On the Role of Mechanical Interactions in Cellular Systems
| Project/Area Number |
19F19705
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| Research Category |
Grant-in-Aid for JSPS Fellows
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| Allocation Type | Single-year Grants |
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| Section | 外国 |
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| Review Section |
Basic Section 13040:Biophysics, chemical physics and soft matter physics-related
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| Research Institution | Okinawa Institute of Science and Technology Graduate University |
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Principal Investigator |
フリード エリオット 沖縄科学技術大学院大学, 力学と材料科学ユニット, 教授 (70735761)
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| Co-Investigator(Kenkyū-buntansha) |
KWIECINSKI JAMES 沖縄科学技術大学院大学, 数理力学と材料科学ユニット, 外国人特別研究員
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| Project Period (FY) |
2019-10-11 – 2022-03-31
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| Project Status |
Completed (Fiscal Year 2021)
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| Budget Amount *help |
¥1,400,000 (Direct Cost: ¥1,400,000)
Fiscal Year 2021: ¥300,000 (Direct Cost: ¥300,000)
Fiscal Year 2020: ¥700,000 (Direct Cost: ¥700,000)
Fiscal Year 2019: ¥400,000 (Direct Cost: ¥400,000)
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| Keywords | Mathematical model / cellular systems / protein interaction / immune system / macromolecules / B-cell |
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| Outline of Research at the Start |
The goal of this research is to build a realistic mathematical model of membrane-mediated interactions between proteins and macromolecules, focusing on how they affect the shape of lipid bilayers and on the prelude to antigen extraction by white-blood cells. The research will increase the understanding of key cellular processes. By determining the basic interaction laws between proteins and macromolecules and the process by which they assemble and aggregate, the computational cost of large-scale simulations will be significantly reduced, leading to the ability to model more complex systems.
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| Outline of Annual Research Achievements |
Dr. Kwiecinski was preparing a sole author paper on a mathematical model describing the relaxation of rotational behavior of viscoelastic solids entitled "Relaxation of Viscoelastic Tumblers with Application to 1I/2017 (`Oumuamua) and 4179 Toutatis" with plans to submit this to the Monthly Notices for the Royal Astronomical Society.
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| Research Progress Status |
令和3年度が最終年度であるため、記入しない。
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| Strategy for Future Research Activity |
令和3年度が最終年度であるため、記入しない。
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Report
(3 results)
Research Products
(2 results)
