The role of Dlg in neural crest development.
| Project/Area Number |
19790158
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
General anatomy (including Histology/Embryology)
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| Research Institution | Fujita Health University |
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Principal Investigator |
KOGO Akiko Fujita Health University, 医学部, 助教 (20340242)
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| Project Period (FY) |
2007 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
|
| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥570,000)
Fiscal Year 2009: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2008: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2007: ¥1,300,000 (Direct Cost: ¥1,300,000)
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| Keywords | 発生学 / 形態形成学 / 神経堤 / Dlg / 発生・分化 / 心臓 / 心臓流出路 / ノックアウトマウス / 胸骨 / 骨形成 |
|---|
| Research Abstract |
Dlg is thought to be a scaffolding protein, which links proteins attached to plasma membrane. Cardiac neural crest cells are known to be involved in the morphogenesis of the heart and outflow tracts. Dlg gene-targeted mice exhibit severe developmental defects in outflow tracts and ventricular septum. We evaluated the possibility that Dlg is involoved in the neural crest development.
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Report
(4 results)
Research Products
(30 results)
