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Elucidation of the mechanism of eye deformation caused by pathological myopia and establishment of eye wall regeneration therapy

Research Project

Project/Area Number 19H03808
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Review Section Basic Section 56060:Ophthalmology-related
Research InstitutionTokyo Medical and Dental University

Principal Investigator

Ohno-Matsui Kyoko  東京医科歯科大学, 大学院医歯学総合研究科, 教授 (30262174)

Co-Investigator(Kenkyū-buntansha) 鴨居 功樹  東京医科歯科大学, 大学院医歯学総合研究科, 講師 (40451942)
田中 敏博  東京医科歯科大学, 統合研究機構, 教授 (50292850)
Project Period (FY) 2019-04-01 – 2022-03-31
Project Status Completed (Fiscal Year 2022)
Budget Amount *help
¥15,470,000 (Direct Cost: ¥11,900,000、Indirect Cost: ¥3,570,000)
Fiscal Year 2021: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2020: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2019: ¥6,240,000 (Direct Cost: ¥4,800,000、Indirect Cost: ¥1,440,000)
Keywords近視 / 強膜 / 眼球形状 / 病的近視 / 後部ぶどう腫 / 光干渉断層計 / 遺伝子解析 / 実験近視 / 超広角OCT
Outline of Research at the Start

病的近視による失明を防ぐためには、合併病変の発生前に後部ぶどう腫を抑制する必要がある。申請者は、超広角光干渉断層計(OCT)を用いて、世界で初めて後部ぶどう腫の全体像の
可視化に成功した。そこで、1)超広角OCTを用いて後部ぶどう腫を客観的・定
量的に評価する自動システムを構築、2)近視の度数ではなく、後部ぶどう腫の原因遺伝子を解明、3)後部ぶどう腫の動物モデルを確立し、4)眼球壁構成組織の再生治療により、ぶどう腫発生が抑制できるか、を調べる。本研究の成果により、後部ぶどう腫の早期診断から予防治療に至るまで、病的近視による失明を抑止する根本治療の確立が期待できる。

Outline of Final Research Achievements

Using ultra-wide angle OCT and 3D MRI, long-term observation of cases in various age groups from childhood to middle age and beyond was conducted to analyze ocular shape abnormalities. The results showed that scleral shape abnormalities had already begun in childhood on the nasal side of the optic nerve papilla, indicating that eye shape abnormalities in pathological myopia had already occurred in childhood. In middle-aged and older adults, the choroid and sclera become thinner and thinner, and as a result, the location of the eye shape abnormality differs from that in childhood, and the shape abnormality also progresses over time. To control the shape abnormality, we developed a prototype photocrosslinking therapy probe for the posterior sclera and confirmed scleral sclerosis in a rabbit model.

Academic Significance and Societal Importance of the Research Achievements

今回の研究成果により、小児期にすでに中高年以降に高度の眼球形状異常にいたる症例を同定することができることが示された。そのことにより、通常の学童近視と、失明に至る病的近視を若い時期に区別することが可能となり、失明予防に極めて重要な成果と考えらえる。

Report

(4 results)
  • 2022 Final Research Report ( PDF )
  • 2021 Annual Research Report
  • 2020 Annual Research Report
  • 2019 Annual Research Report
  • Research Products

    (45 results)

All 2023 2022 2021 2020 2019 2018

All Journal Article (27 results) (of which Int'l Joint Research: 14 results,  Peer Reviewed: 27 results,  Open Access: 9 results) Presentation (15 results) (of which Int'l Joint Research: 13 results,  Invited: 15 results) Book (3 results)

  • [Journal Article] IMI?Management and Investigation of High Myopia in Infants and Young Children2023

    • Author(s)
      Flitcroft Ian、Ainsworth John、Chia Audrey、Cotter Susan、Harb Elise、Jin Zi-Bing、Klaver Caroline C. W.、Moore Anthony T.、Nischal Ken K.、Ohno-Matsui Kyoko、Paysse Evelyn A.、Repka Michael X.、Smirnova Irina Y.、Snead Martin、Verhoeven Virginie J. M.、Verkicharla Pavan K.
    • Journal Title

      Investigative Opthalmology & Visual Science

      Volume: 64 Issue: 6 Pages: 3-3

    • DOI

      10.1167/iovs.64.6.3

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Microperimetry in Retinal Diseases2023

    • Author(s)
      Horie Shintaro、Giulia Corradetti、Esmaeilkhanian Houri、Sadda SriniVas R.、Cheung Chui Ming Gemmy、Ham Yeji、Chang Andrew、Takahashi Tomonari、Ohno-Matsui Kyoko
    • Journal Title

