EIucidation of GaInt3 functions in skeletal development and metabolism
| Project/Area Number |
19791039
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Orthopaedic surgery
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| Research Institution | Nagasaki University |
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Principal Investigator |
YOSHIDA Carolina Andrea Nagasaki University, 大学院・医歯薬学総合研究科, 助教 (50437828)
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| Project Period (FY) |
2007 – 2008
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| Project Status |
Completed (Fiscal Year 2008)
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| Budget Amount *help |
¥3,750,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥450,000)
Fiscal Year 2008: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2007: ¥1,800,000 (Direct Cost: ¥1,800,000)
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| Keywords | 軟代謝学 / Galnt3 / knock out mouse / skeletal develonment / cartilage / bone / skeletal development |
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| Research Abstract |
LNTはムチ型糖する酵素一つでる。
研ではGalnt3子損マス作解しLNT生的能らかにすると目的とし。
Galnt3損マスはリ血症者と似し表現型し野生型マスにして血清中リは濃でFFは減少してい。
らにGalnt3-/-マス大は野生型マス大にべて量共に海綿数が増しているとがか。
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Report
(3 results)
Research Products
(22 results)
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[Journal Article] Runx2 represses myocardin-mediated differentiation and facilitates osteogenic conversion of vascular smooth muscle cells2008
Author(s)
Tanaka T, Sato H, Doi H, Yoshida CA, Shimizu T, Matsui H, Yamazaki M, Akiyama H, Kawai-Kowase K, I so T, Komori T, Arai M, Kurabayashi M
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Journal Title
Mol Cell Biol 28
Pages: 1147-60
Related Report
Peer Reviewed
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[Journal Article] Runx2 determines bone maturity and turnover rate in postnatal bone development and is involved in bone loss in estrogen deficiency2007
Author(s)
Maruyama Z, Yoshida CA, Furuichi T, Amizuka N, Ito M, Fukuyama R, Miyazaki T, Kitaura H, Nakamura K, Fujita T,Kanatani N, Moriishi T, Yamana K, Liu W, Kawaguchi H, Nakamura K, Komori T
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Journal Title
Dev Dyn 236
Pages: 1876-1890
Related Report
Peer Reviewed
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