Left atrial volume predicts cardiovascular events in a cohort of Japanese patients
Project/Area Number |
19790544
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Single-year Grants |
Research Field |
Circulatory organs internal medicine
|
Research Institution | Kansai Medical University |
Principal Investigator |
MIYASAKA Yoko Kansai Medical University, 医学部, 講師 (10343675)
|
Project Period (FY) |
2007 – 2010
|
Project Status |
Completed (Fiscal Year 2010)
|
Budget Amount *help |
¥1,090,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥90,000)
Fiscal Year 2010: ¥130,000 (Direct Cost: ¥100,000、Indirect Cost: ¥30,000)
Fiscal Year 2009: ¥130,000 (Direct Cost: ¥100,000、Indirect Cost: ¥30,000)
Fiscal Year 2008: ¥130,000 (Direct Cost: ¥100,000、Indirect Cost: ¥30,000)
Fiscal Year 2007: ¥700,000 (Direct Cost: ¥700,000)
|
Keywords | 左室拡張能障害 / 心房細動 / 脳梗塞 / 心エコー / 肥満 |
Research Abstract |
Left atrial (LA) enlargement has been shown to be risk factors for cardiovascular morbidity. There is a paucity of data as to whether LA volume predicts cardiovascular events in a cohort of Japanese patients. Adult patients referred for echocardiogram were prospectively included. Cardiovascular events were ascertained using Framingham criteria. Cox-proportional hazards modeling was used. Of 1,102 patients (mean 61±15 year-old, 50% men), 40 (4%) developed cardiovascular events during mean follow-up of 19±14 months. In a multivariate model, greater indexed LA volume was an independent predictor of cardiovascular events (HR=1.4, 95%CI=1.1-1.7, P=0.001). In addition to traditional risk factors for atherosclerosis, LA size appears to be independent risk for cardiovascular events, which provides clinically meaningful prognostic information..
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Report
(6 results)
Research Products
(24 results)