      Asia-Pacific Journal of Ophthalmology

      Volume: 12 Issue: 2 Pages: 211-227

    • DOI

      10.1097/apo.0000000000000597

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Efficacy of lutein supplements on macular pigment optical density in highly myopic individuals: A randomized controlled trial2023

    • Author(s)
      Yoshida Takeshi、Takagi Yasutaka、Igarashi-Yokoi Tae、Ohno-Matsui Kyoko
    • Journal Title

      Medicine

      Volume: 102 Issue: 12 Pages: e33280-e33280

    • DOI

      10.1097/md.0000000000033280

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed
  • [Journal Article] LONGITUDINAL STUDY OF CHANGES IN INNER SCLERAL CURVATURE PATTERNS AND DEVELOPMENT OF POSTERIOR STAPHYLOMAS IN HIGHLY MYOPIC EYES OF CHILDREN AND ADOLESCENTS2023

    • Author(s)
      Chen Changyu、Du Ran、Xie Shiqi、Lu Hongshuang、Xiong Jianping、Wang Yining、Nakao Noriko、Takahashi Hiroyuki、Igarashi-Yokoi Tae、Kamoi Koju、Uramoto Kengo、Ohno-Matsui Kyoko
    • Journal Title

      Retina

      Volume: 43 Issue: 3 Pages: 454-463

    • DOI

      10.1097/iae.0000000000003681

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Hospital-based study of risk factors associated with development of myopic macular neovascularization in highly myopic eyes2023

    • Author(s)
      Du Ran、Xie Shiqi、Lu Hongshuang、Chen Changyu、Xiong Jianping、Uramoto Kengo、Takahashi Hiroyuki、Onishi Yuka、Kamoi Koju、Nakao Noriko、Fang Yuxin、Ohno-Matsui Kyoko
    • Journal Title

      Ophthalmic Research

      Volume: 66 Issue: 1 Pages: 293-300

    • DOI

      10.1159/000527183

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed
  • [Journal Article] IMI Pathologic Myopia2021

    • Author(s)
      Ohno-Matsui Kyoko、Wu Pei-Chang、Yamashiro Kenji、Vutipongsatorn Kritchai、Fang Yuxin、Cheung Chui Ming Gemmy、Lai Timothy Y. Y.、Ikuno Yasushi、Cohen Salomon Yves、Gaudric Alain、Jonas Jost B.
    • Journal Title

      Investigative Opthalmology & Visual Science

      Volume: 62 Issue: 5 Pages: 5-5

    • DOI

      10.1167/iovs.62.5.5

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Novel Paravascular Lesions with Abnormal Autofluorescence in Pathologic Myopia2021

    • Author(s)
      Fang Yuxin、Ishida Tomoka、Du Ran、Xie Shiqi、Igarashi-Yokoi Tae、Yoshida Takeshi、Watanabe Takashi、Onishi Yuka、Ohno-Matsui Kyoko
    • Journal Title

      Ophthalmology

      Volume: 128 Issue: 3 Pages: 477-480

    • DOI

      10.1016/j.ophtha.2020.07.044

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] CLINICAL AND MORPHOLOGIC FEATURES OF POSTERIOR STAPHYLOMA EDGES BY ULTRA-WIDEFIELD IMAGING IN PATHOLOGIC MYOPIA2021

    • Author(s)
      Liu Lillian、Fang Yuxin、Igarashi-Yokoi Tae、Takahashi Hiroyuki、Ohno-Matsui Kyoko
    • Journal Title

      Retina

      Volume: 41 Issue: 11 Pages: 2278-2287

    • DOI

      10.1097/iae.0000000000003231

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Rapid and spontaneous resolution of hemorrhagic macular hole retinal detachment and subretinal hemorrhages in an eye with pathologic myopia: a case report2020

    • Author(s)
      Ito Taiju、Igarashi-Yokoi Tae、Shinohara Kosei、Yoshida Takeshi、Ohno-Matsui Kyoko
    • Journal Title

      BMC Ophthalmology

      Volume: 20 Issue: 1 Pages: 385-385

    • DOI

      10.1186/s12886-020-01653-0

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] CLINICAL FEATURES OF PATCHY CHORIORETINAL ATROPHY IN PATHOLOGIC MYOPIA2020

    • Author(s)
      Du Ran、Fang Yuxin、Jonas Jost B.、Yokoi Tae、Takahashi Hiroyuki、Uramoto Kengo、Kamoi Koju、Yoshida Takeshi、Ohno-Matsui Kyoko
    • Journal Title

