• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Elucidating the primate basis of neurobiological mechanisms underlying developmental disorders

Research Project

Project/Area Number 19H05467
Research Category

Grant-in-Aid for Specially Promoted Research

Allocation TypeSingle-year Grants
Review Section Biological Sciences
Research InstitutionKyoto University

Principal Investigator

Takada Masahiko  京都大学, ヒト行動進化研究センター, 研究員 (00236233)

Co-Investigator(Kenkyū-buntansha) 二宮 太平  生理学研究所, システム脳科学研究領域, 助教 (40586343)
橋本 亮太  大阪大学, 大学院医学系研究科, 招へい教授 (10370983)
松本 正幸  筑波大学, 医学医療系, 研究員 (50577864)
Project Period (FY) 2019-04-23 – 2024-03-31
Project Status Completed (Fiscal Year 2023)
Budget Amount *help
¥508,820,000 (Direct Cost: ¥391,400,000、Indirect Cost: ¥117,420,000)
Fiscal Year 2023: ¥91,000,000 (Direct Cost: ¥70,000,000、Indirect Cost: ¥21,000,000)
Fiscal Year 2022: ¥91,000,000 (Direct Cost: ¥70,000,000、Indirect Cost: ¥21,000,000)
Fiscal Year 2021: ¥91,000,000 (Direct Cost: ¥70,000,000、Indirect Cost: ¥21,000,000)
Fiscal Year 2020: ¥123,500,000 (Direct Cost: ¥95,000,000、Indirect Cost: ¥28,500,000)
Fiscal Year 2019: ¥112,320,000 (Direct Cost: ¥86,400,000、Indirect Cost: ¥25,920,000)
Keywords発達障害 / 社会的行動 / 神経ネットワーク / 認知ゲノム / 霊長類
Outline of Research at the Start

本研究では、ヒトに近い霊長類動物を用いて、社会性およびその破綻としての発達障害に関わる神経生物学的機構の解明を目指す。具体的には、社会性の制御に関わる遺伝子と神経回路を同定し、それらの機能を明らかにするため、集団あるいは集団の中の個体による社会的行動、社会的行動を規定する神経ネットワーク活動、更に、神経ネットワーク活動を支配する認知ゲノム発現の生物学的トライアングル連関のメカニズムを検証する。

Outline of Final Research Achievements

In the present research project, we have elucidated the primate basis of neurobiological mechanisms underlying the social mind and developmental disorders caused by its disruption. Employing monkeys (macaques, marmosets) as primate models, a paradigm shift from previous “individual-level life science” to novel “society/group-level life science”was attempted. We successfully adopted a wide variety of innovative technologies as well as the excellent research environment at the Primate Research Institute, Kyoto University. On marmosets of which social and familial activities are well developed, we analyzed the behavioral pattern of a group including a developmental disorder model and, also, the specific behavioral pattern of the model within a group. In macaques who possess higher cognitive functions, on the other hand, cognitive deficits and interactions with others of a developmental disorder model were evaluated at both the behavioral and the electrophysiological levels.

Academic Significance and Societal Importance of the Research Achievements

本研究によって発信される成果は、集団的視座から認知行動や精神活動を包括的に捉え、その一様態としての自閉スペクトラム症や統合失調症などの発達障害における行動特性の理解と、発達障害者の集団内における行動の理解に繋がるだけでなく、いじめや自殺など、青少年における重大な社会問題に対して、システム神経科学と精神医学の両面から切り込み、問題の早期発見や介入・治療法の開発に発展することが期待される。また、ヒトと霊長類モデルの双方から得られるデータを相互補完的に活用することにより、発達障害の神経回路基盤やゲノム基盤の解明をとおして介入・治療ターゲットの同定や臨床的検証に資することが期待できると考える。

Assessment Rating
Ex-post Assessment Comments (Rating)

A-:  In light of the aim of introducing the research area into the research categories, expected outcomes of research have been produced on the whole though the progress in a part of the research has been delayed.

Assessment Rating
Interim Assessment Comments (Rating)

A: In light of the aim of introducing the research area into the research categories, the expected progress has been made in research.

