| Project/Area Number |
19H01012
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (A)
|
| Allocation Type | Single-year Grants |
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| Section | 一般 |
|---|
| Review Section |
Medium-sized Section 46:Neuroscience and related fields
|
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| Research Institution | Institute of Physical and Chemical Research |
|---|
Principal Investigator |
McHugh Thomas 国立研究開発法人理化学研究所, 脳神経科学研究センター, チームリーダー (50553731)
|
|---|
| Project Period (FY) |
2019-04-01 – 2020-03-31
|
| Project Status |
Discontinued (Fiscal Year 2019)
|
| Budget Amount *help |
¥33,540,000 (Direct Cost: ¥25,800,000、Indirect Cost: ¥7,740,000)
Fiscal Year 2019: ¥14,690,000 (Direct Cost: ¥11,300,000、Indirect Cost: ¥3,390,000)
|
|---|
| Keywords | hippocampus / memory / cortex / engram / physiology / Memory / ripples / consolidation |
|---|
| Outline of Research at the Start |
In this project we will combine physiology and genetic approaches to investigate the mechanisms of integration of information and oscillations, revealing their individual roles in memory, as well as yield insight to treatments of disorders involving aberrant neural dynamics.
|
| Outline of Annual Research Achievements |
This grant was only active for 3 months due to the awarding of a KIBAN S on the same research topic in 07/2019. During that period I actively prepared for experiments examining the physiology of cFos positive neurons in regions upstream and downstream of CA1, CA3 and the mPFC (ACC). We bred the necessary mice for the experiments and prepared the required viral and physiological reagents. Pilot injects were conducted to control the timeline of viral expression and ensure both regions can be targeted.
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| Research Progress Status |
令和元年度が最終年度であるため、記入しない。
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| Strategy for Future Research Activity |
令和元年度が最終年度であるため、記入しない。
|
