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Visualization of sensation abnormality by examinations of somatosensory evoked magnetic fields

Research Project

Project/Area Number 19791033
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Orthopaedic surgery
Research InstitutionHiroshima University

Principal Investigator

NAKANISHI Kazuyoshi  Hiroshima University, 病院, 病院助教 (60403557)

Project Period (FY) 2007 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥3,710,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥510,000)
Fiscal Year 2008: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2007: ¥1,500,000 (Direct Cost: ¥1,500,000)
Keywords体性感覚 / 脳磁図 / 異常感覚 / 痛み / 感覚障害
Research Abstract

我々は手指の機械受容器刺激装置を独自に開発し,機械受容器刺激後の体性感覚野の信号処理のプロセスを可視化することに成功した.また,動物実験モデルを用い,神経障害と修復における電気生理学的な機能評価を行った.また,臨床研究として,四肢の異常感覚を有する脊髄障害に関連する電気生理学的研究を行った.今後さらに感覚障害の程度あるいは障害の特性の違いにおける体性感覚野の反応についての研究をすすめる予定である.

Report

(3 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • Research Products

    (45 results)

All 2009 2008 2007 Other

All Journal Article (18 results) (of which Peer Reviewed: 11 results) Presentation (27 results)

  • [Journal Article] The response of the human cerebral somatosensory cortex to mechanical stimulation2008

    • Author(s)
      Inoue K, Nakanishi K, Hashizume A, Ochi M, Matsumoto M.
    • Journal Title

      Clinical Neurophysiology 119

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Modulation of the secondary injury process after spinal cord injury in Bach1-deficient mice by heme oxygenase-1.2008

    • Author(s)
      Yamada K, Tanaka N, Nakanishi K, Kamei N, Ishikawa M, Toshiyuki M, Igarashi K, Ochi M
    • Journal Title

      Journal of Neurosurgery: Spine 9

      Pages: 611-620

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Modulation of the secondary injury process after spinal cord injury in Bach 1-deficient mice by heme oxygenase-12008

    • Author(s)
      Yamada K
    • Journal Title

      Journal of Neurosurgery : Spine 9

      Pages: 611-620

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] マウス脊髄損傷モデルにおける酸化ストレスの影響-運動誘発電位測定による検討-2007

    • Author(s)
      山田清貴,田中信弘,中西一義,佐々木浩文,西田幸司,亀井直輔,當天賢子,濱崎貴彦,越智光夫
    • Journal Title

      脊髄機能診断学 28

      Pages: 47-52

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Significant correlation between corticospinal tract conduction block and prolongation of central motor conduction time in compressive cervical myelopathy2007

    • Author(s)
      Nakanishi K, Tanaka N, Kamei N, Hamasaki T, Nishida K, Touten Y, Ochi M
    • Journal Title

      J Neurol Sci. 256(1-2)

      Pages: 71-4

    • NAID

      40016971464

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] 機械的刺激による人間の大脳皮質体性感覚野の反応2007

    • Author(s)
      井上健,中西一義,橋詰顕
    • Journal Title

      臨床神経生理学 35

      Pages: 412-413

    • Related Report
      2008 Final Research Report
  • [Journal Article] HomeOxygenase-1の抗酸化作用による脊髄機能保護Bach1ノックアウトマウスを用いた検討(第2報)2007

    • Author(s)
      山田清貴
    • Journal Title

      日本整形外科学会雑誌 81巻8号

      Pages: 945-945

    • Related Report
      2007 Annual Research Report
  • [Journal Article] 頸部圧迫性脊髄症における中枢運動伝導時間延長と脊髄誘発電位所見との関連2007

    • Author(s)
      中西一義
    • Journal Title

      日本整形外科学会雑誌 81巻8号

      Pages: 925-925

    • Related Report
      2007 Annual Research Report
  • [Journal Article] 脊髄硬膜動静脈瘻に対する運動誘発電位、F波測定による機能評価2007

    • Author(s)
      中西一義
    • Journal Title

      日本整形外科学会雑誌 81巻4号

      Pages: 410-410

    • Related Report
      2007 Annual Research Report
  • [Journal Article] 頸椎椎弓形成術後の上肢麻痺に関する前向き研究術中運動誘発電位モニタリングの試み2007

    • Author(s)
      田中信弘
    • Journal Title

      日本整形外科学会雑誌 81巻4号

      Pages: 368-368

    • Related Report
      2007 Annual Research Report
  • [Journal Article] 機械的刺激による人間の大脳皮質体性感覚野の反応2007

