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Molecular analysis of CaM kinase cascade in vertebrate embryogenesis

Research Project

Project/Area Number 19770110
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Functional biochemistry
Research InstitutionKagawa University

Principal Investigator

SUEYOSHI Noriyuki  Kagawa University, 農学部, 准教授 (90346635)

Project Period (FY) 2007 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥3,600,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥300,000)
Fiscal Year 2008: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2007: ¥2,300,000 (Direct Cost: ¥2,300,000)
KeywordsCaMKP / CaMKP-N / apoptosis / zebrafish / CaM kinase
Research Abstract

多機能性CaMキナーゼを脱リン酸化して負に制御するCaMKPとCaMKP-Nをなくしたゼブラフィッシュ胚では、両酵素の発現部位と一致してアポトーシス(細胞の自殺)が観察された。このことは、脊椎動物の胚発生において、CaMキナーゼによるシグナル伝達経路が重要な役割を持つことを示す。CaMKPは基質であるCaMキナーゼによってリン酸化され、活性化された。一方でCaMKP-NはプロテアーゼによってC末を分解されることによって活性化された。

Report

(3 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • Research Products

    (79 results)

All 2009 2008 2007

All Journal Article (32 results) (of which Peer Reviewed: 30 results) Presentation (47 results)

  • [Journal Article] Novel Ca2+/calmodulin-dependent protein kinase expressed in actively growing mycelia of the basidiomycetous mushroom Coprinus cinereus.2009

    • Author(s)
      Kaneko, K., Yamada, Y., Sueyoshi, N., Watanabe, A., Asada, Y., Kameshita, I.
    • Journal Title

      Biochim. Biophys. Acta. 1790

      Pages: 71-79

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Mechanistic insights into the hydrolysis and synthesis of ceramide by neutral ceramidase.2009

    • Author(s)
      Inoue, T., Okino, N., Kakuta, Y., Hijikata, A., Okano, H., Goda, H.M., Tani, M., Sueyoshi, N., Kambayashi, K., Matsumura, H., Kai, Y., Ito, M.
    • Journal Title

      J. Biol. Chem. 284

      Pages: 9566-9577

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Novel Ca2+/calmodulin-dependent protein kinase expressed in actively growing mycelia of the basidiomycetous mushroom Conrinus cinereus2009

    • Author(s)
      Kaneko, K., Yamada, Y., Sueyoshi ; N., Watanabe, A., Asada. Y., Kameshita. I.
    • Journal Title

      Biochim. Biophys. Acta 1790

      Pages: 71-79

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Mechanistic insights into the hydrolysis and synthesis of ceramide by neutral ceramidase2009

    • Author(s)
      Inoue, T., Okino ; N., Kakuta, Y., Hijikata, A., Okano, H., Goda, H.M. ; Tani, M., Sueyoshi, N., Kambayashi, K., Matsumura, H., Kai, Y, Ito, M.
    • Journal Title

      J. Biol. Chem 284

      Pages: 9566-9577

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Negative regulation of multifunctional Ca2+/calmodulin-dependent protein kinases : physiological and pharmacological significance of protein phosphatases.2008

    • Author(s)
      Ishida, A., Sueyoshi, N., Shigeri, Y., Kameshita, I.
    • Journal Title

      Br. J. Pharmacol. 154

      Pages: 729-740

    • NAID

      120001041388

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Tyrosine kinase activity of a Ca2+/calmodulin-dependent protein kinase II catalytic fragment.2008

    • Author(s)
      Sugiyama, Y., Ishida, A., Sueyoshi, N., Kameshita, I.
    • Journal Title

      Biochem. Biophys. Res. Commun. 377

      Pages: 648-652

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Cyclin-dependent kinase-like 5 binds and phosphorylates DNA methyltransferase 1.2008

    • Author(s)
      Kameshita, I., Sekiguchi, M., Hamasaki, D., Sugiyama, Y., Hatano, N., Suetake, I., Tajima, S., Sueyoshi, N.
    • Journal Title

