Analysis of amplification and overexpression of EGFR, Her2/neu in malignant pleural mesothelioma
Project/Area Number |
19790250
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Single-year Grants |
Research Field |
Human pathology
|
Research Institution | Chiba University |
Principal Investigator |
YONEMORI Yoko Chiba University, 大学院・医学研究院, 助教 (10422247)
|
Project Period (FY) |
2007 – 2008
|
Project Status |
Completed (Fiscal Year 2008)
|
Budget Amount *help |
¥3,390,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥390,000)
Fiscal Year 2008: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2007: ¥1,700,000 (Direct Cost: ¥1,700,000)
|
Keywords | 呼吸器 / 胸膜悪性中皮腫 / FISH / HER2 / neu / EGFR |
Research Abstract |
Overexpression of the EGFR proteins and ErbB-2 proteins were examined by immunohistochemistry in seventeen malignant pleural mesothelioma. Overexpression of ErbB-2 was found in 11.7% of tumors and was not associated with gene amplification. Overexpression of EGFR was found in 5.8% of tumors and was not associated with gene amplification.
|
Report
(3 results)
Research Products
(1 results)