    • Author(s)
      井上健
    • Journal Title

      臨床神経生理学 35巻5号

      Pages: 412-413

    • Related Report
      2007 Annual Research Report
  • [Journal Article] Significant correlation between corticospinal tract conduction block and prolongation of central motor conduction time in compressive cervical myelopathy.2007

    • Author(s)
      Nakanishi K
    • Journal Title

      J Neurol Sci. 256(1-2)

      Pages: 71-4

    • NAID

      40016971464

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] マウス脊髄損傷モデルにおける酸化ストレスの影響-運動誘発電位測定による検討-2007

    • Author(s)
      山田清貴
    • Journal Title

      脊髄機能診断学 28巻(1号)

      Pages: 47-52

    • Related Report
      2007 Annual Research Report
  • [Journal Article] Ochi M Human cerebral somatosensory cortex response to mechanical stimulation using a new non-magnetic device.

    • Author(s)
      Hikmat H, Inoue K, Nakanishi K, Kurumadani H, Sunagawa T
    • Journal Title

      Clinical Neurophysiology (In press)

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Preoperative electrophysiological assessments by motor evoked potentials in elderly patients with compressive cervical myelopathy.

    • Author(s)
      Yamada K, Tanaka N, Nakanishi K, Sasaki H, Ochi M
    • Journal Title

      The Journal of the Japanese Society for Spine Surgery and Related Research (In press)

    • NAID

      10025188665

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Preoperative electrophysiological assessments by motor evoked potentials in elderly patients with compressive cervical myelopathy

    • Author(s)
      Yamada K
    • Journal Title

      The Journal of the Japanese Society for Spine Surgery and Related Research (In press)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Human cerebral somatosensory cortex response to mechanical stimulation using a new non-magnetic device

    • Author(s)
      Hikmat H
    • Journal Title

      Clinical Neurophysiology (In press)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The response in the human cerebral somatosensory cortex to the mechanical stimulation

    • Author(s)
      Ken Inoue
    • Journal Title

      Clinical Neurophysiology (In press)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Presentation] 頚部圧迫性脊髄症における中枢運動伝導時間が延長する機序2009

    • Author(s)
      中西一義,田中信弘,佐々木浩文,山田清貴,山本りさこ,中前稔生,泉文一郎,藤本吉範,越智光夫
    • Organizer
      第31回脊髄機能診断研究会
    • Place of Presentation
      東京都
    • Year and Date
      2009-02-07
    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Presentation] Heme Oxygenase-1 Modulates the Secondary Injury Process after Spinal Cord Injury in Bach1 Deficient Mice2009

    • Author(s)
      Yamada K, Tanaka N, Nakanishi K, Sasaki H, Kamei N, Hamasaki T, Ishikawa M, Yamamoto R, Nakamae T, Izumi B, Ochi M
    • Organizer
      55th. Annual Meeting of the Orthopaedic Research Society
    • Place of Presentation
      Las Vegas, NV.
    • Related Report
      2008 Final Research Report
  • [Presentation] Heme Oxygenase-1 Modulates the Secondary Injury Process after Spinal Cord Injury in Bach 1 Deficient Mice2009

    • Author(s)
      Yamada K
    • Organizer
      55th Annual Meeting of the Orthopaedic Research Society
    • Place of Presentation
      Las Vegas, NV USA
    • Related Report
      2008 Annual Research Report
  • [Presentation] SPINAL FUNCTION IS PRESERVED AFTER SPINAL CORD INJURY IN BACH1 DEFICIENT MICE, 54th.2008

    • Author(s)
      Yamada K, Tanaka N, Nakanishi K, Sasaki H, Kamei N, Hamasaki T, Yamamoto R, Nakamae T, Ochi M
    • Organizer
      Annual Meeting of the Orthopaedic Research Society
    • Place of Presentation
      San Francisco, USA.
    • Year and Date
      2008-03-02
    • Related Report
      2008 Final Research Report
  • [Presentation] SPINAL FUNCTION IS PRESERVED AFTER SPINAL CORD INJURY IN BACH1 DEFICIENT MICE2008

    • Author(s)
      Yamada K
    • Organizer
      54th Annual Meeting of the Orthopaedic Research Society
    • Place of Presentation
      San Francisco, U.S.A
    • Year and Date
      2008-03-02
    • Related Report
      2007 Annual Research Report
  • [Presentation] 機械的刺激による人間の大脳皮質体性感覚野の反応2008