      Biochem. Biophys. Res. Commun. 377

      Pages: 1162-1167

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Activation of SAD kinase by Ca2+/calmodulin-dependent protein kinase kinase.2008

    • Author(s)
      Fujimoto, T., Yurimoto, S., Hatano, N., Nozaki, N., Sueyoshi, N., Kameshita, I., Mizutani, A., Mikoshiba, K., Kobayashi, R., Tokumitsu, H.
    • Journal Title

      Biochemistry 47

      Pages: 4151-4159

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Two-dimensional gel electrophoretic analysis of cyanogen bromide fragments containing subdomain VIB of protein kinases using a Multi-PK antibody.2008

    • Author(s)
      Sugiyama, Y., Shimomura, S., Sueyoshi, N., Kameshita, I.
    • Journal Title

      Anal. Biochem 373

      Pages: 173-175

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Ca2+/カルモジュリン依存性プロテインキナーゼによるシグナル伝達-スイッチオン/オフの制御機構と疾患とのかかわり-2008

    • Author(s)
      茂里康、石田敦彦、末吉紀行、亀下勇
    • Journal Title

      蛋白質核酸酵素 53

      Pages: 1360-1367

    • NAID

      40016204748

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Tyrosine kinase activity of a Ca2+/calmodulindependent protein kinase II catalytic fragment2008

    • Author(s)
      Sugiyama, Y, Ishida, A., Sueyoshi, N., Kameshita, I.
    • Journal Title

      Biochem. Biophys. Res. Commun 377

      Pages: 648-652

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cyclindependent kinase-like 5 binds and phosphorylates DNA methyltransferase 12008

    • Author(s)
      Kameshita, I., Sekiguchi, M., Hamasaki, D., Sugiyama, Y, Hatano, N., Suetake, I., Tajima, S., Sueyoshi, N.
    • Journal Title

      Biochem. Biophys. Res. Commun 377

      Pages: 1162-1167

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Activation of SAD kinase by Ca2+/calmodulindependent protein kinase kinase2008

    • Author(s)
      Fujimoto, T., Yurimoto, S., Hatano, N., Nozaki, N., Sueyoshi, N., Kameshita, I., Mizutani, A., Mikoshiba, K., Kobayashi. R.. Tokumitsu, H.
    • Journal Title

      Biochemistry 47

      Pages: 4151-4159

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Twodimensional gel electrophoretic analysis of cyanogen.bromide fragments containing subdornain VIB of nrotein lcinases using a Multi-PK antibody2008

    • Author(s)
      Sugiyaina, Y., Shimomura,S., Suevoshi, N.. Kameshita, I.
    • Journal Title

      Anal. Biochem 373

      Pages: 173-175

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Ca2+/カルモジュリン依存性ロテインキナーゼによるシグナル伝達-スイッチオン/オフの制御機構と疾患とのかかわり-2008

    • Author(s)
      茂里康、石田敦彦、末吉紀行、亀下勇
    • Journal Title

      蛋白質核酸酵素 53

      Pages: 1360-1367

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Negative regulation of multifunctional Ca2+/calmodulin-dependent protein kinases physiological and pharmacological significance of protein phosphatases2008

    • Author(s)
      Ishida, A., Sueyoshi, N., Shigeri, Y., Kameshita, I.
    • Journal Title

      Br. J. Pharmacol 154

      Pages: 729-740

    • NAID

      120001041388

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Two-dimensional gel electrophoretic analysis of cyanogens bromide fragments containing subdomain VIB of protein kinases using Multi-PK antibody.2008

    • Author(s)
      Sueiyama, Y., Shimomura, S., Sueyoshi, N.他
    • Journal Title

      Anal. Biochem. 373

      Pages: 173-175

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Knockdown of nuclear Ca2+/calmodulin-dependent protein kinase phosphatase causes developmental abnormalities in zebrafish2007

