| Budget Amount *help |
¥17,290,000 (Direct Cost: ¥13,300,000、Indirect Cost: ¥3,990,000)
Fiscal Year 2021: ¥5,850,000 (Direct Cost: ¥4,500,000、Indirect Cost: ¥1,350,000)
Fiscal Year 2020: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2019: ¥5,980,000 (Direct Cost: ¥4,600,000、Indirect Cost: ¥1,380,000)
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| Outline of Final Research Achievements |
The purpose of this research was to establish an original organ-scale multicolor 3D staining and observation technique. During the research, we invented a new, high-performance tissue 3D staining protocol named CUBIC-HistoVIsion (CUBIC-HV) based on our finding that the biological tissue can be defined as a kind of gel. The published paper gathered worldwide attention and was selected as one of the 2020 Top 50 Life and Biological Sciences Articles in the journal. We also conducted many collaboration research by using the newly developed technology.
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