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The application of stress evaluation and genetic analysis for the tailor-made therapy to the patients in otorhinolaryngolog

Research Project

Project/Area Number 19791233
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Otorhinolaryngology
Research InstitutionKeio University

Principal Investigator

GOTO Fumiyuki  Keio University, 医学部, 講師 (80286567)

Project Period (FY) 2007 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥3,600,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥300,000)
Fiscal Year 2008: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2007: ¥2,300,000 (Direct Cost: ¥2,300,000)
Keywords耳科学 / 耳鼻咽喉科 / 心身症 / ストレス評価 / めまい / 耳鳴 / 心理療法 / 遺伝子多型解析 / ストレス / テーラーメイド医療
Research Abstract

ストレスの客観的評価を耳鼻咽喉科テーラーメイド医療へ応用するために研究を行った。患者の遺伝的な素因がストレスによる患者固有の身体反応を出現させ、個々により治療効果も異なると考えられる。耳鼻咽喉科ストレス疾患患者に対する薬物療法として抗うつ薬を使用し、非薬物治療として認知行動療法、自律訓練法を行いその有用性について検討した。外来患者を対象に耳鼻咽喉科心身症の割合を明らかにした。

Report

(3 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • Research Products

    (35 results)

All 2008 2007

All Journal Article (16 results) (of which Peer Reviewed: 14 results) Presentation (19 results)

  • [Journal Article] 心因性発声障害の治療経験2008

    • Author(s)
      五島史行
    • Journal Title

      日本心療内科学会誌 12

      Pages: 5-9

    • NAID

      10024175290

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] A case of intractable Meniere's disease treated with autogenic training2008

    • Author(s)
      Goto F
    • Journal Title

      BioPsychoSocial Medicine 2

      Pages: 3-3

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] ストレスに関連した聴覚平衡器障害について2008

    • Author(s)
      五島史行、総説
    • Journal Title

      ストレス科学研究 23

      Pages: 15-22

    • Related Report
      2008 Final Research Report
  • [Journal Article] A case of intractable Meniere's disease treated with autogenic trainin2008

    • Author(s)
      Goto F, Nakai K, Kunihiro T,Ogawa K
    • Journal Title

      BioPsychoSocial Medicine

      Pages: 2-3

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] 片頭痛関連のめまい2008

    • Author(s)
      五島史行、矢部はる奈、國弘幸伸、小川郁
    • Journal Title

      Equiribrium Res 67

      Pages: 205-210

    • NAID

      10026087476

    • Related Report
      2008 Annual Research Report 2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] A case of delayed endolymphatic hydrops treated meniette device2008

    • Author(s)
      Goto F, Yabe H, Hayashi K, Kunihiro T, Ogawa K
    • Journal Title

      Equiribrium Res 67

      Pages: 496-499

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] 高齢者メニエール病2008

    • Author(s)
      五島史行、矢部はる奈、國弘幸伸、小川郁
    • Journal Title

      Equiribrium Res 67

      Pages: 500-505

    • Related Report
      2008 Annual Research Report 2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] 、酸化ストレスとメニエール病良性発作性頭位めまい症との関連2008

    • Author(s)
      五島史行、井出里香、矢部はる奈、國弘幸伸、小川郁
    • Journal Title

      Equiribrium Res 68

      Pages: 1-5

    • NAID

      10026087891

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Phobic postural vertigo treated with autogenic training a case report2008

    • Author(s)
      Goto F, Nakai K, Kunihiro T, Ogawa K
    • Journal Title

      Cases Journal 1

      Pages: 189-189

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] A case of intractable Meniere's disease treated with autogenic training2008

    • Author(s)
      Goto F, Nakai K, Kunibiro T, Ogawa K
    • Journal Title

      BioPsychoSocial Medicine

      Pages: 2-3

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A case of delayed endolymphatic hydrops treated2008

    • Author(s)
      Goto F, Yabe H, Hayashi K, Kunihiro T, Ogawa K
    • Journal Title

      meniette device Equiribrium Res 67

      Pages: 496-499

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 酸化ストレスとメニエール病良牲発作性頭位めまい症との関連2008

    • Author(s)
      五島史行、井出里香、矢都はる奈,國弘幸伸、小川郁
    • Journal Title

      Equiribriuni Res 68

      Pages: 1-5

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Phobic postural vertigo treated with autogenic training a case report2008

    • Author(s)
      Goto F, Nakai K, Kunibiro T, Ogawa K
    • Journal Title

      Cases Journal 1

      Pages: 189-189

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 心因性発声障害の治療経験2008

    • Author(s)
      五島 史行
    • Journal Title

      日本心療内科学会誌 12

      Pages: 5-9

    • NAID

      10024175290

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A case of intractable Meniere's disease treated with autogenic training2008

    • Author(s)
      F Goto
    • Journal Title

      BioPsychoSocial Medicine 2

      Pages: 3-3

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 総説 ストレスに関連した聴覚平衡器障害について2008

    • Author(s)
      五島 史行
    • Journal Title

      ストレス科学研究 23

    • Related Report
      2007 Annual Research Report
  • [Presentation] 片頭痛関連めまい2008

    • Author(s)
      五島史行
    • Organizer
      第35回日本頭痛学会
    • Place of Presentation
      東京都市センターホテル
    • Year and Date
      2008-11-10
    • Related Report
      2008 Final Research Report
  • [Presentation] 新しい検査法 ; めまい患者の酸化ストレスレベル評価、メニエール病、良性発作性頭位めまい症との関連2008

