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The correlation between DNA polymorphism of Cathecol-O-methyl transferase gene (val 158 met) and postoperative pain

Research Project

Project/Area Number 19791086
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Anesthesiology/Resuscitation studies
Research InstitutionJichi Medical University

Principal Investigator

MOGI Koichi  Jichi Medical University, 医学部, 助教 (80344919)

Project Period (FY) 2007 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥2,670,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2008: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2007: ¥1,500,000 (Direct Cost: ¥1,500,000)
Keywords術後鎮痛 / 遺伝子多型 / 麻酔副作用
Research Abstract

We investigated the correlation between DNA polymorphism of Cathecol-O-methyl transferase gene (val 158 met) and postoperative pain. Our study of 1015 Japanese individuals reports that met/met type was 8.9%, met/val type 40.5 % and val/val type 50.6%. We couldn't find the correlation between DNA polymorphism and postoperative pain.

Report

(4 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • 2007 Annual Research Report
  • Research Products

    (1 results)

All Other

All Presentation (1 results)

  • [Presentation] OPRM1遺伝子A118GとPONVとの関連

    • Author(s)
      茂木康一, 中川雅史, 井上荘一郎, 瀬尾憲正
    • Organizer
      臨床麻酔科学会第30回大会
    • Place of Presentation
      徳島
    • Related Report
      2009 Final Research Report

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Published: 2007-04-01   Modified: 2016-04-21  

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