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Micro-simulation for inhaled particle tracking using image-based model human airways

Research Project

Project/Area Number 19760130
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Thermal engineering
Research InstitutionChiba University

Principal Investigator

TANAKA Gaku  Chiba University, 大学院・工学研究科, 准教授 (20292667)

Project Period (FY) 2007 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥3,800,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥600,000)
Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2008: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2007: ¥1,200,000 (Direct Cost: ¥1,200,000)
Keywords熱・物質輪送 / バイオメカニクス / 呼吸流れ / 振動流 / イメージベーストモデル / 数値シミュレーション / 流れの可視化 / PIV / 生物流体力学
Research Abstract

Computational fluid dynamics (CFD) simulations were carried out for particle tracking in oscillatory flow in a 3D realistic model of the human airways constructed based on X-ray CT images. Particle tracking revealed that the direction-dependent velocity profile with flow separation at the bifurcation promotes axial fluid dispersion in the airways. It was also found that the variance of the particles increases with the increase of volume change in an expanding and contracting model of small airways.

Report

(4 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • 2007 Annual Research Report
  • Research Products

    (18 results)

All 2010 2009 2008

All Journal Article (8 results) (of which Peer Reviewed: 1 results) Presentation (10 results)

  • [Journal Article] 気道モデル内振動流に発生する乱れのPIV計測2010

    • Author(s)
      高野了輔, 羽鳥彰浩, 田中学
    • Journal Title

      日本機械学会第22回バイオエンジニアリング講演論文集

      Pages: 68-68

    • Related Report
      2009 Annual Research Report
  • [Journal Article] Numerical simulation of oscillatory flow in realistic model human airways2009

    • Author(s)
      G. Inagaki, G. Tanaka, M. Hishida, H. Haneishi, X. Hu
    • Journal Title

      Journal of Fluid Science and Technology 4(3)

      Pages: 602-613

    • NAID

      130000129114

    • Related Report
      2009 Final Research Report
  • [Journal Article] Numerical simulation of oscillatory flow in realistic model human airways2009

    • Author(s)
      G.Inagaki, G.Tanaka, M.Hishida, H.Haneishi, X.Hu
    • Journal Title

      Journal of Fluid Science and Technology 4(3)

      Pages: 602-613

    • NAID

      130000129114

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 実形状肺気道モデル内振動流のPIV計測2009

    • Author(s)
      羽鳥彰浩, 高野了輔, 田中学
    • Journal Title

      日本機械学会第21回バイオエンジニアリング講演論文集

      Pages: 485-486

    • Related Report
      2008 Annual Research Report
  • [Journal Article] 気道内流れにおける混合の数値シミュレーション2008

    • Author(s)
      李成智, 稲垣原理, 田中学, 菱田誠, 世良俊博
    • Journal Title

      日本機械学会2008年度年次大会講演論文集 Vol.6

      Pages: 119-120

    • Related Report
      2008 Annual Research Report
  • [Journal Article] 実形状呼吸器官モデル内の気流解析2008

    • Author(s)
      田中学, 菱田誠, 羽石秀昭, 胡霄
    • Journal Title

      第47回日本生体医工学会大会プログラム・抄録集

      Pages: 275-275

    • Related Report
      2008 Annual Research Report
  • [Journal Article] 実形状鼻腔内流れの数値シミュレーション2008

    • Author(s)
      坂田拓也, 田中学, 菱田誠
    • Journal Title

      日本機械学会第20回バイオエンジニアリング講演会講演論文集

      Pages: 47-48

    • Related Report
      2007 Annual Research Report
  • [Journal Article] 実形状肺気道内流れの乱れ計測2008

    • Author(s)
      平野正泰, 羽鳥彰浩, 田中学, 菱田誠
    • Journal Title

      日本機械学会第20回バイオエンジニアリング講演会講演論文集

      Pages: 413-414

    • Related Report
      2007 Annual Research Report
  • [Presentation] 気道モデル内振動流に発生する乱れのPIV計測2010

    • Author(s)
      高野了輔, 羽鳥彰浩, 田中学
    • Organizer
      日本機械学会第22回バイオエンジニアリング講演論文集
    • Related Report
      2009 Final Research Report
  • [Presentation] Numerical simulation of oscillatory flow in an expanding and contracting model of small airways2009

    • Author(s)
      G.Tanaka
    • Organizer
      BMES Annual Meeting 2009
    • Place of Presentation
      Pittsburgh
    • Year and Date
      2009-10-08
    • Related Report
      2009 Annual Research Report
  • [Presentation] 気道内振動流に発生する乱れのPIV計測2009

    • Author(s)
      高野了輔, 羽鳥彰浩, 田中学
    • Organizer
      生体医工学シンポジウム2009講演予稿集
    • Related Report
      2009 Final Research Report
  • [Presentation] Numerical simulation of oscillatory flow in an expanding and contracting model of small airways2009

    • Author(s)
      M. Ohgawara, G. Inagaki, G. Tanaka, T. Sera
    • Organizer
      BMES 2009
    • Related Report
      2009 Final Research Report
  • [Presentation] Transition to turbulence during oscillatory flow in model human central airways2009

    • Author(s)
      R. Takano, A. Hatori, G. Tanaka
    • Organizer
      BMES 2009
    • Related Report
      2009 Final Research Report
  • [Presentation] 拡張収縮変型を伴う細気道内振動流の数値シミュレーション2009

    • Author(s)
      大河原正義, 稲垣原理, 田中学, 世良俊博
    • Organizer
      生体医工学シンポジウム2009講演予稿集
    • Related Report
      2009 Final Research Report
  • [Presentation] 実形状肺気道モデル内振動流のPIV計測2009

    • Author(s)
      羽鳥彰浩, 高野了輔, 田中学
    • Organizer
      日本機械学会第21回バイオエンジニアリング講演論文集
    • Related Report
      2009 Final Research Report
  • [Presentation] 気道内流れにおける混合の数値シミュレーション2008

    • Author(s)
      李成智, 稲垣原理, 田中学, 菱田誠, 世良俊博
    • Organizer
      日本機械学会2008年度年次大会講演論文集
    • Related Report
      2009 Final Research Report
  • [Presentation] 実形状呼吸器官モデル内の気流解析2008

    • Author(s)
      田中学, 菱田誠, 羽石秀昭, 胡霄
    • Organizer
      第47回日本生体医工学会大会プログラム・抄録集
    • Related Report
      2009 Final Research Report
  • [Presentation] 実形状肺気道内流れの乱れ計測2008

    • Author(s)
      平野正泰, 羽鳥彰浩, 田中学, 菱田誠
    • Organizer
      日本機械学会第20回バイオエンジニアリング講演論文集
    • Related Report
      2009 Final Research Report

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Published: 2007-04-01   Modified: 2016-04-21  

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