Report

(11 results)
  • 2024 Ex-post Assessment (Comments) ( PDF )
  • 2023 Annual Research Report   Final Research Report ( PDF )
  • 2022 Annual Research Report
  • 2021 Abstract (Interim Assessment) ( PDF )   Annual Research Report   Interim Assessment (Comments) ( PDF )
  • 2020 Annual Research Report
  • 2019 Abstract ( PDF )   Comments on the Screening Results ( PDF )   Annual Research Report
  • Research Products

    (251 results)

All 2024 2023 2022 2021 2020 2019 2018 Other

All Int'l Joint Research (3 results) Journal Article (100 results) (of which Int'l Joint Research: 25 results,  Peer Reviewed: 100 results,  Open Access: 96 results) Presentation (127 results) (of which Int'l Joint Research: 31 results,  Invited: 12 results) Book (9 results) Remarks (11 results) Funded Workshop (1 results)

  • [Int'l Joint Research] Center HM Cinac(スペイン)

    • Related Report
      2023 Annual Research Report
  • [Int'l Joint Research] University of Cambridge(英国)

    • Related Report
      2023 Annual Research Report
  • [Int'l Joint Research] National Institutes Health(米国)

    • Related Report
      2023 Annual Research Report
  • [Journal Article] Longitudinal reduction in brain volume in patients with schizophrenia and its association with cognitive function2024

    • Author(s)
      Yamazaki R, Matsumoto J, Ito S, Nemoto K, Fukunaga M, Hashimoto N, Kodaka F, Takano H, Hasegawa N, Yasuda Y, Fujimoto M, Yamamori H, Watanabe Y, Miura K, Hashimoto R
    • Journal Title

      Neuropsychopharmacology Reports

      Volume: 44 Issue: 1 Pages: 206-215

    • DOI

      10.1002/npr2.12423

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Visual salience is affected in participants with schizophrenia during free-viewing2024

    • Author(s)
      Yoshida M, Miura K, Fujimoto M, Yamamori H, Yasuda Y, Iwase M, Hashimoto R
    • Journal Title

      Scientific Reports

      Volume: 14 Issue: 1 Pages: 4606-4606

    • DOI

      10.1038/s41598-024-55359-0

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Environmental context-dependent activation of dopamine neurons via putative amygdala-nigra pathway in macaques.2023

    • Author(s)
      Maeda K; Inoue K; Takada M; Hikosaka O
    • Journal Title

      Nature Communications

      Volume: 14 Issue: 1 Pages: 2282-2282

    • DOI

      10.1038/s41467-023-37584-9

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] BBB opening with focused ultrasound in nonhuman primates and Parkinson's disease patients: targeted AAV vector delivery and PET imaging.2023

    • Author(s)
      Blesa J; Pineda-Pardo JA; Inoue K; Gasca-Salas C; Balzano T; del Rey NL-G; Reinares-Sebastian A; Esteban-Garcia N; Rodriguez-Rojas R; Marquez R; Ciorraga M; del Alamo M; Garcia-Canamaque L; de Aguiar SR; Rachmilevitch I; Trigo-Damas I; Takada M; Obeso JA
    • Journal Title

      Science Advances

      Volume: 9 Issue: 16 Pages: 16-16

    • DOI

      10.1126/sciadv.adf4888

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Reorganization of corticospinal projections after prominent recovery of finger dexterity from partial spinal cord injury in macaque monkeys.2023

    • Author(s)
      Sawada M, Yoshino K, Ninomiya T, Oishi T, Yamashita T, Onoe H, Takada M, Nishimura Y, Isa T
    • Journal Title

      eNeuro

      Volume: 10 Issue: 8 Pages: 209-223

    • DOI

      10.1523/eneuro.0209-23.2023

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] A mosaic adeno-associated virus vector as a versatile tool that exhibits high levels of transgene expression and neuron specificity in primate brain.2023

    • Author(s)
      Kimura K; Nagai Y; Hatanaka G; Fang Y; Tanabe S; Zheng A; Fujiwara M; Nakano M; Hori Y; Takeuchi RF; Inagaki M; Minamimoto T; Fujita I; Inoue K; Takada M
    • Journal Title

