Periodontal regeneration following BMP-root conditioning and collagen scaffold implantation.
Project/Area Number |
19791606
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Single-year Grants |
Research Field |
Periodontal dentistry
|
Research Institution | Hokkaido University |
Principal Investigator |
MIYAJI Hirofumi Hokkaido University, 北海道大学病院, 講師 (50372256)
|
Project Period (FY) |
2007 – 2009
|
Project Status |
Completed (Fiscal Year 2009)
|
Budget Amount *help |
¥3,640,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥540,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2008: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2007: ¥1,300,000 (Direct Cost: ¥1,300,000)
|
Keywords | 歯周組織再生 / BMP-2 / コラーゲン / スキャフォールド / 再生医学 / BMP / 歯槽骨 / セメント質 / 骨増生 / 生体親和性 |
Research Abstract |
We examined whether combined therapy of BMP-conditioning and implantation of a collagen scaffold stimulated periodontal regeneration. The collagen scaffold was composed of collagen hydrogel and type I collagen sponge. Application of collagen scaffold promoted bone augmentation and periodontal regeneration with high biocompatibility and tissue replacing ability. Root surface conditioning with BMP and implantation of collagen scaffold sufficiently enhanced periodontal regeneration and rarely induced ankylosis. The combined therapy is expected to be a suitable therapy for periodontal tissue engineering.
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Report
(4 results)
Research Products
(26 results)