Development of Fluorescence Probe for Selective Detection of Glutamate

• Project/Area Number: 19890252
• Research Category: Grant-in-Aid for Young Scientists (Start-up)
• Allocation Type: Single-year Grants
• Research Field: Physical pharmacy
• Research Institution: Hyogo University of Health Sciences
• Principal Investigator: TSUKAMOTO Koji Hyogo University of Health Sciences, 薬学部, 助教 (00454794)
• Project Period (FY): 2007 – 2008
• Project Status: Completed (Fiscal Year 2008)
• Budget Amount: ¥3,075,000 (Direct Cost: ¥2,670,000、Indirect Cost: ¥405,000); Fiscal Year 2008: ¥1,755,000 (Direct Cost: ¥1,350,000、Indirect Cost: ¥405,000); Fiscal Year 2007: ¥1,320,000 (Direct Cost: ¥1,320,000)
• Keywords: 分析化学 / 可視化 / 分子認識

Research Abstract

生体内で神経伝達物質等の重要な役割を担うグルタミン酸を高感度に検出するため、グルタミン酸が存在すると蛍光を発する「グルタミン酸蛍光プローブ」を開発した。