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Evaluation of effectiveness of type II thyroplasty for adductor spasmodic dysphonia in animal model

Research Project

Project/Area Number 19791215
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Otorhinolaryngology
Research InstitutionKumamoto University

Principal Investigator

SANUKI Tetuji  Kumamoto University, 大学院・医学薬学研究部, 助教 (10335896)

Project Period (FY) 2007 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥3,690,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2008: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2007: ¥2,000,000 (Direct Cost: ¥2,000,000)
Keywords音声外科 / 喉頭 / 痙攣性発声障害 / 内喉頭筋
Research Abstract

TETSUJI動物モデルを用い痙攣性発声障害に対する甲状軟骨形成術II型の治療効果を評価した。
イヌ摘出喉頭におけるモデルを用いて、最適な吹鳴条件を確定した後に声帯振動と吹鳴音解析した。in Vivoモデルを用い、声帯過内転状態において甲状軟骨を正中切開し、前方開大を行ったところ、振動の回復を認めた例も経験した。このことは痙攣性発声障害における発声障害のメカニズムが声門の過閉鎖であれば、本術式が有効であることの裏付けになると考えられた。

Report

(3 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • Research Products

    (32 results)

All 2009 2008 2007

All Journal Article (14 results) (of which Peer Reviewed: 9 results) Presentation (16 results) Book (2 results)

  • [Journal Article] 披裂軟骨内転術への甲状軟骨形成術I型IV型併用の有用性2008

    • Author(s)
      中村一博、讃岐徹治、一色信彦
    • Journal Title

      日本気管学会食道科会報 59

      Pages: 381-387

    • NAID

      10023918505

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Does Subepithelial Hemorrhage Cause Persistence of Laryngeal Granuloma?2008

    • Author(s)
      Yumoto E、Sanuki T、Miyamaru S、Kumai Y
    • Journal Title

      Laryngoscope 118

      Pages: 932-937

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] 喉頭蓋嚢胞摘出術2008

    • Author(s)
      讃岐徹治
    • Journal Title

      耳鼻咽喉科・頭頸部外科 80

      Pages: 97-102

    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Journal Article] 痙攣性発声障害の外科的治療-喉頭枠組み手術-2008

    • Author(s)
      讃岐徹治
    • Journal Title

      ENTONI 91

      Pages: 64-68

    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Journal Article] 甲状軟骨形成術I型のコツ2008

    • Author(s)
      讃岐徹治
    • Journal Title

      耳鼻臨床 101(9)

      Pages: 722-723

    • NAID

      10021941254

    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Journal Article] Does Subepithelial Hemorrhage Cause Persistence of Laryngeal Granuloma?2008

    • Author(s)
      Yumoto E
    • Journal Title

      Laryngoscope 118

      Pages: 932-937

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 披裂軟骨内転術への甲状軟骨形成術I型IV型併用の有用性2008

    • Author(s)
      中村一博
    • Journal Title

      日本気管学会食道科会報 59

      Pages: 381-387

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 痙攣性発声障害の治療-甲状軟骨形成術II型の立場から-2007

    • Author(s)
      讃岐徹治
    • Journal Title

      JOHNS 23(11)

      Pages: 1713-1716

    • Related Report
      2008 Final Research Report
  • [Journal Article] 性同一性障害と痙攣性発声障害に対する喉頭枠組み手術2007

    • Author(s)
      讃岐徹治、一色信彦、中村一博、湯本英二
    • Journal Title

      喉頭 12(2)

      Pages: 54-58

    • NAID

      10029540466

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Evaluation of Effectiveness of Type II Thyroplasty for Adductor Spasmodic Dysphonia2007

    • Author(s)
      Sanuki T、Isshiki T、 Overall
    • Journal Title

      Laryngoscope 117

      Pages: 2255-2259

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] 不動であった声帯の可動性が披裂軟骨内転術後に回復した2例2007

    • Author(s)
      讃岐徹治、湯本英二
    • Journal Title

      耳鼻と臨床 53

      Pages: 259-262

    • NAID

      130004405088

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Overall Evaluation of Effectiveness of Type II Thyroplasty for Adductor Spasmodic Dysphonia2007

    • Author(s)
      Sanuki T.
    • Journal Title

      Laryngoscope 117

      Pages: 2255-2259

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 性同一性障害と痙攣性発声障害に対する喉頭枠組み手術2007

    • Author(s)
      讃岐徹治
    • Journal Title

      喉頭 12(2)

      Pages: 54-58

    • NAID

      10029540466

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 痙攣性発声障害の治康-甲状軟骨形成術II型の立場から-2007

    • Author(s)
      讃岐徹治
    • Journal Title

      JOHNS 23(11)

      Pages: 1713-1716

    • Related Report
      2007 Annual Research Report
  • [Presentation] 音声障害患者における発声機能検査装置(PA-1000)の検討(第2報)2009

    • Author(s)
      讃岐徹治
    • Organizer
      第21回日本喉頭科学会総会・学術講演会
    • Place of Presentation
      群馬
    • Year and Date
      2009-03-27
    • Related Report
      2008 Annual Research Report
  • [Presentation] 甲状軟骨形成術II型-声門開大調節の工夫-2009

