Comprehensive clinical study of oral management for hematopoietic stem cell transplantation

• Project/Area Number: 19791486
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Surgical dentistry
• Research Institution: University of Tsukuba
• Principal Investigator: YAMAGATA Kenji University of Tsukuba, 大学院・人間総合科学研究科, 講師 (00420084)
• Project Period (FY): 2007 – 2009
• Project Status: Completed (Fiscal Year 2009)
• Budget Amount: ¥3,780,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥480,000); Fiscal Year 2009: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2008: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2007: ¥1,700,000 (Direct Cost: ¥1,700,000)
• Keywords: 口腔管理 / 小児 / 成人 / 歯科管理プロトコール / 造血幹細胞移植 / 埋伏智歯

Research Abstract

The hematopoietic stem cell transplantation (HSCT) is performed for hematopoietic disease. Pre-HSCT dental treatments and oral care are anticipated to decrease the risk of local and systemic infections during immunosuppression. In the present study, pre-HSCT dental management protocol was established and systemic infection from odontogenic infection was not shown in all cases. Moreover, oral care for decreasing oral mucositis was approved effective method.

Research Products

• [Journal Article] Prospective study establishing a management plan for impacted third molar in patients undergoing hematopoietic stem cell transplantation (2011)
  • Author(s): Yamagata K, et al.
  • Journal Title: Oral Surg Oral Med Oral Pathol Oral Radiol Endod Volume: 111 Pages: 146-52
  • NAID: 120007137588
  • Peer Reviewed
• [Journal Article] 顎口腔領域に生じた節外性悪性リンパ腫の6例 (2008)
  • Author(s): 山縣憲司、鬼澤浩司郎、吉田廣
  • Journal Title: 日口診誌 21巻 Pages: 273-277
  • NAID: 10025567340
  • Peer Reviewed
• [Journal Article] 顎口腔領域に生じた節外性悪性リンパ腫の6例 (2008)
  • Author(s): 山縣憲司、鬼澤浩司郎、吉田廣
  • Journal Title: 日口診誌 21 Pages: 273-277
  • NAID: 10025567340
  • Peer Reviewed
• [Presentation] 造血幹細胞移植患者に対する口腔管理の有効性 (2010)
  • Author(s): 大森翔英、山縣憲司, 他
  • Organizer: 第18回茨城県歯科医学会
  • Place of Presentation: 水戸プラザホテル
  • Year and Date: 2010-02-28
• [Presentation] 造血幹細胞移植患者に対する口腔管理の有効性 (2010)
  • Author(s): 大森翔英、山縣憲司, 他
  • Organizer: 第18回 茨城県歯科医学会
  • Place of Presentation: 水戸プラザホテル
  • Year and Date: 2010-02-28
• [Presentation] Dental management plan before hematopoietic stem cell transplantation (2009)
  • Author(s): Kenji Yamagata, et al.
  • Organizer: 14 th Congress of the asia-pacific blood and marrow transplantation
  • Place of Presentation: Grand Hilton Seoul, Korea
• [Presentation] 造血幹細胞移植前歯科管理における埋伏智歯の管理基準についての検討 (2009)
  • Author(s): 山縣憲司, 他
  • Organizer: 第63回NPO法人日本口腔科学会学術集会
  • Place of Presentation: アクトシティ浜松
• [Presentation] 造血幹細胞移植前歯科管理における埋伏智歯の管理基準についての検討 (2009)
  • Author(s): 山縣憲司, 他
  • Organizer: 第63回 NPO法人 日本口腔科学会学術集会
  • Place of Presentation: アクトシティ浜松
• [Presentation] Dental management plan before hematopoietic stem cell transplantation (2009)
  • Author(s): 山縣憲司, et al.
  • Organizer: 14th Congress of the asia-pacific blood and marrow transplantation
  • Place of Presentation: Grand Hilton Seoul, Korea
• [Book] Dental management before hematopoietic stem cell transplantation for adult and pediatric patients with hematologic disease. In Hematopoietic stem cell transplantation research advances (Edit. Karl B. Neumann) (2008)
  • Author(s): Kenji Yamagata, Kojiro Onizawa, Hiroshi Yoshida
  • Publisher: Nova Science Publishers
• [Book] Dental management before hematopoietic stem cell transplantation for adult and pediatric patients with hematologic disease. In Hematopoietic stem cell transplantation research advances(Edit. Karl B. Neumann) (2008)
  • Author(s): Kenji Yamagata, Kojiro Onizawa, Hiroshi Yoshida
  • Total Pages: 248
  • Publisher: Nova Science Publishers