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The effect of Er : YAG laser on periodontal ligament cell in vitroand in vivo studies

Research Project

Project/Area Number 19890079
Research Category

Grant-in-Aid for Young Scientists (Start-up)

Allocation TypeSingle-year Grants
Research Field Periodontal dentistry
Research InstitutionTokyo Medical and Dental University

Principal Investigator

MIZUTANI Koji  Tokyo Medical and Dental University, 歯学部附属病院, 医員 (60451910)

Project Period (FY) 2007 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥3,085,000 (Direct Cost: ¥2,680,000、Indirect Cost: ¥405,000)
Fiscal Year 2008: ¥1,755,000 (Direct Cost: ¥1,350,000、Indirect Cost: ¥405,000)
Fiscal Year 2007: ¥1,330,000 (Direct Cost: ¥1,330,000)
Keywords歯周組織 / レーザー / 生体刺激効果 / 歯根膜
Research Abstract

エルビウム・ヤグ(Er : YAG)レーザーを骨芽細胞に照射することにより、形態の著しい変化を伴わず、増殖が促進される傾向が示された。歯根膜細胞はheterogenousであり、骨芽細胞様の細胞も含んでいるため、これまでの骨芽細胞への様々な低出力レーザー照射の効果と同様に、歯根膜細胞の石灰化が促進されることが推測された。
また、従来用いられていなかった高パルスによる照射の効果の検証において、イヌを用いた実験により安全性が確認された。

Report

(3 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • Research Products

    (14 results)

All 2009 2008 2007

All Journal Article (9 results) (of which Peer Reviewed: 8 results) Presentation (5 results)

  • [Journal Article] Long-term histological analysis of bone tissue alteration and healing following Er : YAG laser irradiation in comparison with electrosurgery2009

    • Author(s)
      Yoshino T, Aoki A, Oda S, Takasaki A A, Mizutani K, Sasaki K M, Kinoshita A, Watanabe H, Ishikawa I, Izumi Y
    • Journal Title

      Journal of Periodontology 80

      Pages: 82-92

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Application of lasers in periodontics-Is it truly innovative or mythic?-2009

    • Author(s)
      Ishikawa I, Aoki A, Takasaki A A, Mizutani K, Sasaki K M, Izumi Y
    • Journal Title

      Periodontology2000 50

      Pages: 90-126

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Application of lasers in periodontics : true innovation or myth?2009

    • Author(s)
      Ishikawa, et al.
    • Journal Title

      Periodontology 2000 50

      Pages: 90-126

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Long-Term Histologic Analysis of Bone Tissue Alteration and HealingFollowing Er : YAG Laser Irradiation Compared to Electrosurgery2009

    • Author(s)
      Yoshino, et al.
    • Journal Title

      Journal of Periodontology 80

      Pages: 82-92

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Photo-bio-modulation Laser Strategies in Periodontal Therapy2008

    • Author(s)
      Takasaki A A, Aoki A, Mizutani K, Pourzarandian A, Ruwanpura S M, Iwasaki K, Noguchi K, Oda S, Watanabe H, Ishikawa I, Izumi Y
    • Journal Title

      Proceedings of Light-Activated Tissue Regeneration and Therapy Conference. Springer

      Pages: 181-190

    • Related Report
      2008 Final Research Report
  • [Journal Article] Current status of clinical laser applications in periodontal therapy2008

    • Author(s)
      Aoki A, Mizutani K, Takasaki A A, Sasaki K M, Nagai S, Schwarz F, Yoshida I, Eguro T, Zeredo J L, Izumi Y
    • Journal Title

      General Dentistry 56(7)

      Pages: 674-687

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Current status of clinical laser applications in periodontal therapy2008

    • Author(s)
      Aoki, Mizutani, Takasaki etal.
    • Journal Title

      General Dentistry 56

      Pages: 674-687

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 歯周治療におけるレーザーの応用2007

    • Author(s)
      青木章、水谷幸嗣、永井茂之, 他
    • Journal Title

      日本歯科先端技術研究所学術会誌 13

      Pages: 127-136

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] ErYAG therapy for peri-implant infection: A Histological study2007

    • Author(s)
      Takasaki AA, Aoki A, Mizutani K. 他
    • Journal Title

      Laser in Medical Science 22

      Pages: 143-157

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Presentation] リン酸カルシウム骨セメントを応用した歯槽堤増大術の組織学的評価-イヌ骨欠損モデル-2009

    • Author(s)
      佐藤郁文, 秋月達也, 小田茂, 土岡弘明, 林千絵, 高崎アリステオ淳志, 水谷幸嗣, 川勝紀子, 木下淳博, 石川烈, 和泉雄一
    • Organizer
      第8回日本再生医療学会総会
    • Place of Presentation
      東京
    • Year and Date
      2009-03-05
    • Related Report
      2008 Final Research Report
  • [Presentation] チゼル型チップを用いた高パルスEr : YAGレーザー照射による歯石除去効果2008

    • Author(s)
      水谷幸嗣、青木章、高崎アリステオ淳志、丸山裕昭、和泉雄一
    • Organizer
      日本歯科保存学会第128回春季学術大会
    • Place of Presentation
      新潟
    • Year and Date
      2008-06-06
    • Related Report
      2008 Final Research Report
  • [Presentation] チゼル型チップを用いた高パルスEr : YAGレーザー照射による効果2008

    • Author(s)
      水谷幸嗣, 青木章, 高崎アリステオ淳志, 丸山裕昭, 和泉雄一
    • Organizer
      日本歯科保存学会第128回春季学術大会
    • Place of Presentation
      新潟
    • Year and Date
      2008-06-06
    • Related Report
      2008 Annual Research Report
  • [Presentation] Effect of high pulse rate Er : YAG laser irradiation using a chisel tip on subgingival calculus removal in vitro2008

    • Author(s)
      Mizutani K, Aoki A, Takasaki A A, Maruyama H, Schwarz F, Yamada T, Ichinose S, Ishikawa I, Izumi Y
    • Organizer
      11th Meeting of the World Federationfor Laser Dentistry
    • Place of Presentation
      Hong Kong
    • Related Report
      2008 Final Research Report
  • [Presentation] フラップ手術における高パルスEr:YAGレーザーの応用の臨床的評価2007

    • Author(s)
      青木章、水谷幸嗣, 他
    • Organizer
      第50回秋季日本歯周病学会
    • Place of Presentation
      東京
    • Year and Date
      2007-09-21
    • Related Report
      2007 Annual Research Report

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Published: 2007-04-01   Modified: 2016-04-21  

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