    • Author(s)
      井上健,中西一義,Hikmat Hadoush,車谷洋,橋詰顕,砂川融,越智光夫
    • Organizer
      第38 回日本臨床神経生理学会・学術大会
    • Place of Presentation
      神戸市
    • Related Report
      2008 Final Research Report
  • [Presentation] Ochi M Human cerebral somatosensory cortex response to mechanical stimulation using a new non-magnetic device2008

    • Author(s)
      Hikmat H, Inoue K, Nakanishi K, Kurumadani H, Sunagawa T
    • Organizer
      第38回日本臨床神経生理学会・学術大会
    • Place of Presentation
      神戸市
    • Related Report
      2008 Final Research Report
  • [Presentation] Heme oxygenase-1による脊髄損傷後の二次損傷の軽減-Bach1 ノックアウトマウスを用いた電気生理学的検討-2008

    • Author(s)
      山田清貴, 田中信弘, 中西一義, 佐々木浩文, 亀井直輔, 濱崎貴彦, 石川正和, 山本りさこ, 中前稔生, 越智光夫
    • Organizer
      第23回日本整形外科学会基礎学術集会
    • Place of Presentation
      京都市
    • Related Report
      2008 Final Research Report
  • [Presentation] Spinal Function is Preserved after Spinal Cord Injury in Bach1 Deficient Mice.2008

    • Author(s)
      Yamada K, Tanaka N, Nakanishi K, Sasaki H, Kamei N, Hamasaki T, Ochi M.
    • Organizer
      24th. Annual meeting of the European Section of the Cervical Spine Research Society
    • Place of Presentation
      Geneva, Switzerland
    • Related Report
      2008 Final Research Report
  • [Presentation] Ochi M FUNCTIONAL EVALUATION WITH MOTOR EVOKED POTENTIALS FOLLOWING TRANSCRANIAL STIMULATION FOR COMPRESSIVE THORACIC MYELOPATHY2008

    • Author(s)
      Nakanishi K, Tanaka N, Fujimoto Y, Sasaki H, Yamada K, Yamamoto R, Nakamae T,
    • Organizer
      SPINE WEEK 2008 EURO SPINE
    • Place of Presentation
      Geneva, Switzerland
    • Related Report
      2008 Final Research Report
  • [Presentation] 胸椎部脊髄症診断における経頭蓋磁気刺激を用いた運動誘発電位計測の有用性2008

    • Author(s)
      中西一義,田中信弘,佐々木浩文,山田清貴,山本りさこ,中前稔生,越智光夫
    • Organizer
      第81回日本整形外科学会学術総会
    • Place of Presentation
      札幌市
    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Presentation] 高齢者頚髄症に対する運動誘発電位を用いた術前脊髄機能評価2008

    • Author(s)
      山田清貴, 田中信弘, 中西一義, 佐々木浩文,山本りさこ, 中前稔生, 越智光夫
    • Organizer
      第37回日本脊椎脊髄病学会
    • Place of Presentation
      東京都
    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Presentation] 頚椎部・胸椎部脊髄症診断における経頭蓋磁気刺激を用いた運動誘発電位計測の有用性2008

    • Author(s)
      中西一義
    • Organizer
      第37回日本脊椎脊髄病学会
    • Place of Presentation
      東京都
    • Related Report
      2008 Annual Research Report
  • [Presentation] Functional evaluation with motor evoked potentials following transcranial stimulation for compressive thoracic myelopathy2008

    • Author(s)
      Nakanishi K
    • Organizer
      SPINE WEEK 2008 EURO SPINE
    • Place of Presentation
      Geneva, Switzerland
    • Related Report
      2008 Annual Research Report
  • [Presentation] Spinal Function is Preserved after Spinal Cord Injury in Bach 1 Deficient Mice2008

    • Author(s)
      Yamada K
    • Organizer
      24th Annual meeting of the European Section of the Cervical Spine Research Society
    • Place of Presentation
      Geneva, Switzerland
    • Related Report
      2008 Annual Research Report
  • [Presentation] Heme oxygenase-1による脊髄損傷後の二次損傷の軽減-Bach 1ノックアウトマウスを用いた電気生理学的検討-2008

    • Author(s)
      由田清貴
    • Organizer
      第23回日本整形外科学会基礎学術集会
    • Place of Presentation
      京都市
    • Related Report
      2008 Annual Research Report
  • [Presentation] Human cerebral somatosensory cortex response to mechanical stimulation using a new non-magnetic device2008

