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Exploring the molecular mechanism of maternal inheritance

Research Project

Project/Area Number 19770050
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Morphology/Structure
Research InstitutionThe University of Tokyo

Principal Investigator

NISHIMURA Yoshiki  The University of Tokyo, 大学院・理学研究科, 助教 (70444099)

Project Period (FY) 2007 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥3,750,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥450,000)
Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2008: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2007: ¥1,800,000 (Direct Cost: ¥1,800,000)
Keywords母性遺伝 / cpDNA / mtDNA / 遺伝学 / 光ピンセット / 進化
Research Abstract

Uniparental inheritance of mitochondrial (mt) and chloroplast (cp) DNA is a phenomenon common to diverse taxa of plants and animals. Uniparental inheritance was long thought to be a passive outcome, based on the fact that eggs contain multiple numbers of organelles, while the contributions from male gametes are limited. However, it is likely to be more dynamic process, including the active digestion of male mt/cpDNA. In this project, Chlamydomonas mutants defective in uniparental inheritance of cpDNA were obtained and analyzed, which revealed that a homeotic gene that regulate the sexual development is also a key factor for uniparental inheritance.

Report

(4 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • 2007 Annual Research Report
  • Research Products

    (34 results)

All 2010 2009 2008 2007 Other

All Journal Article (7 results) (of which Peer Reviewed: 4 results) Presentation (24 results) Book (1 results) Remarks (2 results)

  • [Journal Article] Uniparental inheritance of cpDNA and the genetic control of sexual differentiation in Chlamydomonas reinhardtii.2010

    • Author(s)
      Nishimura, Y.
    • Journal Title

      J. Plant Res. 123巻

      Pages: 149-162

    • NAID

      10027217978

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Uniparental inheritance of cpDNA and the genetic control of sexual differentiation in Chlamydomonas reinhardtii.2010

    • Author(s)
      Yoshiki Nishimura
    • Journal Title

      Journal of Plant Research 123

      Pages: 149-162

    • NAID

      10027217978

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 葉緑体RNAの成熟と寿命2009

    • Author(s)
      西村芳樹, 鹿内利治
    • Journal Title

      蛋白質核酸酵素 54巻

      Pages: 2098-2101

    • Related Report
      2009 Final Research Report
  • [Journal Article] 葉緑体RNAの成熟と寿命2009

    • Author(s)
      西村芳樹、鹿内利治
    • Journal Title

      蛋白質核酸酵素 54

      Pages: 2098-2101

    • Related Report
      2009 Annual Research Report
  • [Journal Article] Genome analysis and its significance in four unicellular algae, Cyanidioshyzon merolae, Ostreococcus tauri, Chlamydomonas rei2008

    • Author(s)
      Misumi, O., Yoshida, Y., Nishida, K., Fujiwara, T., Sakajiri, T., Hirooka, S., Nishimua, Y., and Kuroiwa, T.
    • Journal Title

      Journal of Plant Research 121

      Pages: 3-17

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] クラミドモナスで母性遺伝のしくみを探る2008

    • Author(s)
      西村芳樹
    • Journal Title

      モデル生物 (化学同人) (印刷中)(掲載確定)

    • Related Report
      2007 Annual Research Report
  • [Journal Article] Differential replication of two chloroplast genome forms in heteroplasmic Chlamydomonas reinhardtii gametes contributes to alternative inheritance patterns

    • Author(s)
      Nishimura, Y、Stern, D.B.
    • Journal Title

      Genetics (in press)

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Presentation] 母性遺伝の分子機構を探る2010

    • Author(s)
      西村芳樹
    • Organizer
      第1回京大植物縦横無尽の会
    • Place of Presentation
      京都大学
    • Year and Date
      2010-03-17
    • Related Report
      2009 Annual Research Report
  • [Presentation] クラミドモナス葉緑体母性遺伝変異体BP31の解析からみえてきた接合子成熟プログラム2010

    • Author(s)
      西村芳樹
    • Organizer
      第51回日本植物生理学会年会
    • Place of Presentation
      熊本県、熊本大学
    • Related Report
      2009 Final Research Report
  • [Presentation] 新規ゼニゴケ核ゲノム形質転換選抜用マーカーの開発2010

