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A functional analysis of HGF-induced Npn3, that is the candidate of the anti-apoptostic molecule

Research Project

Project/Area Number 19790488
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Gastroenterology
Research InstitutionKagoshima University

Principal Investigator

MORIUCHI Akihiro  Kagoshima University, 医学部・歯学部附属病院, 助教 (40359823)

Project Period (FY) 2007 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥3,660,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥360,000)
Fiscal Year 2008: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2007: ¥2,100,000 (Direct Cost: ¥2,100,000)
Keywords肝臓病学 / npn3 / HGF / アポトーシス
Research Abstract

HGF特異的に発現誘導される遺伝子としてnpn3を同定した。さらに、human npn3の発現ベクターを構築し、培養細胞へ遺伝子導入することでアポトーシス誘導に対して抵抗性を獲得することを確認した。

Report

(3 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • Research Products

    (2 results)

All 2007

All Presentation (2 results)

  • [Presentation] 網羅的遺伝子発現解析を用いたHGFの抗アポトーシス機構の解明2007

    • Author(s)
      森内昭博、井戸章雄、山路尚久、瀬戸山仁、重信秀峰、小原一憲、沼田政嗣、長谷川将、宇都浩文、桶谷真、坪内博仁
    • Organizer
      第43回日本肝臓学会総会
    • Place of Presentation
      東京
    • Year and Date
      2007-06-01
    • Related Report
      2008 Final Research Report
  • [Presentation] 網羅的遺伝子発現解析を用いたHGFの抗アポトーシス機構の解明2007

    • Author(s)
      森内 昭博
    • Organizer
      第43回 日本肝臓学会 総会
    • Place of Presentation
      東京
    • Year and Date
      2007-06-01
    • Related Report
      2007 Annual Research Report

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Published: 2007-04-01   Modified: 2016-04-21  

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