Development of method for real time visualization of brain derived growth factor and anesthetics

• Project/Area Number: 19791063
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Anesthesiology/Resuscitation studies
• Research Institution: Osaka University
• Principal Investigator: SHIBATA Shocarl Osaka University, 医学系研究科, 寄附講座助教 (70432490)
• Project Period (FY): 2007 – 2008
• Project Status: Completed (Fiscal Year 2008)
• Budget Amount: ¥3,250,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥150,000); Fiscal Year 2008: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2007: ¥2,600,000 (Direct Cost: ¥2,600,000)
• Keywords: 麻酔学 / 一分子 / 脳由来神経成長因子 / 蛍光イメージ法 / 量子ドット

Research Abstract

We developed a method for fusing Qdot-fluorescent probes with brain derived growth factor without destroying the biological binding properties of the growth factor protein. The method can also be applied to other proteins.