| Budget Amount *help |
¥4,969,235 (Direct Cost: ¥4,076,335、Indirect Cost: ¥892,900)
Fiscal Year 2010: ¥1,139,235 (Direct Cost: ¥876,335、Indirect Cost: ¥262,900)
Fiscal Year 2009: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2008: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2007: ¥1,100,000 (Direct Cost: ¥1,100,000)
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| Research Abstract |
The distribution and ultrastructure of the interstitial cells of Cajal (ICC) has been examined in the guinea-pig ileocaecal junction including the valve. In the ileocaecal junction, ICC showed a dense distribution in close association with the nerves. In addition, ICC were observed around the submucosal plexus (ICC-SP). ICC-SP shared ultrastructural criteria with ICC in the tunica muscularis and expressed the neurokinin 1 receptor(NK1-R). These observations appear to provide morphological evidence that ICC including ICC-SP play an important role in the movement of the junctional area.
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