    • Author(s)
      上田実, 石崎公庸, 大和勝幸, 河内孝之, 鹿内利治, 西村芳樹
    • Organizer
      第51回日本植物生理学会年会
    • Place of Presentation
      熊本県、熊本大学
    • Related Report
      2009 Final Research Report
  • [Presentation] クラミドモナス葉緑体母性遺伝変異体BP31の解析からみえてきた接合子成熟プログラム2010

    • Author(s)
      西村芳樹
    • Organizer
      第51回日本植物生理学会年会
    • Place of Presentation
      熊本大学
    • Related Report
      2009 Annual Research Report
  • [Presentation] 生殖プログラムと葉緑体母性遺伝~母性遺伝変異体BP31の解析~2009

    • Author(s)
      西村芳樹
    • Organizer
      植物細胞生物学若手の会
    • Place of Presentation
      奈良県、奈良先端科学技術大学院大学
    • Year and Date
      2009-12-21
    • Related Report
      2009 Final Research Report
  • [Presentation] 生殖プログラムと葉緑体母性遺伝 ~母性遺伝変異体BP31の解析~2009

    • Author(s)
      西村芳樹
    • Organizer
      植物細胞生物学若手の会
    • Place of Presentation
      奈良先端科学技術大学院大学
    • Year and Date
      2009-12-21
    • Related Report
      2009 Annual Research Report
  • [Presentation] 生殖プログラムと葉緑体母性遺伝~母性遺伝変異体BP31の解析~2009

    • Author(s)
      西村芳樹
    • Organizer
      第1回京大植物縦横無尽の会
    • Place of Presentation
      京都府、京都府立大学
    • Year and Date
      2009-03-17
    • Related Report
      2009 Final Research Report
  • [Presentation] 葉緑体とミトコンドリアの遺伝制御機構2009

    • Author(s)
      西村芳樹
    • Organizer
      第2回連携大学院セミナー京都
    • Place of Presentation
      京都府、京都大学
    • Year and Date
      2009-03-14
    • Related Report
      2009 Final Research Report
  • [Presentation] 葉緑体母性遺伝の分子機構の探求2009

    • Author(s)
      西村芳樹
    • Organizer
      日本植物学会第73回大会
    • Place of Presentation
      山形県、山形大学
    • Related Report
      2009 Final Research Report
  • [Presentation] 強害帰化雑草エゾノギシギシのメタボローム解析2009

    • Author(s)
      宮城敦子, 平林孝之, 高橋秀幸, 西村芳樹, 高原健太郎, 川合真紀, 内宮博文
    • Organizer
      第50回日本植物生理学会年会
    • Place of Presentation
      愛知県、名古屋大学
    • Related Report
      2009 Final Research Report
  • [Presentation] 葉緑体母性遺伝の分子機構の探求(招待講演)2009

    • Author(s)
      西村芳樹
    • Organizer
      日本植物学会第73回大会
    • Place of Presentation
      山形大学
    • Related Report
      2009 Annual Research Report
  • [Presentation] 母性遺伝の機構を探る~緑藻クラミドモナスをモデルとして~2008

    • Author(s)
      西村芳樹
    • Organizer
      光計測技術と生物発光リアルタイム測定システムの応用第2回研究会
    • Place of Presentation
      愛知県、名古屋大学
    • Year and Date
      2008-11-06
    • Related Report
      2009 Final Research Report
  • [Presentation] Repression of translation caused by antisense transcripts in chloroplasts2008

    • Author(s)
      Nishimura, Y., Matsuura, H., Kato, K., Kawai-Yamada, M., Uchimiya, H., Stern, D.B.
    • Organizer
      13th International Chlamydomonas Conference (EMBO workshop on the Cell and Molecular Biology of Chlamydomonas)
    • Place of Presentation
      イエール、フランス
    • Year and Date
      2008-05-27
    • Related Report
      2009 Final Research Report
  • [Presentation] クラミドモナス接合子特異的遺伝子EZY1の機能解析2008

    • Author(s)
      西村芳樹, 松島友美, 川合真紀, 内宮博文
    • Organizer
      第49回日本植物生理学会年会
    • Place of Presentation
      北海道、北海道大学
    • Year and Date
      2008-03-20
    • Related Report
      2009 Final Research Report
  • [Presentation] クラミドモナス接合子特異的遺伝子ezy1の機能解析2008

