Collagen production by Muller cell and pathophysiology of idiopathic macular hole formation

• Project/Area Number: 19791298
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Ophthalmology
• Research Institution: Osaka Medical College
• Principal Investigator: SATOU Takaki Osaka Medical College, 医学部, 助教 (20388284)
• Project Period (FY): 2007 – 2009
• Project Status: Completed (Fiscal Year 2009)
• Budget Amount: ¥3,340,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥540,000); Fiscal Year 2009: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000); Fiscal Year 2008: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000); Fiscal Year 2007: ¥1,000,000 (Direct Cost: ¥1,000,000)
• Keywords: ミュラー細胞 / コラーゲン / エストロゲン / キマーゼ / シュラー細胞 / 黄斑円孔

Research Abstract

I examined the influence of estrogen and chymase on collagen production by cultured retinal Muller cells of laboratory rabbits. V type collagen is produced much more than any other type of collagen by the cells when using culture solution including estrogen, chymase and both of them respectively.

Research Products

• [Journal Article] Effect of Hypoxia on Susceptibility of RGC-5 Cell to Nitric Oxide (2010)
  • Author(s): Takaki Sato, Hidehiro Oku, Kazuhiro Tsuruma, Kozo Katsumura, Masamitsu Shimazawa, Hideaki Hara, Tetsuya Sugiyama, Tsunehiko Ikeda
  • Journal Title: Invest. Ophthalmol. Vis. Sci. 51 Pages: 2575-2586
  • Peer Reviewed
• [Journal Article] Effect of Hypoxia on Susceptibility of RGC-5 Cells to Nitric Oxide (2010)
  • Author(s): Takaki Sato, Hidehiro Oku, Kazuhiro Tsuruma, Kozo Katsumura, Masamitsu Shimazawa, Hideaki Hara, Tetsuya Sugiyama, Tsunehiko Ikeda
  • Journal Title: Invest.Ophthalmol.Vis.Sci. 51 Pages: 2575-2586
  • Peer Reviewed
• [Journal Article] 周辺部網膜血管腫に対しPDTを施行したvon Hippel病の1例 (2009)
  • Author(s): 佐藤孝樹、石崎英介、南政宏、植木麻理、池田恒彦、森野以知朗
  • Journal Title: 眼科 51巻 Pages: 1169-1173
  • Peer Reviewed
• [Journal Article] 周辺部網膜血管腫に対しPDTを施行した von Hippel 病の1例 (2009)
  • Author(s): 佐藤孝樹、石崎英介、南政宏、植木麻理、池田恒彦、森野以知朗
  • Journal Title: 眼科 第51巻 Pages: 1169-1173
  • Peer Reviewed
• [Journal Article] 裂孔併発型網膜剥離をきたしたCoats病の1例 (2008)
  • Author(s): 佐藤孝樹, 石崎英介, 南政宏, 前野貴俊, 池田恒彦
  • Journal Title: 臨床眼科 62 Pages: 1907-1910
  • Peer Reviewed
• [Journal Article] 30歳、女性に発症した特発性黄斑円孔 (2008)
  • Author(s): 林田素子, 南政宏, 戸成匡宏, 福本雅格, 佐藤孝樹, 石崎英介, 前野貴俊, 池田恒彦
  • Journal Title: 眼科手術 21 Pages: 382-384
  • NAID: 10024370631
  • Peer Reviewed
• [Journal Article] SENIOR-ROKEN SYNDROME COMPLICATED WITH SEVER COATS DISEASE-KILE EXUDATIVE RETINOPATHY (2007)
  • Author(s): Takaki Sato, Masashi Mimura, Tetsuya Sugiyama Takatoshi Maeno, Eisuke Ishizaki, Masahiro Minami, Jun Sugasawa, Tsunehiko Ikeda
  • Journal Title: RETINAL CASES & BRIEF REPORTS 1 Pages: 172-174
  • Peer Reviewed
• [Presentation] レーザースペックルによる網脈絡膜循環測定を施行した中心性漿液性脈絡網膜症の1例 (2009)
  • Author(s): 佐藤孝樹, 中泉敦子, 福本雅格, 石崎英介, 南政宏, 植木麻理, 池田恒彦
  • Organizer: 第26回日本眼循環学会
  • Place of Presentation: 名古屋
  • Year and Date: 2009-12-05
• [Presentation] レーザースペックルによる網脈絡膜循環測定を施行した中心性漿液性脈絡網膜症の1例 (2009)
  • Author(s): 佐藤孝樹, 中泉敦子, 福本雅格, 石崎英介, 南政宏, 植木麻理, 池田恒彦
  • Organizer: 第26回日本眼循環学会
  • Place of Presentation: 名古屋国際会議場(愛知)
  • Year and Date: 2009-12-05
• [Presentation] 周辺部網膜血管腫に対しPDTを施行したvon Hippel病の1例 (2008)
  • Author(s): 佐藤孝樹, 藤本陽子, 石崎英介, 南政宏, 植木麻理, 池田恒彦, 森野以知朗
  • Organizer: 第61回臨床眼科学会
  • Place of Presentation: 京都