    • Author(s)
      Nimura, T., Sueyoshi, N., Ishida, A., Yoshimura, Y., Ito, M., Tokumitsu, H., Shigeri, Y., Nozaki, N., and Kameshita, I.
    • Journal Title

      Arch. Biochem. Biophys 457

      Pages: 205-216

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Expression of a functional sphingomyelinase of Pseudomonas sp. TK4 in mammalian cells2007

    • Author(s)
      Horibata, Y., Sueyoshi, N., Ito, M.
    • Journal Title

      Biosci. Biotechnol. Biochem 71

      Pages: 603-606

    • NAID

      10027512136

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Recent advances in technologies for analyzing protein kinases2007

    • Author(s)
      Ishida, A., Kameshita, I., Sueyoshi, N., Taniguchi, T., and Shigeri, Y.
    • Journal Title

      J. Pharmacol. Sci. 103

      Pages: 5-11

    • NAID

      10024311808

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Inhibitors of the Ca2+/calmodulin-dependent protein kinase phosphatase family (CaMKP and CaMKP-N)2007

    • Author(s)
      Sueyoshi, N., Takao, T., Nimura, T., Sugiyama, Y., Numano, T., Shigeri, Y., Taniguchi, T., Kameshita, I., Ishida, A.
    • Journal Title

      Biochem. Biophys. Res. Commun 363

      Pages: 715-721

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Involvement of Ca2+/calmodulin-dependent protein kinases in mycelial growth of the basidiomycetous mushroom, Coprinus cinereus2007

    • Author(s)
      Kameshita, I., Yamada, Y., Nishida, T., Sugiyama, Y., Sueyoshi, N., Watanabe, A., Asada, Y.
    • Journal Title

      Biochim. Biophys. Acta 1770

      Pages: 1395-1403

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Expression, characterization, and gene knockdown of zebrafish doublecortin-like protein kinase2007

    • Author(s)
      Shimomura, S., Nagamine, T., Nimura, T., Sueyoshi, N., Shigeri, Y., Kameshita, I.
    • Journal Title

      Arch. Biochem. Biophys 463

      Pages: 218-230

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Two-dimensional gel electrophoretic analysis of cyanogens bromide fragments containing subdomain VIB of protein kinases using Multi-PK antibody2007

    • Author(s)
      Sugiyama, Y., Shimomura, S., Sueyoshi, N., Kameshita, I
    • Journal Title

      Anal. Biochem 373

      Pages: 173-175

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] カルモジュリンキナーゼに特異的に作用するホスファターゼ2007

    • Author(s)
      末吉紀行、二村貴樹、亀下勇
    • Journal Title

      バイオサイエンスとインダストリー 65

      Pages: 244-245

    • Related Report
      2008 Final Research Report
  • [Journal Article] Knockdown of nuclear Ca^<2+>calmodulin-dependent protein kinase phosphatase causes developmental abnormalities in zebrafish2007

    • Author(s)
      Nimura, T・, Sueyoshi, N.他,
    • Journal Title

      Arch. Biochem. Biophys. 457

      Pages: 205-216

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Expression of a functional sphingomyelinase of Pseudomonas sp. TK4 in mammalian cells2007

    • Author(s)
      Horibata, Y.Sueyoshi, N, 他
    • Journal Title

      Biosci. Biotechnol. Biochem. 71

      Pages: 603-606

    • NAID

      10027512136

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Recent advances in technologies for analyzing protein kinases2007

    • Author(s)
      Ishida, A., Kameshita, I., Sueyoshi, N.他
    • Journal Title

      J. Pharmacol. Sci. 103

      Pages: 5-11

    • NAID

      10024311808

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Inhibitors of the Ca^<2+>/ Vcalmodulin-dependent protein kinase phosphatas family (CaMKP and CaMKP-N).2007

    • Author(s)
      Sueyoshi, N.他
    • Journal Title

      Biochem. Biophys. Res. Commun. 363

      Pages: 715-721

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Involvement of Ca^<2+>/calmodulin-dependent protein kinases in mycelialgrowth of the basidiomycetous mushroom, Coprinus cinereus.2007

