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The role of the estrogen receptor on salivary gland tumors

Research Project

Project/Area Number 19890146
Research Category

Grant-in-Aid for Young Scientists (Start-up)

Allocation TypeSingle-year Grants
Research Field Surgical dentistry
Research InstitutionEhime University

Principal Investigator

YOSHIMURA Tomohide  Ehime University, 医学部・附属病院, 医員 (80452697)

Project Period (FY) 2007 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥3,075,000 (Direct Cost: ¥2,670,000、Indirect Cost: ¥405,000)
Fiscal Year 2008: ¥1,755,000 (Direct Cost: ¥1,350,000、Indirect Cost: ¥405,000)
Fiscal Year 2007: ¥1,320,000 (Direct Cost: ¥1,320,000)
Keywords唾液腺癌 / エストロゲン / エストロゲンレセプター / タモキシフェン / ホルモン療法
Research Abstract

エストロゲンレセプター発現唾液腺癌由来細胞株は、エストロゲン処理により細胞増殖が亢進することが明らかとなった。そのため、エストロゲンレセプターの拮抗剤であるタモキシフェンにより、細胞増殖の抑制が期待される。また、耳下腺、顎下腺、舌下腺および口唇線、舌腺、口蓋腺といった小唾液腺の正常唾液腺組織および腺様嚢胞癌、粘表皮癌などの唾液腺癌組織のエストロゲンレセプター発現頻度は多くないと考えられた。

Report

(3 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • Research Products

    (2 results)

All 2008

All Presentation (2 results)

  • [Presentation] Functional restration with dental implant after the treatment of oral cancer2008

    • Author(s)
      Tomohide Yoshimura, Tomoki Sumida, Ryuichi Murase, Koh-ich Nakashiro, Hiroyuki Hamakawa
    • Organizer
      12th International Congress on Oral Cancer
    • Place of Presentation
      shanghai
    • Related Report
      2008 Final Research Report
  • [Presentation] Functional restration with dental implant after the treatment of oral cancer.2008

    • Author(s)
      Tomohide Yoshimura, Tomoki Sumida, Ryuichi Murase, Koh-ich Nakashiro, Hiroyuki Hamakawa
    • Organizer
      12th International Congress on Oral Cancer
    • Place of Presentation
      shanghai, china
    • Related Report
      2008 Annual Research Report

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Published: 2007-04-01   Modified: 2016-04-21  

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