Adipsin, a new candidate factor in the process of spontaneous abortion, on the effects of complement system and lipid metabolism
| Project/Area Number |
19791176
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Obstetrics and gynecology
|
|---|
| Research Institution | Osaka Prefecture University |
|---|
Principal Investigator |
KUSAKABE Takeshi Osaka Prefecture University, 生命環境科学研究科, 助教 (20319536)
|
|---|
| Project Period (FY) |
2007 – 2009
|
| Project Status |
Completed (Fiscal Year 2009)
|
| Budget Amount *help |
¥3,660,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥660,000)
Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2008: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2007: ¥800,000 (Direct Cost: ¥800,000)
|
|---|
| Keywords | 生殖医学 / 妊娠生理学 / Adipsin / Crry / 巨細胞 / 胎盤 / Adisin / C3 / Factor D / 補体 / 流産 / 栄養膜細胞 / 妊娠 |
|---|
| Research Abstract |
Adipsin, a complemental activator, was detected prominently in the labyrinthine region of abortion placentas. But the complement component 3 and the alternative complement pathway was not markedly activated. Since Crry, an inhibitor for complement acting in the downstream of adipsin, increased, it was suggested that adipsin does not have a strong effect to activate complement system in the abortion placenta. Adipsin may have an influence in the lipid metabolism on the reproductive physiology.
|
Report
(4 results)
Research Products
(17 results)
