| Budget Amount *help |
¥45,890,000 (Direct Cost: ¥35,300,000、Indirect Cost: ¥10,590,000)
Fiscal Year 2022: ¥8,450,000 (Direct Cost: ¥6,500,000、Indirect Cost: ¥1,950,000)
Fiscal Year 2021: ¥8,450,000 (Direct Cost: ¥6,500,000、Indirect Cost: ¥1,950,000)
Fiscal Year 2020: ¥8,450,000 (Direct Cost: ¥6,500,000、Indirect Cost: ¥1,950,000)
Fiscal Year 2019: ¥20,540,000 (Direct Cost: ¥15,800,000、Indirect Cost: ¥4,740,000)
|
|---|
| Outline of Final Research Achievements |
By utilizing metallic lithium, we have established 1) a method for inserting various atoms, including boron and silicon, into the carbon-nitrogen bond in the indole ring and 2) a simple and convenient method for the synthesis of substituted heteroles such as siloles and phospholes via the corresponding dilithium reagents that are reductively generated from thiophenes.
We have established a method to construct carbazole and seven-membered dibenzoazepine skeletons by the reactions of dibenzothiophene dioxide with alkanamine and N-benzylbenzaldehyde imine, respectively, under basic conditions. Furthermore, the synthesis of a series of heteroatom-containing helicenes by utilizing aromatic ring metamorphosis has been established, which have clarified the usefulness of aromatic ring metamorphosis.
|
