The role of Sphingosine 1-phosphate(S1P)/S1P1 Signaling in the Osteoclastogenesis.
| Project/Area Number |
19790699
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
膠原病・アレルギー・感染症内科学
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| Research Institution | Hyogo College of Medicine |
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Principal Investigator |
KITANO Masayasu Hyogo College of Medicine, 医学部, 助教 (00412031)
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| Project Period (FY) |
2007 – 2008
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| Project Status |
Completed (Fiscal Year 2008)
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| Budget Amount *help |
¥3,550,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥450,000)
Fiscal Year 2008: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2007: ¥1,600,000 (Direct Cost: ¥1,600,000)
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| Keywords | スフィンゴシン1リン酸(S1P) / 破骨細胞 / 関節リウマチ(RA) / スフィンゴシン1-リン酸 / 関節リウマチ / RANKL |
|---|
| Research Abstract |
スフィンゴシン1リン酸は、関節リウマチ(RA)滑膜細胞でのRANKL発現を増強することによりRAでの骨破壊に促進的に作用する。
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Report
(3 results)
Research Products
(14 results)
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[Presentation] The role of sphingosine 1-Phosphate/S1P1 signaling in the osteoclastogenesis via RANKL expression of rheumatoid synoviocytes2008
Author(s)
Kitano, M., Takeshita, H., Tsunemi, S., Kitano, S., Sekiguchi, M., Nishioka,A., Azuma, N., Hashimoto,N., Iwasaki,T., Hla, T and Sano, H
Organizer
Annual European Congress of Rheumatology (EULAR2008)
Place of Presentation
Paris,France
Year and Date
2008-06-13
Related Report
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[Presentation] Treatment of a murine arthritis midel, SKG mouse, by FTY720 a new immunosuppressant2008
Author(s)
Tsunemi, S., Iwasaki, T., Kitano, M., Seki guchi, M, Kitano, S., Imado, T. and Sano, H
Organizer
Annual European Congress of Rheumatology (EULAR2008)
Place of Presentation
Paris,France
Year and Date
2008-06-13
Related Report
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[Presentation] Th17 and Foxp3 regulatory T cells(Tregs) in primary Sjogren's Syndrome (SS) : role of Sphingosine 1-phosphate (S1P)2008
Author(s)
Sekiguchi, M., Iwasaki, T., Kitano, M., Ha shimoto, N., Kitano, S., Hla, T and Sano, H
Organizer
The 72th Annual Scientific Meeting of the American College of Rheumatology
Place of Presentation
SanFrancisco, U.S.A.
Related Report
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[Presentation] 炎症性サイトカインはリウマチ滑膜細胞でのスフィンゴシン1燐酸/スフィンゴシン1燐酸レセプター1シグナルを増強する2008
Author(s)
北野将康,関口昌弘,常見幸,神田ちえり,西岡亜紀,東直人,黒岩孝則,橋本尚明,松井聖,岩崎剛,佐野統
Organizer
第52回日本リウマチ学会総会・学術集会(JCR2008)
Place of Presentation
札幌
Related Report
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