A Role of Butyrophilin Like 2 as New Co-stimulatory Molecule in Antigen-specific IgE Responsiveness

• Project/Area Number: 19790550
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Respiratory organ internal medicine
• Research Institution: Aichi Medical University
• Principal Investigator: TAKAHASHI Daisuke Aichi Medical University, 医学部, 助教 (00431370)
• Project Period (FY): 2007 – 2008
• Project Status: Completed (Fiscal Year 2008)
• Budget Amount: ¥3,690,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥390,000); Fiscal Year 2008: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000); Fiscal Year 2007: ¥2,000,000 (Direct Cost: ¥2,000,000)
• Keywords: ブチロフィリンライク2 / 6P21 / アレルギー / 一塩基多型 / ハプロタイプ / 連鎖不平衡 / ダニ抗原特異的IgE応答 / アミノ酸変異 / 6p21

Research Abstract

ブチロフィリンライク2(BTNL2)はダニ抗原特異的IgE応答に関与する遺伝子の一つである可能性があることを初めて報告できた.

Research Products

• [Journal Article] Genetic Impact of a Butyrophilin-like 2 (BTNL2) Gene Variation on Specific IgE Responsiveness to Dermatophagoides farinae (Der f) in Japanese. (2009)
  • Author(s): S Konno, D Takahashi, N Hizawa, et al.
  • Journal Title: Allergology International 58 Pages: 29-35
  • NAID: 10025109005
  • Peer Reviewed
• [Journal Article] Genetic Impact of a Butyrophilin-like 2 (BTNL2) Gene Variation on Specific IgE Responsiveness to Dermatophagoides farina (Der f) in Japanese (2009)
  • Author(s): S Konno, D Takahashi, N Hizawa, et.al.
  • Journal Title: Allergology International 58 Pages: 29-35
  • NAID: 10025109005
  • Peer Reviewed