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Germ layer patterning and axis formation in the most basal ray-finned fish, Polypterus senegalus.

Research Project

Project/Area Number 19770202
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Developmental biology
Research InstitutionThe Institute of Physical and Chemical Research

Principal Investigator

TAKEUCHI Masaki  The Institute of Physical and Chemical Research, ボディプラン研究グループ, 研究員 (00392019)

Project Period (FY) 2007 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥3,720,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥420,000)
Fiscal Year 2008: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2007: ¥1,900,000 (Direct Cost: ¥1,900,000)
Keywords進化発生 / 初期発生 / 卵割 / 胚葉形成 / 内胚葉 / 脊椎動物 / ポリプテルス / ヤツメウナギ / 胚葉パターン形成 / 条鰭類 / VegT / 多様化 / 卵割様式 / sox17
Research Abstract

ポリプテルスは原始的な硬骨魚であり、脊椎動物の進化を探るうえで非常に重要な系統的位置を占める。その初期発生の様子は全割卵で両生類と類似し、盤割卵の真骨魚(一般的な進化した硬骨魚)とは様々な点で異なる。しかしながら、ポリプテルスは全割発生であるにも拘らず、植物極側細胞集団が胚葉に貢献しない点で両生類とも異なる。この特徴は、最も原始的な現生脊椎動物であるヤツメウナギでも保存されており、ポリプテルス様の初期発生機構は脊椎動物の祖先型と考えられる。

Report

(3 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • Research Products

    (16 results)

All 2009 2008 2007

All Journal Article (6 results) (of which Peer Reviewed: 3 results) Presentation (8 results) Book (2 results)

  • [Journal Article] Evolution of Otx paralogue usages in early patterning of the vertebrate head.2009

    • Author(s)
      Takeuchi, M. (7名中3番目)
    • Journal Title

      Developmental Biology 325

      Pages: 282-295

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] The Genus Polypterus (Bichirs) : A Fish Group Diverged at the Stem of Ray-Finned Fishes (Actinopterygii).2009

    • Author(s)
      Takeuchi, M., Okabe, M., Aizawa, S.
    • Journal Title

      Cold Spring Harb. Protoc. 5

    • Related Report
      2008 Final Research Report
  • [Journal Article] Microinjection of Bichir (Polypterus) Embryos.2009

    • Author(s)
      Takeuchi, M., Okabe, M., Aizawa, S.
    • Journal Title

      Cold Spring Harb. Protoc. 5

    • Related Report
      2008 Final Research Report
  • [Journal Article] Whole-Mount In Situ Hybridization of Bichir (Polypterus) Embryos.2009

    • Author(s)
      Takeuchi, M., Okabe, M., Aizawa, S.
    • Journal Title

      Cold Spring Harb. Protoc. 5

    • Related Report
      2008 Final Research Report
  • [Journal Article] Germ layer patterning in bichir and lamprey ; an insight into its evolution in vertebrates.2009

    • Author(s)
      Takeuchi, M., Takahashi, M., Okabe, M., Aizawa, S.
    • Journal Title

      Developmental Biology (in press)

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Evolution of Otx paralogue usages in early patterning of the vertebrate head2008

    • Author(s)
      Yoko Suda, Daisuke Kurokawa, Masaki Takeuchi, Eriko Kajikawa, Shigeru Kuratani, Chris Amemiya, Shinichi Aizawa
    • Journal Title

      Developmental Biology 325

      Pages: 282-295

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Presentation] ポリプテルス、ヤツメウナギの全割発生にみる部分割発生の進化的起源2008

    • Author(s)
      Masaki Takeuchi(代表)
    • Organizer
      第14回小型魚類研究会
    • Place of Presentation
      岡崎コンファレンスセンター(基礎生物学研究所)
    • Year and Date
      2008-09-20
    • Related Report
      2008 Final Research Report
  • [Presentation] Holoblastic Embryogenesis in a Basal Actinopterygian and Lamprey Represents the State as Evolutionary Origin of Meroblastic it2008

    • Author(s)
      Masaki Takeuchi, Maiko Takahashi, Shinichi Aizawa
    • Organizer
      第14回小型魚類研究会
    • Place of Presentation
      愛知県岡崎市コンファレンスセンター
    • Related Report
      2008 Annual Research Report
  • [Presentation] 原始的条鰭類ポリプテルスからみる脊椎動物初期発生の多様化とその分子機構2007

    • Author(s)
      竹内 雅貴(代表)
    • Organizer
      BMB2007(第30回日本分子生物学会年会・第80回日本生化学会大会 合同大会)
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2007-12-11
    • Related Report
      2008 Final Research Report
  • [Presentation] 原始的条鰭類ポリプテルスからみる脊椎動物初期発生の多様化とその分子機構2007

    • Author(s)
      竹内 雅貴
    • Organizer
      日本分子生物学会(日本生化学会と合同)
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2007-12-11
    • Related Report
      2007 Annual Research Report
  • [Presentation] 原始的条鰭類ポリプテルスの胚葉パターンと原腸形成2007

    • Author(s)
      竹内 雅貴(代表)
    • Organizer
      原始的条鰭類ポリプテルスの胚葉パターンと原腸形成
    • Place of Presentation
      東京大学
    • Year and Date
      2007-09-16
    • Related Report
      2008 Final Research Report
  • [Presentation] 祖先的条鰭類ポリプテルスの初期発生 : 両生類/真骨魚との比較と考察2007

    • Author(s)
      竹内 雅貴(代表)
    • Organizer
      第40回日本発生生物学会・第59回日本細胞生物学会大会 合同大会
    • Place of Presentation
      福岡国際会議場
    • Year and Date
      2007-05-30
    • Related Report
      2008 Final Research Report
  • [Presentation] Research of early embryogenesis in the most ancestral ray-finned fish, Polypterus senegalus2007

    • Author(s)
      竹内 雅貴
    • Organizer
      日本発生生物学会(日本細胞生物学会と合同)
    • Place of Presentation
      福岡国際会議場
    • Year and Date
      2007-05-30
    • Related Report
      2007 Annual Research Report
  • [Presentation] 原始的条鰭類ポリプテルスの胚葉パターンと原腸形成2007

    • Author(s)
      竹内 雅貴
    • Organizer
      第13回小型魚類研究会
    • Place of Presentation
      東京大学小柴ホール 同 山上会館
    • Year and Date
      2007-05-30
    • Related Report
      2007 Annual Research Report
  • [Book] Emerging Model Organisms Vol. 1, In: Gann, A., Crotty, D. (Eds), Chapter 18 ; The Genus Polypterus (Bichir) ; A Fish Group Diverged at the Stem of Ray-finned Fishes (Actinopterygii).2008

    • Author(s)
      Takeuchi, M., Takahashi, M., Okabe, M., Aizawa, S.
    • Publisher
      Cold Spring Harbor Laboratory Press
    • Related Report
      2008 Final Research Report
  • [Book] Emerging Model Organisms Vol. 1, Chapter 18 The Genus Polypterus (Bichir) ; A Fish Group Diverged at the Stem of Ray-finned Fishes (Actihopterygii)2008

    • Author(s)
      Masaki Takeuchi, Masataka Okabe, Shinichi Aizawa
    • Total Pages
      21
    • Publisher
      Cold Spring Harbor Laboratory Press
    • Related Report
      2008 Annual Research Report

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Published: 2007-04-01   Modified: 2016-04-21  

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