| Budget Amount *help |
¥3,320,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥420,000)
Fiscal Year 2009: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2008: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2007: ¥1,500,000 (Direct Cost: ¥1,500,000)
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| Research Abstract |
We studied the possibility of tissue regeneration using human umbilical cord derived cells. Frow cytometry revealed the prospective evaluation that is most of the cells were CD44 positive, CD34 negative, wherese most cells were STRO-1 negative.
Following AA, β-GP and Dex treatment, cells failed to fuse and transdifferantiated along an osteogenic pathway expressing OC, BSP and COL I.These results show that human umbilical cord derived cells pluripotent stem cells capable of differentiation along osteogenic lineages.
Human umbilical cord derived cells may be have a possibility for the development of new tissue regeneration therapies.
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