      Retina

      Volume: 40 Issue: 5 Pages: 951-959

    • DOI

      10.1097/iae.0000000000002575

    • Related Report
      2020 Annual Research Report 2019 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] RIDGE-SHAPED MACULA IN YOUNG MYOPIC PATIENTS AND ITS DIFFERENTIATION FROM TYPICAL DOME-SHAPED MACULA IN ELDERLY MYOPIC PATIENTS2020

    • Author(s)
      Xu Xian、Fang Yuxin、Jonas Jost B.、Du Ran、Shinohara Kosei、Tanaka Noriko、Yokoi Tae、Onishi Yuka、Uramoto Kengo、Kamoi Koju、Yoshida Takeshi、Ohno-Matsui Kyoko
    • Journal Title

      Retina

      Volume: 40 Issue: 2 Pages: 1-1

    • DOI

      10.1097/iae.0000000000002395

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] DEVELOPMENT OF MACULAR ATROPHY AFTER PARS PLANA VITRECTOMY FOR MYOPIC TRACTION MACULOPATHY AND MACULAR HOLE RETINAL DETACHMENT IN PATHOLOGIC MYOPIA2019

    • Author(s)
      Fang Yuxin、Yokoi Tae、Shimada Noriaki、Du Ran、Shinohara Kosei、Takahashi Hiroyuki、Uramoto Kengo、Ohno-Matsui Kyoko
    • Journal Title

      Retina

      Volume: - Issue: 10 Pages: 1881-1893

    • DOI

      10.1097/iae.0000000000002709

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Ultra-Widefield Optical Coherence Tomographic Imaging of Posterior Vitreous in Eyes With High Myopia2019

    • Author(s)
      Takahashi Hiroyuki、Tanaka Noriko、Shinohara Kosei、Yokoi Tae、Yoshida Takeshi、Uramoto Kengo、Ohno-Matsui Kyoko
    • Journal Title

      American Journal of Ophthalmology

      Volume: 206 Pages: 102-112

    • DOI

      10.1016/j.ajo.2019.03.011

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Current and emerging pharmaceutical interventions for myopia2019

    • Author(s)
      Vutipongsatorn Kritchai、Yokoi Tae、Ohno-Matsui Kyoko
    • Journal Title

      British Journal of Ophthalmology

      Volume: 103 Issue: 11 Pages: 1539-1548

    • DOI

      10.1136/bjophthalmol-2018-313798

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] ABRUPTLY EMERGING VESSELS IN EYES WITH MYOPIC PATCHY CHORIORETINAL ATROPHY2019

    • Author(s)
      Xie Shiqi、Fang Yuxin、Du Ran、Yokoi Tae、Takahashi Hiroyuki、Uramoto Kengo、Yoshida Takeshi、Ohno-Matsui Kyoko
    • Journal Title

      Retina

      Volume: - Issue: 7 Pages: 1215-1223

    • DOI

      10.1097/iae.0000000000002630

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] FUNCTIONAL AND STRUCTURAL OUTCOMES AFTER FOVEA-SPARING INTERNAL LIMITING MEMBRANE PEELING FOR MYOPIC MACULAR RETINOSCHISIS BY MICROPERIMETRY2019

    • Author(s)
      Shinohara Kosei、Shimada Noriaki、Takase Hiroshi、Ohno-Matsui Kyoko
    • Journal Title

      Retina

      Volume: - Issue: 8 Pages: 1500-1511

    • DOI

      10.1097/iae.0000000000002627

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] OCT-Based Diagnostic Criteria for Different Stages of Myopic Maculopathy2019

    • Author(s)
      Fang Yuxin、Du Ran、Nagaoka Natsuko、Yokoi Tae、Shinohara Kosei、Xu Xian、Takahashi Hiroyuki、Onishi Yuka、Yoshida Takeshi、Ohno-Matsui Kyoko
    • Journal Title

      Ophthalmology

      Volume: 126 Issue: 7 Pages: 1018-1032

    • DOI

      10.1016/j.ophtha.2019.01.012

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Posterior staphylomas and scleral curvature in highly myopic children and adolescents investigated by ultra-widefield optical coherence tomography2019

    • Author(s)
      Tanaka Noriko、Shinohara Kosei、Yokoi Tae、Uramoto Kengo、Takahashi Hiroyuki、Onishi Yuka、Horie Shintaro、Yoshida Takeshi、Ohno-Matsui Kyoko
    • Journal Title