    • Author(s)
      Kameshita, I., Yamada, Y., Nishida, T., Sugiyama, Y., Sueyoshi, N.他
    • Journal Title

      Biochim. Biophys. Acta. 1770

      Pages: 1395-1403

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Expression, characterization, and gene knockdown of zebrafish doublecortin-like protein kinase.2007

    • Author(s)
      Shimomura, S., Nagamine, T・, Nimura, T., Sueyoshi, N.他
    • Journal Title

      Arch. Biochem. Biophys. 463

      Pages: 218-230

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] カルモジュリンキナーゼに特異的に作用するホスファターゼ2007

    • Author(s)
      末吉紀行, 二村貴樹, 亀下男
    • Journal Title

      バイオサイエンスとインダストリー 65

      Pages: 244-245

    • Related Report
      2007 Annual Research Report
  • [Presentation] Ca2+/calmodulin-dependent protein kinase phosphatase (CaMKP) is indispensable for normal embryogenesis in zebrafish, Danio rerio.2008

    • Author(s)
      Sueyoshi, N., Ishida, A., Kameshita, I.
    • Organizer
      8th International Conference on Protein Phosphatases
    • Place of Presentation
      Gunma
    • Year and Date
      2008-11-12
    • Related Report
      2008 Final Research Report
  • [Presentation] Ca2+/calmodulin-dependent protein kinase phosphatase (CaMKP) is indispensable for normal embryogenesis in zebrafish, Danio rerio2008

    • Author(s)
      Sueyoshi, N., Ishida, A., Kameshita, I.
    • Organizer
      8th International Conference on Protein Phosphatases
    • Place of Presentation
      群馬
    • Year and Date
      2008-11-12
    • Related Report
      2008 Annual Research Report
  • [Presentation] Catalytic properties of zebrafish boublecortin-like protein kinase (zDCLK).2008

    • Author(s)
      Shimomura, S., Nagamine, T., Nimura, T., Sueyoshi, N., Kameshita, I.
    • Organizer
      11th IUBMB Conference
    • Place of Presentation
      Athens,Greece
    • Year and Date
      2008-07-01
    • Related Report
      2008 Final Research Report
  • [Presentation] Calmodulin-dependent protein kinase IV regulates insulin secretion under the glucotoxic condition in INS-1 rat insulinoma cell line.2008

    • Author(s)
      Sugiyama, Y., Murao, K., Imachi, H., Sueyoshi, N., Ishida, I., Kameshita, I.
    • Organizer
      11th IUBMB Conference
    • Place of Presentation
      Athens,Greece
    • Year and Date
      2008-07-01
    • Related Report
      2008 Final Research Report
  • [Presentation] Catalytic properties of zebrafish boublecortin-like protein kinase (zDCLK)2008

    • Author(s)
      Shimomura, S., Nagamine, T., Nimura, T., Sueyoshi, N., Kameshita. I.
    • Organizer
      11th IUBMB Conference
    • Place of Presentation
      ギリシャ アテネ
    • Year and Date
      2008-07-01
    • Related Report
      2008 Annual Research Report
  • [Presentation] Calmoduliri-dependent protein kinase IV regulates insulin secretion under the glucotoxic condition in INS-1 rat insulinoma cell line2008

    • Author(s)
      Sugiyama, Y, Murao, K., Imachi, H., Sueyoshi, N., Ishida, I., Kameshita, I.
    • Organizer
      11th IUBMB Conference
    • Place of Presentation
      ギリシャ アテネ
    • Year and Date
      2008-07-01
    • Related Report
      2008 Annual Research Report
  • [Presentation] 担子菌C.cinereusの生長菌糸に発現するCa2+/calmodulin依存性プロテインキナーゼ2008