    • Author(s)
      Hikmat H
    • Organizer
      第38回日本臨床神経生理学会・学術大会
    • Place of Presentation
      神戸市
    • Related Report
      2008 Annual Research Report
  • [Presentation] 機械的刺激による人間の大脳皮質体性感覚野の反応2008

    • Author(s)
      井上健
    • Organizer
      第38回日本臨床神経生理学会・学術大会
    • Place of Presentation
      神戸市
    • Related Report
      2008 Annual Research Report
  • [Presentation] Heme Oxygenase-1の抗酸化作用による脊髄機能保護-Bach1ノックアウトマウスを用いた検討・第2報-2007

    • Author(s)
      山田清貴,田中信弘,中西一義,亀井直輔,石川正和,越智光夫
    • Organizer
      第22回日本整形外科学会基礎学術集会
    • Place of Presentation
      浜松市
    • Year and Date
      2007-10-25
    • Related Report
      2008 Final Research Report
  • [Presentation] Home Oxygenase-1の抗酸化作用による脊髄機能保護Bach1ノックアウトマウスを用いた検討(第2報)2007

    • Author(s)
      山田清貴,田中信弘,中西一義,亀井直輔,石川正和,越智光夫
    • Organizer
      第22回日本整形外科学会基礎学術集会
    • Place of Presentation
      浜松市
    • Year and Date
      2007-10-25
    • Related Report
      2008 Final Research Report
  • [Presentation] HemeOxygenase-1の抗酸化作用による脊髄機能保護-Bach1ノックアウトマウスを用いた検討・第2報-2007

    • Author(s)
      山田清貴
    • Organizer
      第22回日本整形外科学会基礎学術集会
    • Place of Presentation
      浜松市
    • Year and Date
      2007-10-25
    • Related Report
      2007 Annual Research Report
  • [Presentation] 頸胸椎後縦靱帯骨化症に対する脊髄機能モニタリング下後方手術2007

    • Author(s)
      中西一義,田中信弘,藤本吉範,西川公一郎,山田清貴,越智光夫
    • Organizer
      第109回中部日本整形外科災害外科学会
    • Place of Presentation
      奈良市
    • Year and Date
      2007-10-04
    • Related Report
      2008 Final Research Report 2007 Annual Research Report
  • [Presentation] 高齢者頚髄症に関する電気生理学的検討2007

    • Author(s)
      山田清貴,田中信弘,中西一義,西田幸司,亀井直輔,越智光夫
    • Organizer
      第108回中部日本整形外科災害外科学会・学術集会
    • Place of Presentation
      広島市
    • Year and Date
      2007-04-13
    • Related Report
      2008 Final Research Report 2007 Annual Research Report
  • [Presentation] 機械的刺激によるヒト大脳皮質体性感覚野の反応2007

    • Author(s)
      井上健,中西一義,橋詰顕,越智光夫,松本昌泰
    • Organizer
      第37回日本臨床神経生理学会・学術大会
    • Place of Presentation
      宇都宮市
    • Related Report
      2008 Final Research Report
  • [Presentation] 頸椎椎弓形成術後の上肢麻痺に関する前向き研究術中運動誘発電位モニタリングの試み2007

    • Author(s)
      田中信弘,中西一義,佐々木浩文,西田幸司,亀井直輔,當天賢子,濱崎貴彦,山田清貴,伊藤洋平,越智光夫
    • Organizer
      第80回日本整形外科学会学術総会
    • Place of Presentation
      神戸市
    • Related Report
      2008 Final Research Report
  • [Presentation] 脊髄硬膜動静脈瘻に対する運動誘発電位,F波測定による機能評価2007

    • Author(s)
      中西一義,田中信弘,藤本吉範,西川公一郎,奥田晃章,佐々木浩文,西田幸司,亀井直輔,當天賢子,濱崎貴彦,越智光夫
    • Organizer
      第80回日本整形外科学会学術総会
    • Place of Presentation
      神戸市
    • Related Report
      2008 Final Research Report
  • [Presentation] 頸部圧迫性脊髄症における中枢運動伝導時間延長と脊髄誘発電位所見との関連2007

    • Author(s)
      中西一義,田中信弘,亀井直輔,山田清貴,越智光夫
    • Organizer
      第37回日本脊椎脊髄病学会
    • Place of Presentation
      東京都
    • Related Report
      2008 Final Research Report

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Published: 2007-04-01   Modified: 2016-04-21  

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