      PLOS ONE

      Volume: 14 Issue: 6 Pages: 0218107-0218107

    • DOI

      10.1371/journal.pone.0218107

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] CORRELATIONS BETWEEN EXPERIMENTAL MYOPIA MODELS AND HUMAN PATHOLOGIC MYOPIA2019

    • Author(s)
      Vutipongsatorn Kritchai、Nagaoka Natsuko、Yokoi Tae、Yoshida Takeshi、Kamoi Koju、Horie Shintaro、Uramoto Kengo、Hirata Akira、Occelli Laurence M.、Petersen-Jones Simon M.、Montiani-Ferreira Fabiano、Cases Olivier、Kozyraki Renata、Jonas Jost B.、Ohno-Matsui Kyoko
    • Journal Title

      Retina

      Volume: 39 Issue: 4 Pages: 621-635

    • DOI

      10.1097/iae.0000000000002426

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] IMI ? Defining and Classifying Myopia: A Proposed Set of Standards for Clinical and Epidemiologic Studies2019

    • Author(s)
      Flitcroft Daniel Ian、He Mingguang、Jonas Jost B.、Jong Monica、Naidoo Kovin、Ohno-Matsui Kyoko、Rahi Jugnoo、Resnikoff Serge、Vitale Susan、Yannuzzi Lawrence
    • Journal Title

      Investigative Opthalmology & Visual Science

      Volume: 60 Issue: 3 Pages: M20-M20

    • DOI

      10.1167/iovs.18-25957

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Cilioretinal Arteries and Cilioretinal Veins in Eyes with Pathologic Myopia2019

    • Author(s)
      Watanabe Takashi、Kasahara Kaori、Futagami Soh、Fang Yuxin、Du Ran、Moriyama Muka、Uramoto Kengo、Yokoi Tae、Onishi Yuka、Yoshida Takeshi、Kamoi Koju、Jonas Jost B.、Ohno-Matsui Kyoko
    • Journal Title

      Scientific Reports

      Volume: 9 Issue: 1 Pages: 110-112

    • DOI

      10.1038/s41598-019-38616-5

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Update in myopia and treatment strategy of atropine use in myopia control2019

    • Author(s)
      Wu Pei-Chang、Chuang Meng-Ni、Choi Jessy、Chen Huan、Wu Grace、Ohno-Matsui Kyoko、Jonas Jost B、Cheung Chui Ming Gemmy
    • Journal Title

      Eye

      Volume: 33 Issue: 1 Pages: 3-13

    • DOI

      10.1038/s41433-018-0139-7

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] RIDGE-SHAPED MACULA PROGRESSING PARALLEL TO BRUCH MEMBRANE DEFECTS AND MACULAR SUPRACHOROIDAL CAVITATION2018

    • Author(s)
      Fang Yuxin、Du Ran、Jonas Jost B.、Watanabe Takashi、Uramoto Kengo、Yokoi Tae、Onishi Yuka、Yoshida Takeshi、Kamoi Koju、Ohno-Matsui Kyoko
    • Journal Title

      Retina

      Volume: 12 Issue: 3 Pages: 1-1

    • DOI

      10.1097/iae.0000000000002404

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] FIVE-YEAR OUTCOMES OF INTRAVITREAL RANIBIZUMAB FOR CHOROIDAL NEOVASCULARIZATION IN PATIENTS WITH PATHOLOGIC MYOPIA2018

    • Author(s)
      Onishi Yuka、Yokoi Tae、Kasahara Kaori、Yoshida Takeshi、Nagaoka Natsuko、Shinohara Kosei、Kaneko Yuichiro、Suga Mitsuki、Uramoto Kengo、Ohno-Tanaka Akiko、Ohno-Matsui Kyoko
    • Journal Title

      Retina

      Volume: ー Issue: 7 Pages: 1-1

    • DOI

      10.1097/iae.0000000000002164

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] CLINICAL FEATURES OF LACQUER CRACKS IN EYES WITH PATHOLOGIC MYOPIA2018

    • Author(s)
      Xu Xian、Fang Yuxin、Uramoto Kengo、Nagaoka Natsuko、Shinohara Kosei、Yokoi Tae、Tanaka Noriko、Ohno-Matsui Kyoko
    • Journal Title

      Retina

      Volume: ー Issue: 7 Pages: 1-1

    • DOI

      10.1097/iae.0000000000002168

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] POSTERIOR STAPHYLOMAS IN EYES WITH RETINITIS PIGMENTOSA WITHOUT HIGH MYOPIA2018