    • Author(s)
      西村芳樹、松島智美、川合真紀、内宮博文
    • Organizer
      第49回日本植物生理学会年会
    • Place of Presentation
      札幌
    • Year and Date
      2008-03-20
    • Related Report
      2007 Annual Research Report
  • [Presentation] Exploring the molecular mechanism of maternal inheritance2008

    • Author(s)
      Nishimura, Y.
    • Organizer
      International symposium "Bacteria made organelles made eukaryotic cells"
    • Place of Presentation
      東京都、東京大学
    • Related Report
      2009 Final Research Report
  • [Presentation] Molecular Mechanism of Maternal Inheritance -Reverse and Forward Genetic Approaches-2008

    • Author(s)
      Nishimura, Y.
    • Organizer
      Japan-Swiss Workshop on Photosynthetic Adaptation and Chloroplast Dynamics
    • Place of Presentation
      奈良県、ホテルフジタ奈良
    • Related Report
      2009 Final Research Report
  • [Presentation] 母性遺伝の分子機構~クラミドモナスEZY1遺伝子の逆遺伝学的解析~2008

    • Author(s)
      西村芳樹, 松島智美, 川合真紀, 内宮博文
    • Organizer
      日本植物学会第72回大会
    • Place of Presentation
      高知県、高知大学
    • Related Report
      2009 Final Research Report
  • [Presentation] タデ科ギシギシ属の代謝物解析2008

    • Author(s)
      宮城敦子, 高橋秀幸, 西村芳樹, 高原健太郎, 川合真紀, 内宮博文
    • Organizer
      日本植物学会第72回大会
    • Place of Presentation
      高知県、高知大学
    • Related Report
      2009 Final Research Report
  • [Presentation] Repression of translation caused by antisense transcripts in chloroplasts2008

    • Author(s)
      Yoshiki Nishimura, Hideyuki Matsuura, Ko Kato, Maki Kawai-Yamada, Hirofumi Uchimiya, and David B. Stern
    • Organizer
      13^<th>International Chlamydomonas Conference(EMBO workshop on the Cell and Molecular Biology of Chlamydomonas)
    • Place of Presentation
      イエール、フランス
    • Related Report
      2008 Annual Research Report
  • [Presentation] 母性遺伝の分子機構〜クラミドモナスezy1遺伝子の逆遺伝学的解析〜2008

    • Author(s)
      西村芳樹, 松島智美, 川合真紀, 内宮博文
    • Organizer
      日本植物学会第72回大会
    • Place of Presentation
      高知大学、高知
    • Related Report
      2008 Annual Research Report
  • [Presentation] 葉緑体におけるアンチセンスRNA2007

    • Author(s)
      西村芳樹
    • Organizer
      第71回植物学会大会シンポジウム「植物トランスクリプトーム解析の最前線」
    • Place of Presentation
      千葉県、東京理科大学
    • Year and Date
      2007-09-08
    • Related Report
      2009 Final Research Report
  • [Presentation] Biased maternal inheritance of heteroplasmic chloroplast genomes possibly caused by preferential replication2007

    • Author(s)
      ishimura, Y., Uchimiya, H., Stern, D.B.
    • Organizer
      第10回国際細胞共生学会
    • Place of Presentation
      グムンデン、オーストリア
    • Related Report
      2009 Final Research Report
  • [Presentation] Biased maternal inheritance of heteroplasmic chloroplast genomes possibly caused by preferential replication2007

    • Author(s)
      Yoshiki Nishimura, Hirofumi Uchimiya and David B. Stern
    • Organizer
      第10回 国際細胞共生学会
    • Place of Presentation
      グムンデン/オーストリア
    • Related Report
      2007 Annual Research Report
  • [Book] クラミドモナスで片親遺伝のしくみを探る、モデル生物ハンドブック、第9章2009

    • Author(s)
      西村芳樹
    • Publisher
      化学同人
    • Related Report
      2009 Final Research Report
  • [Remarks]

    • URL

      http://www.bot.kyoto-u.ac.jp/annual/5_iden.html

    • Related Report
      2009 Final Research Report
  • [Remarks]

    • URL

      http://www.bot.kyoto-u.ac.jp/annual/5_iden.html

    • Related Report
      2009 Annual Research Report

URL: 

Published: 2007-04-01   Modified: 2016-04-21  

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