s): 三角隆太
  • Organizer: 日本流体力学会年会2008
  • Place of Presentation: 神戸大学(神戸)
  • Year and Date: 2008-09-04
• [Presentation] 三角隆太ほか、半回分式撹拌型食塩蒸発晶析装置の高効率化と最適種晶添加条件の検討 (2008)
  • Author(s): 三角隆太, ほか
  • Organizer: 日本海水学会第59年会
  • Place of Presentation: 長崎
  • Year and Date: 2008-06-06
• [Presentation] 半回分式撹拌型食塩蒸発晶析装置の高効率化と最適種晶添加条件の検討 (2008)
  • Author(s): 三角隆太
  • Organizer: 日本海水学会第59年会
  • Place of Presentation: ウェルシティ長崎(長崎)
  • Year and Date: 2008-06-06
• [Presentation] グランジュ粒子追跡法に基づく撹拌型晶析槽における結晶衝突現象の数値解析 (2008)
  • Author(s): 中西良輔、三角隆太, ほか
  • Organizer: 化学工学会73年会
  • Place of Presentation: 静岡大学
  • Year and Date: 2008-03-18
• [Presentation] ラグランジュ粒子追跡法に基づく撹拌型晶析槽における結晶衝突現象の数値解析 (2008)
  • Author(s): 中西 良輔
  • Organizer: 化学工学会 第73年会
  • Place of Presentation: 静岡大学(浜松)
  • Year and Date: 2008-03-18
• [Presentation] Complete Suspension of a High Concentration of Settling Solid Particles in a Draft-Tube Stirred Vessel (2007)
  • Author(s): R. Misumi, et al.
  • Organizer: 2007 AIChe Annual Meeting
  • Place of Presentation: Salt Lake City (USA)
  • Year and Date: 2007-11-08
• [Presentation] Complete Suspension of a High Concentration of Settling Solid Particles in a Draft-Tube Stirred Vessel (2007)
  • Author(s): Ryuta MISITMI
  • Organizer: 2007 AiChE Annual Meeting
  • Place of Presentation: Salt Lake City, USA
  • Year and Date: 2007-11-08
• [Presentation] ドラフトチューブ付撹拌型蒸発製塩槽における結晶成長過程に及ぼす操作条件の影響 (2007)
  • Author(s): 豊田智玄、三角隆太, ほか
  • Organizer: 化学工学会第39回秋季大会
  • Place of Presentation: 北海道大学
  • Year and Date: 2007-09-13
• [Presentation] レーザー散乱光計測を用いた回分式晶析槽における一次核発生挙動のその場計測法の検討 (2007)
  • Author(s): 山田大樹、三角隆太, ほか
  • Organizer: 化学工学会第39回秋季大会
  • Place of Presentation: 北海道大学
  • Year and Date: 2007-09-13
• [Presentation] レーザー散乱光計測を用いた回分式晶析槽における一次核発生挙動のその場計測法の検討 (2007)
  • Author(s): 山田 大樹
  • Organizer: 化学工学会 第39回秋季大会
  • Place of Presentation: 北海道大学(札幌)
  • Year and Date: 2007-09-13
• [Presentation] ドラフトチューブ付撹拌型蒸発製塩槽における結晶成長過程に及ぼす操作条件の影響 (2007)
  • Author(s): 豊田 智玄
  • Organizer: 化学工学会 第39回秋季大会
  • Place of Presentation: 北海道大学(札幌)
  • Year and Date: 2007-09-13
• [Remarks]
  • URL: http://www.msd.ynu.ac.jp/lab/kaminoyamalab/
• [Remarks]
  • URL: http://www.msd.ynu.ac.jp/lab/kaminoyamalab/