    • Author(s)
      讃岐徹治
    • Organizer
      第24回西日本音声外科研究会
    • Place of Presentation
      山口
    • Year and Date
      2009-01-10
    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Presentation] Effect of type II thyroplasty withtitanium bridges for adductor spasmodic dysphonia2008

    • Author(s)
      Tetsuji Sanuki
    • Organizer
      6th East Asian Conference on Phonosurgery
    • Place of Presentation
      台湾, 高雄
    • Year and Date
      2008-12-05
    • Related Report
      2008 Annual Research Report
  • [Presentation] 甲状腺手術時の神経確認と損傷時の対応2008

    • Author(s)
      讃岐徹治
    • Organizer
      第60回日本気管食道科学会総会・学術講演会
    • Place of Presentation
      熊本
    • Year and Date
      2008-11-06
    • Related Report
      2008 Annual Research Report
  • [Presentation] 甲状軟骨形成術H型前後の音響分析2008

    • Author(s)
      讃岐徹治
    • Organizer
      第53回日本音声言語医学会総会・学術講演会
    • Place of Presentation
      広島
    • Year and Date
      2008-10-23
    • Related Report
      2008 Annual Research Report
  • [Presentation] 内視鏡下両側経鼻腔法により摘出した上咽頭力好ノイドの一症例2008

    • Author(s)
      讃岐徹治
    • Organizer
      第47回日本鼻科学会総会・学術講演会
    • Place of Presentation
      愛知
    • Year and Date
      2008-09-26
    • Related Report
      2008 Annual Research Report
  • [Presentation] 喉頭枠組手術のクリニカルバス運営状況について2008

    • Author(s)
      讃岐徹治
    • Organizer
      第23回クリニカルパス研究会
    • Place of Presentation
      熊本
    • Year and Date
      2008-07-14
    • Related Report
      2008 Annual Research Report
  • [Presentation] Effect of type II thyroplasty with adductor spasmodic dysphonia2008

    • Author(s)
      Tetsuji Sanuki
    • Organizer
      Voice foundation
    • Place of Presentation
      フィラデルフィア
    • Year and Date
      2008-06-01
    • Related Report
      2008 Annual Research Report
  • [Presentation] Office-based steroid injections for vocal fold scarring2008

    • Author(s)
      Tetsuji Sanuki
    • Organizer
      15tth World Congress for Bronchology or 15th World Congress for Bronchoesophagology
    • Place of Presentation
      東京
    • Year and Date
      2008-04-02
    • Related Report
      2008 Annual Research Report
  • [Presentation] Effect of type II thyroplasty with titanium bridges for adductor spasmodic dysphonia2008

    • Author(s)
      讃岐徹治
    • Organizer
      6th East Asian conference on phonosurgery
    • Place of Presentation
      台湾
    • Related Report
      2008 Final Research Report
  • [Presentation] 甲状軟骨形成術II型前後の音響分析2008

    • Author(s)
      讃岐徹治
    • Organizer
      第53回日本音声言語医学会
    • Place of Presentation
      広島
    • Related Report
      2008 Final Research Report
  • [Presentation] Effect of type II thyroplasty with adductor spasmodic dysphonia2008

    • Author(s)
      讃岐徹治
    • Organizer
      37Th Voice foundation
    • Place of Presentation
      フィラデルフィア
    • Related Report
      2008 Final Research Report
  • [Presentation] Effects of type II thyroplasty on acoustic parameters of adductor spasmodic dysphonia2007

    • Author(s)
      讃岐徹治
    • Organizer
      The 9th Japan-Taiwan Conference in Oto-Rhino-Laryngology, Head and Neck Surgery
    • Place of Presentation
      仙台
    • Year and Date
      2007-11-09
    • Related Report
      2008 Final Research Report
  • [Presentation] 痙攣性発声障害に対する外科治療甲状軟骨形成術II型専用手術器具の開発2007

    • Author(s)
      讃岐徹治
    • Organizer
      第52回日本音声言語医学会総会
    • Place of Presentation
      埼玉
    • Year and Date
      2007-10-26
    • Related Report
      2008 Final Research Report
  • [Presentation] Effect of type II thyroplasty with adductor spasmodic dysphonia : Aerodynamic and Videoendoscpic Findings2007

    • Author(s)
      讃岐徹治
    • Organizer
      27th World Congress of the International Associastion of Logopedics and Phoniatrics
    • Place of Presentation
      デンマーク
    • Year and Date
      2007-08-05
    • Related Report
      2008 Final Research Report
  • [Presentation] Effect of type II thyroplasty with adductor spasmodic dysphonia: Aerodynamic and Videoendoscpic Findings2007

    • Author(s)
      Sanuki T
    • Organizer
      27th World Congress of the International Association of Logopedics and Phoniatrics
    • Place of Presentation
      Denmark
    • Year and Date
      2007-08-05
    • Related Report
      2007 Annual Research Report
  • [Book] 声の検査法2009

    • Author(s)
      日本音声言語医学会
    • Total Pages
      280
    • Publisher
      医歯薬出版株式会社新編
    • Related Report
      2008 Final Research Report
  • [Book] 新編声の検査法2009

    • Author(s)
      日本音声言語医学会
    • Total Pages
      280
    • Publisher
      医歯薬出版株式会社
    • Related Report
      2008 Annual Research Report

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Published: 2007-04-01   Modified: 2016-04-21  

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