    • Author(s)
      金子啓祐,山田裕介,末吉紀行,渡邉彰,麻田恭彦,亀下勇
    • Organizer
      第49回日本生化学会中国・四国支部例会
    • Place of Presentation
      高松
    • Year and Date
      2008-05-16
    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Presentation] 緑膿菌由来の中性セラミダーゼのX線結晶構造解析と反応機構の解明2008

    • Author(s)
      沖野望,井上豪,角田佳充,土方敦司,岡野浩幸,上林浩二,合田(問註所)初美,谷元洋,末吉紀行,松村浩由,甲斐泰,伊東信
    • Organizer
      第31回日本分子生物学会年会第81回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Presentation] ゼブラフィッシュDoublecortin-like protein kinase (zDCLK)の活性化機構と活性型zDCLKを用いた内在性基質の探索2008

    • Author(s)
      下村幸子,永峰賢,波多野直哉,末吉紀行,亀下勇
    • Organizer
      第31回日本分子生物学会年会第81回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Related Report
      2008 Final Research Report
  • [Presentation] 各種変異体を用いたゼブラフィッシュDoublecortin-like protein kinaseの微小管結合状態の解析2008

    • Author(s)
      永峰賢,下村幸子,末吉紀行,亀下勇
    • Organizer
      第31回日本分子生物学会年会第81回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Presentation] 担子菌Coprinus cinereusに発現するCoPK032の発現クローニングと機能解析2008

    • Author(s)
      金子啓祐,末吉紀行,渡邉彰,麻田泰彦,亀下勇
    • Organizer
      第31回日本分子生物学会年会第81回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Presentation] ミヤコグサに発現するプロテインキナーゼPKL012008

    • Author(s)
      西尾和士,下村幸子,西田哲之,末吉紀行,野村美加,田島茂行,亀下勇
    • Organizer
      第31回日本分子生物学会年会第81回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Related Report
      2008 Final Research Report
  • [Presentation] Ca2+/calmodulin-dependent protein kinase II触媒断片のチロシンキナーゼ活性2008

    • Author(s)
      杉山康憲,石田敦彦,末吉紀行,亀下勇
    • Organizer
      第31回日本分子生物学会年会第81回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Related Report
      2008 Final Research Report
  • [Presentation] ゼブラフィッシュ脳における核局在型CaMキナーゼホスファターゼ(CaMKP-N)の分解断片の解析2008

    • Author(s)
      二村貴樹、末吉紀行、亀下勇
    • Organizer
      第31回日本分子生物学会年会第81回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Presentation] ゼブラフィッシュDoublecortin-like protein kinase(zDCLK)の活性化機構と活性型zDCLKを用いた内在性基質の探索2008

    • Author(s)
      下村幸子, 永峰賢, 波多野直哉, 末吉紀行, 亀下勇
    • Organizer
      第31回日本分子生物掌会年会第81回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Related Report
      2008 Annual Research Report
  • [Presentation] Ca+/calmodulin-dependent protein kinaseII触媒断片のテロシンキナーゼ活性2008

    • Author(s)
      杉山康憲, 石田敦彦, 末吉紀行, 亀下勇
    • Organizer
      第31回日本分子生物学会年会第81回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Related Report
      2008 Annual Research Report
  • [Presentation] ミヤコグサに発現するプロテインキナーゼPKLO12008

    • Author(s)
      西尾和士, 下村幸子, 西田哲之, 末吉紀行, 野村美加, 田島茂行, 亀下勇
    • Organizer
      第31回日本分子生物学会年会第81回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Related Report
      2008 Annual Research Report
  • [Presentation] CaMキナーゼホスファターゼの特異的阻害剤2007

    • Author(s)
      末吉紀行,亀下勇
    • Organizer
      国際バイオEXPO&国際バイオフォーラム2007
    • Place of Presentation
      東京
    • Year and Date
      2007-06-21
    • Related Report
      2008 Final Research Report
  • [Presentation] CaMキナーゼホスフアターゼの特異的阻害剤2007

