Expression analysis of CENP-H gene in human salivary gland carcinomas

• Project/Area Number: 19791519
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Surgical dentistry
• Research Institution: Hiroshima University
• Principal Investigator: SHIGEISHI Hideo Hiroshima University, 大学院・医歯薬学総合研究科, 助教 (90397943)
• Project Period (FY): 2007 – 2008
• Project Status: Completed (Fiscal Year 2008)
• Budget Amount: ¥2,870,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥270,000); Fiscal Year 2008: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000); Fiscal Year 2007: ¥1,700,000 (Direct Cost: ¥1,700,000)
• Keywords: 細胞周期 / 悪性腫瘍 / セントロメア蛋白質

Research Abstract

CENP-Hの発現と臨床病理学的指標や転移および予後との関わりについて検討した.その結果,CENP-Hの過剰発現と腫瘍の増殖活性との間の相関関係を認め,CENP-Hの過剰な発現が,悪性転化にも関わっている可能性が強く示唆された.

Research Products

• [Journal Article] Expression of TPX2 in salivary gland carcinomas (2009)
  • Author(s): Shigeishi H, Ohta K, Hiraoka M, Fujimoto S, Minami M, Higashikawa K, Kamata N.
  • Journal Title: Oncol Rep 21(2) Pages: 341-344
  • Peer Reviewed
• [Journal Article] Expression of TPX2 in salivary gland carcinomas (2009)
  • Author(s): Shigeishi H
  • Journal Title: Oncology Reports 21 Pages: 341-344
  • Peer Reviewed
• [Journal Article] Masayuki Taki and Nobuyuki Kamata. Increased expression of CENP-Hgene in human salivarygland carcinomas (2008)
  • Author(s): Hideo Shigeishi, Yoshitsugu Mitani, ShigehiroOno, Kouji Ohta, Koichiro Higashikawa,
  • Journal Title: Oral Sience International Vol.5 Pages: 43-51
  • Peer Reviewed
• [Journal Article] Expression of epiregulin, a novel epidermal growth factor ligand associated with prognosis in human oral squamous cell carcinomas (2008)
  • Author(s): Shigeishi H, Higashikawa K, Hiraoka M, Fujimoto S, Mitani Y, Ohta K, Takechi M, Kamata N.
  • Journal Title: Oncol Rep 19(6) Pages: 1557-1564
  • Peer Reviewed
• [Journal Article] Expression of epiregulin, a novel epidermal growth factor ligand associated with prognosis in human oral squamous cell carcinomas (2008)
  • Author(s): Shigeishi H
  • Journal Title: Oncology Reports 19 Pages: 1557-1564
  • Peer Reviewed
• [Journal Article] Increased expression of CENP-H fene in human salivary gland carcinomas. (2008)
  • Author(s): Shigeishi H
  • Journal Title: Oral Sience International 5(掲載決定)
  • Peer Reviewed
• [Presentation] 口腔扁平上皮癌におけるRHAMM遺伝子の発現解析 (2008)
  • Author(s): 重石英生
  • Organizer: 日本口腔外科学会総会
  • Place of Presentation: 徳島