      Nature Communications

      Volume: 14 Issue: 1 Pages: 4762-4762

    • DOI

      10.1038/s41467-023-40436-1

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Multimodal imaging for validation and optimization of ion channel-based chemogenetics in nonhuman primates2023

    • Author(s)
      Yuki Hori, Yuji Nagai, Yukiko Hori, Kei Oyama, Koki Mimura, Toshiyuki Hirabayashi, Ken-ichi Inoue, Masayuki Fujinaga, Ming-Rong Zhang, Masahiko Takada, Makoto Higuchi, Takafumi Minamimoto
    • Journal Title

      Journal of Neuroscience

      Volume: 43 Issue: 39 Pages: 6619-6627

    • DOI

      10.1523/jneurosci.0625-23.2023

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Reward expectation enhances action-related activity of nigral dopaminergic and two striatal output pathways2023

    • Author(s)
      Rios Alain、Nonomura Satoshi、Kato Shigeki、Yoshida Junichi、Matsushita Natsuki、Nambu Atsushi、Takada Masahiko、Hira Riichiro、Kobayashi Kazuto、Sakai Yutaka、Kimura Minoru、Isomura Yoshikazu
    • Journal Title

      Communications Biology

      Volume: 6 Issue: 1 Pages: 914-914

    • DOI

      10.1038/s42003-023-05288-x

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Chemogenetic dissection of a prefrontal-hypothalamic circuit for socially subjective reward valuation in macaques2023

    • Author(s)
      Noritake A, Ninomiya T, Kobayashi K, Isoda M
    • Journal Title

      Nature Communications

      Volume: 14 Issue: 1 Pages: 4372-4372

    • DOI

      10.1038/s41467-023-40143-x

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Subcortical volumetric alterations in four major psychiatric disorders: a mega-analysis study of 5604 subjects and a volumetric data-driven approach for classification.2023

    • Author(s)
      N. Okada,et al.
    • Journal Title

      Mol Psychiatry.

      Volume: 28 Issue: 12 Pages: 5206-5216

    • DOI

      10.1038/s41380-023-02141-9

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Cerebral cortical structural alteration patterns across four major psychiatric disorders in 5549 individuals.2023

    • Author(s)
      J. Matsumoto,M. Fukunaga,K. Miura,K. Nemoto K,N. Okada, et al.
    • Journal Title

      Mol Psychiatry

      Volume: 28 Issue: 11 Pages: 4915-4923

    • DOI

      10.1038/s41380-023-02224-7

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Longitudinal characteristics of insight and clinical factors in patients with schizophrenia2023

    • Author(s)
      Sakai Yoshie、Ito Satsuki、Matsumoto Junya、Yasuda Yuka、Yamamori Hidenaga、Fujimoto Michiko、Hasegawa Naomi、Ishimaru Keiichiro、Miura Kenichiro、Hashimoto Ryota
    • Journal Title

      Neuropsychopharmacology Reports

      Volume: 43 Issue: 3 Pages: 373-381

    • DOI

      10.1002/npr2.12356

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Chemogenetic attenuation of cortical seizures in nonhuman primates2023

    • Author(s)
      Miyakawa Naohisa、Nagai Yuji、Hori Yukiko、Mimura Koki、Orihara Asumi、Oyama Kei、Matsuo Takeshi、Inoue Ken-ichi、Suzuki Takafumi、Hirabayashi Toshiyuki、Suhara Tetsuya、Takada Masahiko、Higuchi Makoto、Kawasaki Keisuke、Minamimoto Takafumi
    • Journal Title

      Nature Communications

      Volume: 14 Issue: 1 Pages: 1-11

    • DOI

      10.1038/s41467-023-36642-6

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Genetics of autism spectrum disorders and future direction.2023

    • Author(s)
      Yasuda Y, Matsumoto J, Miura K, Hasegawa N, Hashimoto R.
    • Journal Title

