Exploring the molecular mechanism of maternal inheritance
| Project/Area Number |
19770050
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Morphology/Structure
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| Research Institution | The University of Tokyo |
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Principal Investigator |
NISHIMURA Yoshiki The University of Tokyo, 大学院・理学研究科, 助教 (70444099)
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| Project Period (FY) |
2007 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥3,750,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥450,000)
Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2008: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2007: ¥1,800,000 (Direct Cost: ¥1,800,000)
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| Keywords | 母性遺伝 / cpDNA / mtDNA / 遺伝学 / 光ピンセット / 進化 |
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| Research Abstract |
Uniparental inheritance of mitochondrial (mt) and chloroplast (cp) DNA is a phenomenon common to diverse taxa of plants and animals. Uniparental inheritance was long thought to be a passive outcome, based on the fact that eggs contain multiple numbers of organelles, while the contributions from male gametes are limited. However, it is likely to be more dynamic process, including the active digestion of male mt/cpDNA. In this project, Chlamydomonas mutants defective in uniparental inheritance of cpDNA were obtained and analyzed, which revealed that a homeotic gene that regulate the sexual development is also a key factor for uniparental inheritance.
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Report
(4 results)
Research Products
(34 results)
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[Journal Article] Genome analysis and its significance in four unicellular algae, Cyanidioshyzon merolae, Ostreococcus tauri, Chlamydomonas rei2008
Author(s)
Misumi, O., Yoshida, Y., Nishida, K., Fujiwara, T., Sakajiri, T., Hirooka, S., Nishimua, Y., and Kuroiwa, T.
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Journal Title
Journal of Plant Research 121
Pages: 3-17
Related Report
Peer Reviewed
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[Presentation] Repression of translation caused by antisense transcripts in chloroplasts2008
Author(s)
Nishimura, Y., Matsuura, H., Kato, K., Kawai-Yamada, M., Uchimiya, H., Stern, D.B.
Organizer
13th International Chlamydomonas Conference (EMBO workshop on the Cell and Molecular Biology of Chlamydomonas)
Place of Presentation
イエール、フランス
Year and Date
2008-05-27
Related Report
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