    • Author(s)
      五島史行
    • Organizer
      第67回日本めまい平衡医学会
    • Place of Presentation
      秋田
    • Year and Date
      2008-10-31
    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Presentation] The possible contribution of angiitis to the onset of benign paroxysmal positional vertigo (BPPV)2008

    • Author(s)
      五島史行
    • Organizer
      日本耳科学会
    • Place of Presentation
      神戸国際会議場
    • Year and Date
      2008-10-17
    • Related Report
      2008 Final Research Report
  • [Presentation] The possible contribution of angiitis to the onset of benign paroxysmal nositional vertigo (BPPV)2008

    • Author(s)
      五島史行
    • Organizer
      日本耳科学会
    • Place of Presentation
      神戸国際会議場
    • Year and Date
      2008-10-17
    • Related Report
      2008 Annual Research Report
  • [Presentation] 耳鳴りに対する3種類のSSRI(セロトニン再取り込み阻害薬)の治療効果2008

    • Author(s)
      五島史行
    • Organizer
      第53回日本聴覚医学会
    • Place of Presentation
      明治記念館
    • Year and Date
      2008-10-02
    • Related Report
      2008 Final Research Report
  • [Presentation] 耳鳴りに対する3種類のSSRI(セロトニン再取り込み阻害薬)の治療効果2008

    • Author(s)
      五島史行
    • Organizer
      第53回日本聴覚医学会
    • Place of Presentation
      東京明治記念館
    • Year and Date
      2008-10-02
    • Related Report
      2008 Annual Research Report
  • [Presentation] 耳鼻咽喉科におけるSSRI(塩酸パロキセチン、マレイン酸フルボキサミン)の比較2008

    • Author(s)
      五島史行
    • Organizer
      第70回日本耳鼻咽喉科臨床学会
    • Place of Presentation
      長崎ブリックホール
    • Year and Date
      2008-06-28
    • Related Report
      2008 Final Research Report
  • [Presentation] 耳鼻咽喉科におけるSSRI(塩酸パロキセチン、マレイン酸フルホキサミン)の比較2008

    • Author(s)
      五島史行
    • Organizer
      第70回日本耳鼻咽喉科臨床学会
    • Place of Presentation
      長崎ブリックホール
    • Year and Date
      2008-06-28
    • Related Report
      2008 Annual Research Report
  • [Presentation] 耳鼻咽喉科における線維筋痛症の治療2008

    • Author(s)
      五島史行
    • Organizer
      第49回日本心身医学会
    • Place of Presentation
      札幌コンベンションセンター
    • Year and Date
      2008-06-12
    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Presentation] 明らかな器質的異常を認めない発熱患者に対する治療2008

    • Author(s)
      五島史行
    • Organizer
      第109回日本耳鼻咽喉科学会総会・学術講演会
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2008-05-15
    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Presentation] The Characteristics of Patients with Phobic Postural Vertigo Revealed by Psychological Questionnaires2008

    • Author(s)
      Goto F
    • Organizer
      The 25thn Barany society meeting Kyoto
    • Place of Presentation
      Kyoto
    • Year and Date
      2008-04-02
    • Related Report
      2008 Final Research Report
  • [Presentation] The Characteristics of Patients with Phobic Postural Vertigo Revealed by Psychological Questionnaires2008

    • Author(s)
      Goto F
    • Organizer
      The 25th Barany society meeting
    • Place of Presentation
      Kyoto
    • Year and Date
      2008-04-02
    • Related Report
      2008 Annual Research Report
  • [Presentation] Phobic postural vertigo treated with autogenic training a case report2008

    • Author(s)
      Goto F, Nakai K, Kunihiro T, Ogawa K
    • Organizer
      The 25th Barany society meeting Kyoto
    • Place of Presentation
      Kyoto
    • Year and Date
      2008-04-02
    • Related Report
      2008 Annual Research Report
  • [Presentation] 耳鼻咽喉科における心身症の割合と心療耳鼻咽喉科医の必要性2007

    • Author(s)
      五島史行
    • Organizer
      日本心療内科学会
    • Place of Presentation
      大阪国際交流センター
    • Year and Date
      2007-12-02
    • Related Report
      2008 Final Research Report 2007 Annual Research Report
  • [Presentation] 高齢者のメニエール病2007

    • Author(s)
      五島史行
    • Organizer
      第66回日本めまい平衡医学会
    • Place of Presentation
      大阪
    • Year and Date
      2007-11-15
    • Related Report
      2008 Final Research Report
  • [Presentation] 高齢者のメニエール病2007

    • Author(s)
      五島 史行
    • Organizer
      第66回日本めまい平衡医学会
    • Place of Presentation
      大阪国際交流センター
    • Year and Date
      2007-11-15
    • Related Report
      2007 Annual Research Report
  • [Presentation] 片頭痛関連めまい2007

    • Author(s)
      五島 史行
    • Organizer
      第35回日本頭痛学会
    • Place of Presentation
      東京都市センターホテル
    • Year and Date
      2007-11-10
    • Related Report
      2007 Annual Research Report
  • [Presentation] うつ病を含めた耳鼻咽喉科患者に対する塩酸パロキセチンの効果2007

    • Author(s)
      五島史行
    • Organizer
      日本うつ病学会
    • Place of Presentation
      札幌
    • Year and Date
      2007-06-30
    • Related Report
      2008 Final Research Report
  • [Presentation] うつ病を含めた耳鼻咽喉科患者に対する塩酸パロキセチンの効果2007

    • Author(s)
      五島 史行
    • Organizer
      日本うつ病学会
    • Place of Presentation
      札幌コンベンションセンター
    • Year and Date
      2007-06-30
    • Related Report
      2007 Annual Research Report

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Published: 2007-04-01   Modified: 2016-04-21  

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