      Journal of Human Genetics

      Volume: 63 Issue: 3 Pages: 193-197

    • DOI

      10.1038/s10038-022-01076-3

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Chemogenetic Disconnection between the Orbitofrontal Cortex and the Rostromedial Caudate Nucleus Disrupts Motivational Control of Goal-Directed Action2022

    • Author(s)
      Oyama Kei、Hori Yukiko、Mimura Koki、Nagai Yuji、Eldridge Mark A. G.、Saunders Richard C.、Miyakawa Naohisa、Hirabayashi Toshiyuki、Hori Yuki、Inoue Ken-ichi、Suhara Tetsuya、Takada Masahiko、Higuchi Makoto、Richmond Barry J.、Minamimoto Takafumi
    • Journal Title

      The Journal of Neuroscience

      Volume: 42 Issue: 32 Pages: 6267-6275

    • DOI

      10.1523/jneurosci.0229-22.2022

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Cognitive genomics of learning delay and low level of social performance monitoring in macaque2022

    • Author(s)
      Ninomiya T, Noritake A, Tatsumoto S, Go Y, Isoda M
    • Journal Title

      Scientific Reports

      Volume: 12 Issue: 1 Pages: 16539-16539

    • DOI

      10.1038/s41598-022-20948-4

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Origin of Multisynaptic Corticospinal Pathway to Forelimb Segments in Macaques and Its Reorganization After Spinal Cord Injury2022

    • Author(s)
      Ninomiya Taihei、Nakagawa Hiroshi、Inoue Ken-ichi、Nishimura Yukio、Oishi Takao、Yamashita Toshihide、Takada Masahiko
    • Journal Title

      Frontiers in Neural Circuits

      Volume: 16 Pages: 847100-847100

    • DOI

      10.3389/fncir.2022.847100

    • Related Report
      2022 Annual Research Report 2021 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Relationship between autistic traits and social functioning in healthy individuals2022

    • Author(s)
      Demizu Yuria、Matsumoto Junya、Yasuda Yuka、Ito Satsuki、Miura Kenichiro、Yamamori Hidenaga、Fujimoto Michiko、Hasegawa Naomi、Ishimaru Keiichiro、Hashimoto Ryota
    • Journal Title

      Neuropsychopharmacology Reports

      Volume: 42 Issue: 2 Pages: 226-229

    • DOI

      10.1002/npr2.12249

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Transdiagnostic comparisons of intellectual abilities and work outcome in patients with mental disorders: multicentre study2022

    • Author(s)
      Sumiyoshi C, Ohi K, Fujino H, Yamamori H, Fujimoto M, Yasuda Y, Uno Y, Takahashi J, Morita K, Katsuki A, Yamamoto M, Okahisa Y, Sata A, Katsumoto E, Koeda M, Hirano Y, Nakataki M, Matsumoto J, Miura K, Hashimoto N, Makinodan M, Takahashi T, Nemoto K, Kishimoto T, Suzuki M, Sumiyoshi T, Hashimoto R.
    • Journal Title

      BJPsych Open .

      Volume: 8(4) Issue: 4 Pages: 1-10

    • DOI

      10.1192/bjo.2022.50

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Toward recovery in schizophrenia: Current concepts, findings, and future research directions.2022

    • Author(s)
      Onitsuka T, Hirano Y, Nakazawa T, Ichihashi K, Miura K, Inada K, Mitoma R, Yasui-Furukori N, Hashimoto R.
    • Journal Title

      Psychiatry and Clinical Neurosciences

      Volume: 76 Pages: 282-291

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] A Noninvasive Method for Monitoring Breathing Patterns in Nonhuman Primates Using a Nasal Thermosensor2022

    • Author(s)
      Kunimatsu J, Akiyama Y, Toyoshima O, Matsumoto M
    • Journal Title

      eNeuro

      Volume: 9 Issue: 6 Pages: ENEURO.0352-22.2022

    • DOI

      10.1523/eneuro.0352-22.2022

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Conservation of the Direct and Indirect Pathway Dichotomy in Mouse Caudal Striatum With Uneven Distribution of Dopamine Receptor D1- and D2-Expressing Neurons2022

