| Budget Amount *help |
¥3,800,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥600,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2008: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2007: ¥1,200,000 (Direct Cost: ¥1,200,000)
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| Research Abstract |
RNA interference (RNAi)-based therapy with small interfering RNA (siRNA) is expected as a potent treatment strategy for intractable diseases. However, systemic injection of siRNA is quite limited because of a problem of DDS technology. In the present study, a novel siRNA delivery system was established to achieve RNAi-based cancer therapies. Our data demonstrated that systemic injection of therapeutic siRNAs using our DDS technology suppressed tumor growth in animal studies.
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