    • Author(s)
      末吉紀行他
    • Organizer
      国際バイオEXPO&国際バイオフォーラム2007
    • Place of Presentation
      東京
    • Year and Date
      2007-06-21
    • Related Report
      2007 Annual Research Report
  • [Presentation] Coprinus cinereusのカルモデュリン依存性プロテインキナーゼの検出と遺伝子クローニング2007

    • Author(s)
      山田裕介,西田哲之,杉山康憲,末吉紀行,渡邉彰,麻田恭彦,亀下勇
    • Organizer
      日本農芸化学会2007年度大会
    • Place of Presentation
      東京
    • Year and Date
      2007-04-01
    • Related Report
      2008 Final Research Report
  • [Presentation] 緑膿菌セラミダーゼの構造と機能の解析2007

    • Author(s)
      沖野望,井上豪,岡野浩幸,上林浩二,合田(問註所)初美,谷元洋,末吉紀行,角田佳充,伊東信
    • Organizer
      第30回日本分子生物学会年会第80回日本生化学会大会合同大会
    • Place of Presentation
      横浜
    • Related Report
      2008 Final Research Report
  • [Presentation] 糖毒性状態のINS-1細胞においてCaMKIVがインスリン分泌を制御する2007

    • Author(s)
      杉山康憲,村尾孝児,井町仁美,末吉紀行,石田俊彦,亀下勇
    • Organizer
      第30回日本分子生物学会年会第80回日本生化学会大会合同大会
    • Place of Presentation
      横浜
    • Related Report
      2008 Final Research Report
  • [Presentation] Catalytic properties of zebrafish Doublecortin-like protein kinase (zDCLK)2007

    • Author(s)
      下村幸子,二村貴樹,末吉紀行,亀下勇
    • Organizer
      第30回日本分子生物学会年会第80回日本生化学会大会合同大会
    • Place of Presentation
      横浜
    • Related Report
      2008 Final Research Report
  • [Presentation] S100タンパク質によるHsp70/Hsp90分子シャペロン複合体の形成調節2007

    • Author(s)
      小池克英,嶋本聖子,末吉紀行,亀下勇,徳光浩,小林良二
    • Organizer
      第30回日本分子生物学会年会第80回日本生化学会大会合同大会
    • Place of Presentation
      横浜
    • Related Report
      2008 Final Research Report
  • [Presentation] DNA methyltransferase 1 (Dnmt1)のN末端領域にはCyclin-dependent protein kinase like 5 (CDKL5)が結合する2007

    • Author(s)
      濱崎大介,関口茉里,大下幸助,波多野直哉,徳田雅明,末吉紀行,末武勲,田嶋正二,亀下勇
    • Organizer
      第30回日本分子生物学会年会第80回日本生化学会大会合同大会
    • Place of Presentation
      横浜
    • Related Report
      2008 Final Research Report
  • [Presentation] Ca2+/CaM依存性プロテインキナーゼホスファターゼ(CaMKP)阻害剤のスクリーニング2007

    • Author(s)
      沼野琢旬,末吉紀行,高尾俊彦,石田敦彦,谷口隆信,二村貴樹,杉山康憲,茂里康,亀下勇
    • Organizer
      第30回日本分子生物学会年会第80回日本生化学会大会合同大会
    • Place of Presentation
      横浜
    • Related Report
      2008 Final Research Report
  • [Presentation] ゼブラフィッシュ初期発生系を用いた酸性スフィンゴミエリナーゼの解析2007

    • Author(s)
      堀佑希,吉村征浩,末吉紀行,沖野望,伊東信
    • Organizer
      第30回日本分子生物学会年会第80回日本生化学会大会合同大会
    • Place of Presentation
      横浜
    • Related Report
      2008 Final Research Report
  • [Presentation] SAD-BのCaM-KKによるリン酸化と活性化2007

    • Author(s)
      藤本智仁,揺本沙紀,波多野直哉,野崎直仁,末吉紀行,亀下勇,小林良二,徳光浩
    • Organizer
      第30回日本分子生物学会年会第80回日本生化学会大会合同大会
    • Place of Presentation
      横浜
    • Related Report
      2008 Final Research Report
  • [Presentation] ゼブラフィッシュCyclin-dependent protein kinase like 5 (zCDKL5)のcDNAクローニングとノックダウン2007

