Study on Three-dimensional Trace-elemental Analysis in a Minute Area

• Project/Area Number: 19760619
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Nuclear engineering
• Research Institution: Japan Atomic Energy Agency
• Principal Investigator: SATOH Takahiro Japan Atomic Energy Agency, 放射線高度利用施設部, 研究職 (10370404)
• Project Period (FY): 2007 – 2008
• Project Status: Completed (Fiscal Year 2008)
• Budget Amount: ¥3,450,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥150,000); Fiscal Year 2008: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2007: ¥2,800,000 (Direct Cost: ¥2,800,000)
• Keywords: 加速器 / イオンビーム / 元素分析

Research Abstract

組織切片などの微小な試料を回転させ、イオンマイクロビームを用いた微量元素分析を行い、コンピュータ断層撮影法等で用いられている画像再構成の手法を適用し、微小試料内の微量元素の三次元分布を測定する手法を開発した。本手法では、X 線の発生量や吸収量を正確に補正する必要があるので、イオンマイクロビームを用いて試料の密度を三次元的に測定した。この測定結果から、微量元素分布の投影像を補正し画像再構成を行うことで、正確な微量元素の三次元分布を得ることに成功した。

Research Products

• [Journal Article] Three-dimensional measurement of elemental distribution in minute samples by combination of in-air micro-PIXE and STIM (2009)
  • Author(s): T. Satoh, M. Oikawa, T. Kamiya
  • Journal Title: Nuclear Instruments and Methods in Physics Research Section B Volume 267, Issues 12-13 Pages: 2125-2127
  • Peer Reviewed
• [Journal Article] Three-dimensional measurement of elemental distribution in minute samples by combination of in-air micro-PIXE and STIM (2009)
  • Author(s): T. Satoh, M. Oikawa, T. Kamiya
  • Journal Title: Nuclear Instruments and Methods in Physics Research Section B (in Press)
  • Peer Reviewed
• [Presentation] Three-Dimensional Measurement of Elemental Distribution in Minute Samples by Combination of In-air Micro-PIXE and STIM (2008)
  • Author(s): T. Satoh
  • Organizer: The 4th International Symposium on Biomedical Research Using Accelerator Technology
  • Place of Presentation: 群馬大学 (前橋)
  • Year and Date: 2008-11-16
• [Presentation] 大気マイクロPIXE を用いた微小試料の三次元元素分布測定 (2008)
  • Author(s): 佐藤隆博
  • Organizer: 第25回PIXEシンポジウム
  • Place of Presentation: 群馬大学 (前橋)
  • Year and Date: 2008-09-12
• [Presentation] Three-Dimensional Measurement of Elemental Distribution in Minute Biological Samples by In-air Micro-PIXE and STIM (2008)
  • Author(s): T. Satoh
  • Organizer: 11th International Conference on Nuclear Microprobe Technology and Applications
  • Place of Presentation: Debrecen (Hungary)
  • Year and Date: 2008-07-24
• [Presentation] Three-dimensional measurement of elemental distribution in minute samples by combination of in-air micro-PIXE and STIM (2008)
  • Author(s): T. Satoh, M. Oikawa, T. Kamiya
  • Organizer: 11th International Conference on Nuclear Microprobe Technology and Applications
  • Place of Presentation: Debrecen, Hungary
• [Presentation] 大気マイクロPIXEによる三次元元素分析 (2007)
  • Author(s): 佐藤隆博
  • Organizer: 第24回PIXEシンポジウム
  • Place of Presentation: 大妻女子大学 (多摩)
  • Year and Date: 2007-09-12
• [Presentation] 大気マイクロPIXEによる三次元元素分析 (2007)
  • Author(s): 佐藤隆博、他
  • Organizer: 第24回PIXEシンポジウム
  • Place of Presentation: 大妻女子大学社会情報学部
  • Year and Date: 2007-09-12