    • Author(s)
      Xu Xian、Fang Yuxin、Yokoi Tae、Shinohara Kosei、Hirakata Akito、Iwata Takeshi、Tsunoda Kazushige、Jonas Jost B.、Ohno-Matsui Kyoko
    • Journal Title

      Retina

      Volume: ー Issue: 7 Pages: 1-1

    • DOI

      10.1097/iae.0000000000002180

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Possible connection of short posterior ciliary arteries to?choroidal?neovascularisations in eyes with pathologic myopia2018

    • Author(s)
      Ishida Tomoka、Watanabe Takashi、Yokoi Tae、Shinohara Kosei、Ohno-Matsui Kyoko
    • Journal Title

      British Journal of Ophthalmology

      Volume: 103 Issue: 4 Pages: 457-462

    • DOI

      10.1136/bjophthalmol-2018-312015

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Presentation] Intervortex vein anastomoses in pathologic myopia.2023

    • Author(s)
      Ohno-Matsui K
    • Organizer
      30th Anniversary of The Retina Center at Pali Momi & Hawaii Macula and Retina Institute
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Imaging advances in pathologic myopia.2022

    • Author(s)
      Ohno-Matsui K
    • Organizer
      The 15th Asia-Pacific Vitreo-retina Society
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Posterior staphyloma in pathologic myopia.2022

    • Author(s)
      Ohno-Matsui K
    • Organizer
      第36回メキシコ眼科学会,
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Structural abnormalities in the papillary and peripapillary areas and corresponding vf defects in eyes with pathologic myopia.2022

    • Author(s)
      Ohno-Matsui K
    • Organizer
      AAO2022
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Pathologic Myopia.2022

    • Author(s)
      Ohno-Matsui K
    • Organizer
      コロンビア大学招待講演
    • Related Report
      2021 Annual Research Report
    • Invited
  • [Presentation] Abnormalities of choroidal vasculature in pathologic myopia.2022

    • Author(s)
      Ohno-Matsui K
    • Organizer
      World Ophthalmology Congress 2022
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Intervortex anastomoses in pathologic myopia.2022

    • Author(s)
      Ohno-Matsui K
    • Organizer
      第17回 Retina en Platique.
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Punctate Inner Choroidopathy in Pathologic Myopia.2022

    • Author(s)
      Ohno-Matsui K
    • Organizer
      14th Asia-Pacific Vitreo-retina Society (APVRS) Congress
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Pathologic myopia.2022

    • Author(s)
      Ohno-Matsui K
    • Organizer
      Retina Festival 2021- Johns Hopkins CME.
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Ultra-widefield optical coherence tomographic imaging of pathologic myopia2022

    • Author(s)
      Ohno-Matsui K
    • Organizer
      第14回日中韓眼科ジョイントミーティング
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Punctate Inner choroidopathy in pathologic myopia.2021

    • Author(s)
      Ohno-Matsui K
    • Organizer
      Asia Pacific Retina Imaging Society (APRIS)
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] State-of-the-art imaging of pathologic myopia.2021

    • Author(s)
      Ohno-Matsui K
    • Organizer
      2021 International Conference on Clinical Research in Ophthalmology
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Novel paravascular lesions with abnormal autofluorescence in eyes with pathologic myopia.2020

    • Author(s)
      Ohno-Matsui K
    • Organizer
      第44回米国黄斑会議 The Macula Society
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Ultra wide-field imaging of pathologic myopia.2020

    • Author(s)
      Ohno-Matsui K
    • Organizer
      Ultra wide-field imaging of pathologic myopia.
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Imaging of pathologic myopia.2020

    • Author(s)
      Ohno-Matsui K
    • Organizer
      Daalhousie University Department of Opthalmology and Visual Sciences
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Book] マルチモーダルイメージングでとらえる 広角眼底アトラス2023

    • Author(s)
      大野京子, 吉田武史, 堀江真太郎, 鴨居功樹
    • Total Pages
      312
    • Publisher
      三輪書店
    • ISBN
      9784895907750
    • Related Report
      2021 Annual Research Report
  • [Book] Pathologic Myopia 2nd edition2021

    • Author(s)
      Spaide RF, Ohno-Matsui K, Yannuzzi LA
    • Total Pages
      478
    • Publisher
      Springer
    • ISBN
      9783030743338
    • Related Report
      2021 Annual Research Report
  • [Book] Atlas of Pathologic Myopia.2020

    • Author(s)
      Ohno-Matsui K
    • Total Pages
      114
    • Publisher
      Springer
    • ISBN
      9789811542602
    • Related Report
      2020 Annual Research Report

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Published: 2019-04-18   Modified: 2024-01-30  

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