| Budget Amount *help |
¥17,160,000 (Direct Cost: ¥13,200,000、Indirect Cost: ¥3,960,000)
Fiscal Year 2022: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2021: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2020: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2019: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
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| Outline of Final Research Achievements |
The crucial role of novel gene transcription within brain neurons during the memory formation is well established. Transcription factors, which are vital components that directly modulate gene expression, are known to orchestrate the plastic change of the nervous system via the dynamic influence to the transcriptome. Despite their importance, there are lack of understanding regarding the dynamic activity patterns of transcription factors within a live brain during the memory formation process. The current study had harnessed a cutting edge technology to elucidate the temporal dynamics of activity across a multitude of transcription factors in mice brain. Consequently, the study had revealed the pivotal role these transcription factors play in the regulation of time-course of memory formation.
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