    • Author(s)
      Ogata Kumiko、Kadono Fuko、Hirai Yasuharu、Inoue Ken-ichi、Takada Masahiko、Karube Fuyuki、Fujiyama Fumino
    • Journal Title

      Frontiers in Neuroanatomy

      Volume: 16 Pages: 1-22

    • DOI

      10.3389/fnana.2022.809446

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Chronic Behavioral Manipulation via Orally Delivered Chemogenetic Actuator in Macaques2022

    • Author(s)
      Oyama Kei、Hori Yukiko、Nagai Yuji、Miyakawa Naohisa、Mimura Koki、Hirabayashi Toshiyuki、Inoue Ken-ichi、Takada Masahiko、Higuchi Makoto、Minamimoto Takafumi
    • Journal Title

      The Journal of Neuroscience

      Volume: 42 Issue: 12 Pages: 2552-2561

    • DOI

      10.1523/jneurosci.1657-21.2021

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Claustrum mediates bidirectional and reversible control of stress-induced anxiety responses.2022

    • Author(s)
      Niu M, Kasai A, Tanuma M, Seiriki K, Igarashi H, Kuwaki T, Nagayasu K, Miyaji K, Ueno H, Tanabe W, Seo K, Yokoyama R, Ohkubo J, Ago Y, Hayashida M, Inoue KI, Takada M, Yamaguchi S, Nakazawa T, Kaneko S, Okuno H, Yamanaka A, Hashimoto H.
    • Journal Title

      Science Advances

      Volume: 8 Issue: 11

    • DOI

      10.1126/sciadv.abi6375

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] A multisynaptic pathway from the ventral midbrain toward spinal motoneurons in monkeys2022

    • Author(s)
      Suzuki Michiaki、Inoue Ken‐ichi、Nakagawa Hiroshi、Ishida Hiroaki、Kobayashi Kenta、Isa Tadashi、Takada Masahiko、Nishimura Yukio
    • Journal Title

      The Journal of Physiology

      Volume: 600 Issue: 7 Pages: 1731-1752

    • DOI

      10.1113/jp282429

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Perturbation of monoamine metabolism and enhanced fear responses in mice defective in the regeneration of tetrahydrobiopterin2022

    • Author(s)
      K Miyajima, Y Sudo, S Sanechika, Y Hara, M Horiguchi, F Xu, M Suzuki, S Hara, K Tanda, K Inoue, M Takada, N Yoshioka, H Takebayashi, M Mori-Kojima, M Sugimoto, C Sumi-Ichinose, K Kondo, K Takao, T Miyakawa, H Ichinose
    • Journal Title

      J Neurochemistry

      Volume: 161(2) Issue: 2 Pages: 129-145

    • DOI

      10.1111/jnc.15600

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Rapid processing of threatening faces in the amygdala of nonhuman primates: subcortical inputs and dural roles2022

    • Author(s)
      Mikio Inagaki, Ken-ichi Inoue, Soshi Tanabe, Kei Kimura, Masahiko Takada, Ichiro Fujita
    • Journal Title

      Cerebral Cortex

      Volume: - Issue: 3 Pages: 1-21

    • DOI

      10.1093/cercor/bhac109

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Oxytocin ameliorates impaired social behavior in a mouse model of 3q29 deletion syndrome2022

    • Author(s)
      Takemoto Tomoya、Baba Masayuki、Yokoyama Kazumasa、Kitagawa Kohei、Nagayasu Kazuki、Ago Yukio、Seiriki Kaoru、Hayata-Takano Atsuko、Kasai Atsushi、Mori Daisuke、Ozaki Norio、Takuma Kazuhiro、Hashimoto Ryota、Hashimoto Hitoshi、Nakazawa Takanobu
    • Journal Title

      Molecular Brain

      Volume: 15 Issue: 1 Pages: 26-26

    • DOI

      10.1186/s13041-022-00915-w

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Trends in Big Data Analyses by Multicenter Collaborative Translational Research in Psychiatry2022

