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Environmental adaptation and body fluid homeostasis of fish by transporting epithelial cells

Research Project

Project/Area Number 19770057
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Animal physiology/Animal behavior
Research InstitutionTokyo Institute of Technology

Principal Investigator

KATO Akira  Tokyo Institute of Technology, 大学院・生命理工学研究科, 助教 (40311336)

Project Period (FY) 2007 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥240,000)
Fiscal Year 2008: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2007: ¥2,600,000 (Direct Cost: ¥2,600,000)
Keywords魚類生理 / 電気生理 / 体液ホメオスタシス / イオン輸送体 / フグゲノム / 重炭酸輸送体 / 硫酸輸送体 / 輸送上皮細胞 / 魚類生理学 / 電気生理学
Research Abstract

魚類が淡水や海水の中で体液を人とほぼ同じ組成に保つ仕組みを, エラ, 腎臓, 腸によるイオン輸送の結果として理解することを目標に, トラフグ(ゲノム配列が公開)の近縁種で淡水・海水の両環境で生息できるメフグのイオン輸送体遺伝子を解析した。淡水魚が尿から水を排泄する仕組み, 海水魚が糞からカルシウムを排泄する仕組み, 及び海水魚が尿から硫酸イオンを排泄する仕組みに関わる遺伝子を明らかにした。

Report

(3 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • Research Products

    (17 results)

All 2008 2007 Other

All Journal Article (12 results) (of which Peer Reviewed: 6 results) Presentation (4 results) Remarks (1 results)

  • [Journal Article] Identification of intestinal bicarbonate transporters involved in formation of carbonate precipitates to stimulate water absorption in marine teleost fish2008

    • Author(s)
      Kurita Y, Nakada T, Kato A, Doi H, Mistry AC, Chang MH, Romero MF, Hirose S
    • Journal Title

      Am J Physiol Regul Integr Comp Physiol 294

    • Related Report
      2008 Final Research Report
  • [Journal Article] Identification of intestinal bicarbonate transporters involved in formation of carbonate precipitates to stimulate water absorption in marine teleost fish2008

    • Author(s)
      Kurita Y, Nakada T, Kato A, Doi H, Mistry AC, Chang MH. Romero MF, Hirose S.
    • Journal Title

      Am J Physiol Regul Integr Comp Physiol 294(4)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Characterization of the column and autocellular junctions that define the vasculature of gill lamellae2007

    • Author(s)
      Kato A, Nakamura K, Kudo H, Tran YH, Yamamoto Y, Doi H, Hirose S
    • Journal Title

      J Histochem Cytochem 55

      Pages: 941-53

    • Related Report
      2008 Final Research Report
  • [Journal Article] Fish calcitonin receptor has novel features2007

    • Author(s)
      Nag K, Kato A, Sultana N, Ogoshi M, Takei Y, Hirose S
    • Journal Title

      Gen Comp Endocrinol 154

      Pages: 48-58

    • Related Report
      2008 Final Research Report
  • [Journal Article] Headless splice variant acting as dominant negative calcitonin receptor2007

    • Author(s)
      Nag K, Sultana N, Kato A, Hirose S
    • Journal Title

      Biochem Biophys Res Commun 362

      Pages: 1037-43

    • Related Report
      2008 Final Research Report
  • [Journal Article] Ammonia secretion from fish gill depends on a set of Rh glycoproteins2007

    • Author(s)
      Nakada T, Westhoff CM, Kato A, Hirose S
    • Journal Title

      FASEB J

    • Related Report
      2008 Final Research Report
  • [Journal Article] Pillar cell and erythrocyte localization of fugu ET(A) receptor and its implication2007

    • Author(s)
      Sultana N, Nag K, Kato A, Hirose S
    • Journal Title

      Biochem Biophys Res Commun

    • Related Report
      2008 Final Research Report
  • [Journal Article] Headless splice variant acting as dominant negative calcitonin receptor2007

    • Author(s)
      Nag K, Sultana N, Kato A, Hirose S.
    • Journal Title

      Biochem. Biophys. Res. Commun. 362

      Pages: 1037-43

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Fish calcitonin receptor has novel features2007

    • Author(s)
      Nag K. Kato A, Sultana N, Ogoshi M, Takei Y, Hirose S.
    • Journal Title

      Gen. Comp. Endocrinol. 154

      Pages: 48-58

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Characterization of the column and autocellular junctions that define the vasculature of gill lamellac2007

    • Author(s)
      Kato A, Nakamura K, Kudo H, Tran YH, Yamamoto Y, Doi H, Hirose S.
    • Journal Title

      J. Histochem. Cytochem. 55

      Pages: 941-53

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Pillar cell and erythrocyte localization of fugu ET(A) receptor and its implication2007

    • Author(s)
      Sultana N, Nag K, Kato A, Hirose S.
    • Journal Title

      Biochem. Biophys. Res. Commun. 355

      Pages: 149-55

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Ammonia secretion from fish gill depends on a set of Rh glycoproteins2007

    • Author(s)
      Nakada T, Westhoff CM, Kato A, Hirose S.
    • Journal Title

      FASEB J. 21

      Pages: 1067-74

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Presentation] 海水魚の硫酸排泄機構の解析2008

    • Author(s)
      加藤 明, 中田 勉, 栗田 志広, 土井 啓行, Min-Hwang Chang, Michael F. Romero, 広瀬茂久
    • Organizer
      第3回トランスポーター研究会
    • Place of Presentation
      京都
    • Year and Date
      2008-06-08
    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Presentation] Functional Characterization of Pufferfish Slc26a6A and Slc26a6B2008

    • Author(s)
      Kato A, Chang MH, Kurita Y, Nakada T, Hirose S, Romero MF
    • Organizer
      Experimental Biology 2008
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2008-04-08
    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Presentation] フグSlc26陰イオン交換輸送体の活性と海水適応における役割2007

    • Author(s)
      加藤 明, Min-Hwang Chang, 栗田 志広, 中田 勉, 広瀬 茂久, Michael F. Romero
    • Organizer
      トランスポーター研究会第1回関東部会
    • Place of Presentation
      横浜
    • Year and Date
      2007-12-10
    • Related Report
      2008 Final Research Report
  • [Presentation] フグSlc26陰イオン交換輸送体の活性と海水適応における役割2007

    • Author(s)
      加藤 明
    • Organizer
      トランスポーター研究会 第1回関東部会
    • Place of Presentation
      横浜(東京工業大学)
    • Year and Date
      2007-12-10
    • Related Report
      2007 Annual Research Report
  • [Remarks]

    • URL

      http://www.hirose.bio.titech.ac.jp/

    • Related Report
      2008 Annual Research Report

URL: 

Published: 2007-04-01   Modified: 2016-04-21  

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