| Project/Area Number |
19F19089
|
|---|
| Research Category |
Grant-in-Aid for JSPS Fellows
|
| Allocation Type | Single-year Grants |
|---|
| Section | 外国 |
|---|
| Review Section |
Basic Section 45020:Evolutionary biology-related
|
|---|
| Research Institution | The University of Tokyo |
|---|
Principal Investigator |
岩崎 渉 東京大学, 大学院理学系研究科(理学部), 准教授 (50545019)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
CHEN ERIC 東京大学, 大学院理学系研究科, 外国人特別研究員
|
|---|
| Project Period (FY) |
2019-04-25 – 2021-03-31
|
| Project Status |
Completed (Fiscal Year 2020)
|
| Budget Amount *help |
¥2,300,000 (Direct Cost: ¥2,300,000)
Fiscal Year 2020: ¥1,100,000 (Direct Cost: ¥1,100,000)
Fiscal Year 2019: ¥1,200,000 (Direct Cost: ¥1,200,000)
|
|---|
| Keywords | ゲノム進化 / バイオインフォマティクス / genome / evolution |
|---|
| Outline of Research at the Start |
In this study, we will test the controversial hypothesis that polyploids are better at adapting to new niches compared to their diploid counterparts and if recent hybrids are more advantageous than diploids and explore if this phenomenon can be explained by genomic data. Specifically, we will use a recent novel design that used to study the evolution of antibiotic resistance, to measure the adaptation speed of these model fungi.
|
| Outline of Annual Research Achievements |
In the second year, we successfully conducted experiments with gradients of increasing harshness with two different kinds of stress, such as fungicide and high salt concentration. As expected, each successive zone required a different mechanism for the fungi to cope with the new environment. The speed of adaptation in this variant became a proxy of how fast the fungi can reorient themselves to new stress with each new zone. We also conducted mixing competition assay into additional culture experiments by making the starting colony a 50:50 mixture of hybrid-diploid pair that share closely related subgenomes. Nanopore sequencing was also conducted to retrieve genomic data. The results are being analyzed in depth.
|
| Research Progress Status |
令和2年度が最終年度であるため、記入しない。
|
| Strategy for Future Research Activity |
令和2年度が最終年度であるため、記入しない。
|