    • Author(s)
      関口茉里,末吉紀行,亀下勇
    • Organizer
      第30回日本分子生物学会年会第80回日本生化学会大会合同大会
    • Place of Presentation
      横浜
    • Related Report
      2008 Final Research Report
  • [Presentation] マルチPK抗体を用いたプロテインキナーゼ同定法の確立とその応用2007

    • Author(s)
      杉山康憲,下村幸子,末吉紀行,亀下勇,村尾孝児
    • Organizer
      第58回日本電気泳動学会総会
    • Place of Presentation
      山口
    • Related Report
      2008 Final Research Report 2007 Annual Research Report
  • [Presentation] 担子菌Coprinus cinereusの菌糸に発現する新規プロテインキナーゼの発現クローニングとその解析2007

    • Author(s)
      金子啓祐,山田裕介,杉山康憲,末吉紀行,渡邉彰,麻田恭彦,亀下勇
    • Organizer
      2007年度日本農芸化学会中四国・西日本支部合同大会
    • Place of Presentation
      山口
    • Related Report
      2008 Final Research Report
  • [Presentation] Knockdown of nuclear calcium/calmodulin-dependent protein kinase phosphatase causes developmental abnormalities in zebrafish2007

    • Author(s)
      Nimura, T., Sueyoshi, N., Ishida, A., Kameshita, I.
    • Organizer
      EuroPhosphatases 2007 "Protein Phosphatases in Health and Disease"
    • Place of Presentation
      Aveiro, Portugal
    • Related Report
      2008 Final Research Report
  • [Presentation] DNAメチルトランスフェラーゼ1(Dnmt1)のN末端領域に結合するプロテインキナーゼの同定と解析2007

    • Author(s)
      関口茉里,濱崎大介,波多野直哉,末吉紀行,大下幸介,末武勲,田嶋正二,亀下勇
    • Organizer
      日本生化学会中四国支部会
    • Place of Presentation
      高知
    • Related Report
      2008 Final Research Report
  • [Presentation] Ca2+/CaM依存性プロテインキナーゼホスファターゼ(CaMKP)の各種変異体を用いた機能解析2007

    • Author(s)
      沼野琢旬,多田幸代,末吉紀行,石田敦彦,亀下勇
    • Organizer
      日本生化学会中四国支部会
    • Place of Presentation
      高知
    • Related Report
      2008 Final Research Report
  • [Presentation] Knockdown of nuclear calcium/calmodulin-dependent protein kinase phosphatase causes developmental abnormalities in zebra fish2007

    • Author(s)
      Nimura, T., Sueyoshi, N.他
    • Organizer
      EuroPhosphatase2007"Protein Phosphatases in Health and Disease"
    • Place of Presentation
      Aveiro, Portugal
    • Related Report
      2007 Annual Research Report
  • [Presentation] 担子菌Coprinus cinereusの菌糸に発現する新規プロテインキナーゼの発現クローニングとその解析2007

    • Author(s)
      金子啓祐, 山田裕介, 杉山康憲, 末吉紀行他
    • Organizer
      2007年度日本農芸化学命中四国・西日本支部合同大会
    • Place of Presentation
      山口
    • Related Report
      2007 Annual Research Report
  • [Presentation] DNAメチルトランスフェラーゼ1 (Dnmtl)のN末端領域に結合するプロテインキナーゼの同定と解析2007

    • Author(s)
      関口茉里, 濱崎大介, 波多野直哉, 末吉紀行他
    • Organizer
      日本生化学会中四国支部例会
    • Place of Presentation
      高知
    • Related Report
      2007 Annual Research Report
  • [Presentation] Ca^<2+>/CaM依存性プロテインキナーゼホスフアターゼ(CaMKP)の各種変異体を用いた機能解析2007

