Ion transport system in the endolymphatic sac
| Project/Area Number |
19791208
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Otorhinolaryngology
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| Research Institution | Kagawa University |
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Principal Investigator |
MIYASHITA Takenori Kagawa University, 医学部, 助教 (60363214)
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| Project Period (FY) |
2007 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥3,560,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2009: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2008: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2007: ¥2,000,000 (Direct Cost: ¥2,000,000)
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| Keywords | 内耳 / 内リンパ嚢 / イオン輸送 / メニエール病 / イオンチャネル / Na+ / K+-ATPase / イオンイメージング / パッチクランプ / Na^+, K^+-ATPase / パッチグランプ / Na^+, K^+ -ATPase |
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| Research Abstract |
The endolymphatic sac is believed to absorb the endolymph. This study focused on the ion transport control system in the endolymphatic sac. FXYD6 is a control factor of Na pump, and Na pump in the endolymphatic sac may produce Na+ driving force. We confirmed FXYD6 mRNA and protein expression in the endolymphatic sac by RT-PCR and immunohistochemistry. This results suggested that FXYD6 may control the ion transport in the endolymphatic sac.
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Report
(4 results)
Research Products
(58 results)
