Pathophysiology and Hemodynamics of Cerebral aneurysms
Project/Area Number |
19791010
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Single-year Grants |
Research Field |
Cerebral neurosurgery
|
Research Institution | The University of Tokyo (2009) Jichi Medical University (2007-2008) |
Principal Investigator |
SHOJIMA Masaaki Jichi Medical University, 医学部附属病院, 助教 (80376425)
|
Project Period (FY) |
2007 – 2009
|
Project Status |
Completed (Fiscal Year 2009)
|
Budget Amount *help |
¥3,600,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2008: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2007: ¥1,000,000 (Direct Cost: ¥1,000,000)
|
Keywords | 脳動脈瘤 / 血行力学 / 流体力学 / シミュレーション / 血行力学的ストレス / せん断応力 / アテローム硬化 / 脳神経外科 / 脳血管内外科学 / 医用工学 |
Research Abstract |
In this research, 82 unruptured cerebral aneurysms were followed with catheter-based 3D rotational angiography, and among them, blister formation was documented in 4 aneurysm during the 10.1 months observation. Three of them could be analyzed here to characterize the hemodynamic features associated with the blister formation. Blister formation occurred at the area of low shear magnitude and high shear gradient. Our findings would contribute to reveal the hemodynamic features leading to the aneurysm progression and provide the basis of the aneurysm treatment via flow alteration.
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Report
(4 results)
Research Products
(19 results)