    • Author(s)
      沼野琢旬, 多田幸代, 末吉紀行他
    • Organizer
      日本生化学会中四国支部例会
    • Place of Presentation
      高知
    • Related Report
      2007 Annual Research Report
  • [Presentation] ゼブラフィッシュCyc1in-dependent protein kinase like 5 (zCDKL5)のcDNAクローニングとノックダウン2007

    • Author(s)
      関口茉里, 末吉紀行他
    • Organizer
      第30回日本分子生物学会年会 第80回日本生化学会大会 合同大会
    • Place of Presentation
      横浜
    • Related Report
      2007 Annual Research Report
  • [Presentation] Catalytic properties of zebrafish Doublecortin-like protein kinase (zDCLK)2007

    • Author(s)
      下村幸子, 二村貴樹, 末吉紀行他
    • Organizer
      第30回日本分子生物学会年会 第80回日本生化学会大会 合同大会
    • Place of Presentation
      横浜
    • Related Report
      2007 Annual Research Report
  • [Presentation] 糖毒性状態のINS-1細胞においてCaMKIVがインスリン分泌を制御する2007

    • Author(s)
      杉山康憲, 村尾孝児, 井町仁美, 末吉紀行他
    • Organizer
      第30回日本分子生物学会年会 第80回日本生化学会大会 合同大会
    • Place of Presentation
      横浜
    • Related Report
      2007 Annual Research Report
  • [Presentation] S100タンパク質によるHsp70/Hsp90分子シヤペロン複合体の形成調節2007

    • Author(s)
      小池克英, 嶋本聖子, 末吉紀行他
    • Organizer
      第30回日本分子生物学会年会 第80回日本生化学会大会 合同大会
    • Place of Presentation
      横浜
    • Related Report
      2007 Annual Research Report
  • [Presentation] 縁談菌セラミダーゼの構造と機能の解析2007

    • Author(s)
      沖野望, 井上豪, 岡野浩幸, 上林浩二, 合田(問註所)初美, 谷元洋, 末吉紀行他
    • Organizer
      第30回日本分子生物学会年会 第80回日本生化学会大会 合同大会
    • Place of Presentation
      横浜
    • Related Report
      2007 Annual Research Report
  • [Presentation] DNA methyltransferase 1 (Dnmt1)のN末端領域にはCyclin-dependent protein kinase like 5 (CDKL5)が結合する2007

    • Author(s)
      濱崎大介, 関口茉里, 大下幸助, 波多野直哉, 徳田雅明, 末吉紀行他
    • Organizer
      第30回日本分子生物学会年会 第80回日本生化学会大会 合同大会
    • Place of Presentation
      横浜
    • Related Report
      2007 Annual Research Report
  • [Presentation] Ca^<2+>/CaM依存性プロテインキナーゼホスフアターゼ(CaMKP)阻害剤のスクリーニング2007

    • Author(s)
      沼野琢旬, 末吉紀行他
    • Organizer
      第30回日本分子生物学会年会 第80回日本生化学会大会 合同大会
    • Place of Presentation
      横浜
    • Related Report
      2007 Annual Research Report
  • [Presentation] ゼブラフィッシュ初期発生系を用いた酸性スフィンゴミェリナーゼの解析2007

    • Author(s)
      堀佑希, 吉村征浩, 末吉紀行他
    • Organizer
      第30回日本分子生物学会年会 第80回日本生化学会大会 合同大会
    • Place of Presentation
      横浜
    • Related Report
      2007 Annual Research Report
  • [Presentation] SAD-BのCaM-KKによるリン酸化と活性化2007

    • Author(s)
      藤本智仁, 揺本沙紀, 波多野直哉, 野崎直仁, 末吉紀行他
    • Organizer
      第30回日本分子生物学会年会 第80回日本生化学会大会 合同大会
    • Place of Presentation
      横浜
    • Related Report
      2007 Annual Research Report

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Published: 2007-04-01   Modified: 2016-04-21  

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