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Nested case-control study to clarify preventive factors of prostate cancer. ???

Research Project

Project/Area Number 19790414
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Hygiene
Research InstitutionNational Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East

Principal Investigator

KURAHASHI Norie  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East, 予防研究部, 研究員 (00446551)

Project Period (FY) 2007 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥3,660,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥360,000)
Fiscal Year 2008: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2007: ¥2,100,000 (Direct Cost: ¥2,100,000)
Keywords予防医学 / がん疫学 / 前立腺がん / イソフラボン / 癌
Research Abstract

1990年と1993年から開始されているコホートにおける、40歳以上70歳未満(調査開始時年齢)の男性を対象とし、コホート内症例対照研究を行った。2004年末までの追跡期間中に前立腺がんを発症した201名とその対照の402名の、コホート研究開始時の血液サンプルについて、血漿中イソフラボン類の値を比較した。その結果、イソフラボンは限局前立腺がんリスクの低下に関連することが示唆された。

Report

(3 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • Research Products

    (12 results)

All 2009 2008 2007 Other

All Journal Article (5 results) (of which Peer Reviewed: 5 results) Presentation (4 results) Remarks (3 results)

  • [Journal Article] Plasma isoflavones and subsequent risk of prostate cancer in a nested case-control study: the Japan Public Health Center2008

    • Author(s)
      Kurahashi N, Iwasaki M, Inoue M, Sasazuki S, Tsugane S.
    • Journal Title

      J Clin Oncol 26

      Pages: 5923-9

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Plasma isoflavones and subsequent risk of prostate cancer in a nested case-control study : the Japan Public Health Center.2008

    • Author(s)
      Kurahashi N, et al.
    • Journal Title

      J Clin Oncol. 26

      Pages: 5923-9

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Green tea consumption and prostate cancer risk in Japanesemen:a prospective study2008

    • Author(s)
      Kurahashi, et. al.
    • Journal Title

      Am J Epidemiol 167

      Pages: 71-77

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Dairy Product, Saturated Fatty Acid, and Calcium Intake and Prostate Cancer in a Prospective Cohort of Japanese Men2008

    • Author(s)
      Kurahashi, et. al.
    • Journal Title

      Cancer Epidemiol Biomarkers Prev 17

      Pages: 930-937

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Soy product and isoflavone consumption in relation to prostate cancer in Japanese men2007

    • Author(s)
      Kurahashi N, Iwasaki M, Sasazuki S, Otani T, Inoue M, Tsugane S
    • Journal Title

      Cancer Epidemiol Biomarkers Prev 16

      Pages: 538-45

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Presentation] 血中イソフラボン濃度と前立腺がん罹患リスクとの関連:厚生労働省研究班による多目的コホート研究より2009

    • Author(s)
      倉橋典絵、岩崎基、井上真奈美、笹月静、津金昌一郎
    • Organizer
      第19回 日本疫学会学術総会
    • Place of Presentation
      金沢市
    • Year and Date
      2009-01-24
    • Related Report
      2008 Final Research Report
  • [Presentation] 血中イソフラボン濃度と前立腺がん罹患リスクとの関連 : 厚生労働省研究班による多目的コホート研究より2009

    • Author(s)
      倉橋典絵
    • Organizer
      第19回日本疫学会学術総会
    • Place of Presentation
      金沢市
    • Year and Date
      2009-01-24
    • Related Report
      2008 Annual Research Report
  • [Presentation] 緑茶摂取と前立腺がん罹患リスクとの関連2008

    • Author(s)
      倉橋 典絵
    • Organizer
      第18回日本疫学会学術総会
    • Place of Presentation
      東京
    • Year and Date
      2008-01-26
    • Related Report
      2007 Annual Research Report
  • [Presentation] 大豆製品・イソフラボン摂取量と前立腺がんとの関連2007

    • Author(s)
      倉橋典絵、岩崎基、笹月静、大谷哲也、井上真奈美、津金昌一郎
    • Organizer
      がん予防大会
    • Place of Presentation
      東京都
    • Year and Date
      2007-07-13
    • Related Report
      2008 Final Research Report
  • [Remarks] ホームページ等

    • URL

      http://epi.ncc.go.jp/jphc/index.html

    • Related Report
      2008 Final Research Report
  • [Remarks]

    • URL

      http://epi.ncc.go.jp/jphc/index.html

    • Related Report
      2008 Annual Research Report
  • [Remarks]

    • URL

      http://epi.ncc.go.jp/jphc/index.html

    • Related Report
      2007 Annual Research Report

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Published: 2007-04-01   Modified: 2016-04-21  

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