    • Author(s)
      Toshiaki Onitsuka, Yoji Hirano, Kiyotaka Nemoto, Naoki Hashimoto, Itaru Kushima, Daisuke Koshiyama, Michihiko Koeda, Tsutomu Takahashi, Yoshihiro Noda, Junya Matsumoto, Kenichiro Miura, Takanobu Nakazawa, Takatoshi Hikida, Kiyoto Kasai, Norio Ozaki, Ryota Hashimoto
    • Journal Title

      Psychiatry and Clinical Neurosciences

      Volume: 76 Issue: 1 Pages: 1-14

    • DOI

      10.1111/pcn.13311

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Chemogenetic dissection of the primate prefronto-subcortical pathways for working memory and decision-making2021

    • Author(s)
      Oyama Kei、Hori Yukiko、Nagai Yuji、Miyakawa Naohisa、Mimura Koki、Hirabayashi Toshiyuki、Inoue Ken-ichi、Suhara Tetsuya、Takada Masahiko、Higuchi Makoto、Minamimoto Takafumi
    • Journal Title

      Science Advances

      Volume: 7 Issue: 26 Pages: 1-9

    • DOI

      10.1126/sciadv.abg4246

    • NAID

      120007089253

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] An enhanced therapeutic effect of repetitive transcranial magnetic stimulation combined with antibody treatment in a primate model of spinal cord injury2021

    • Author(s)
      Yamanaka Hajime、Takata Yu、Nakagawa Hiroshi、Isosaka-Yamanaka Tomoko、Yamashita Toshihide、Takada Masahiko
    • Journal Title

      PLOS ONE

      Volume: 16 Issue: 6 Pages: e0252023-e0252023

    • DOI

      10.1371/journal.pone.0252023

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Retrograde Transgene Expression via Neuron-Specific Lentiviral Vector Depends on Both Species and Input Projection.2021

    • Author(s)
      Otsuka Y, Tsuge H, Uezono S, Tanabe S, Fujiwara M, Miwa M, Kato S, Nakamura K, Kobayashi K, Inoue K, Takada M
    • Journal Title

      Viruses

      Volume: 13(7) Issue: 7 Pages: 1387-1387

    • DOI

      10.3390/v13071387

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Altered dynamic information flow through the cortico-basal ganglia pathways mediates Parkinson’s disease symptoms.2021

    • Author(s)
      Chiken S, Takada M, Nambu A
    • Journal Title

      Cerebral Cortex

      Volume: 31(12) Issue: 12 Pages: 5363-5380

    • DOI

      10.1093/cercor/bhab164

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Single caudate neurons encode temporally discounted value for formulating motivation for action.2021

    • Author(s)
      Hori Y, Mimura K, Nagai Y, Fujimoto A, Oyama K, Kikuchi E, Inoue KI, Takada M, Suhara T, Richmond BJ, Minamimoto T.
    • Journal Title

      eLife

      Volume: 10 Pages: 61248-61248

    • DOI

      10.7554/elife.61248

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Microendoscopic calcium imaging of the primary visual cortex of behaving macaques.2021

    • Author(s)
      Oguchi M, Jiasen J, Yoshioka TW, Tanaka YR, Inoue K, Takada M, Kikusui T, Nomoto K, Sakagami M
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1 Pages: 17021-17021

    • DOI

      10.1038/s41598-021-96532-z

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Chemogenetic activation of nigrostriatal dopamine neurons in freely moving common marmosets.2021

    • Author(s)
      Mimura K, Nagai Y, Inoue K, Matsumoto J, Hori Y, Sato C, Kimura K, Okauchi T, Hirabayashi T, Nishijo H, Yahata N, Takada M, Suhara T, Higuchi M, Minamimoto T
    • Journal Title

      iScience

      Volume: 24(9) Issue: 9 Pages: 103066-103066

    • DOI

      10.1016/j.isci.2021.103066

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Chemogenetic sensory fMRI reveals behaviorally-relevant bidirectional changes in primate somatosensory network.2021

    • Author(s)
      Hirabayashi T, Nagai Y, Hori Y, Inoue KI, Aoki I, Takada M, Suhara T, Higuchi M, Minamimoto T.
    • Journal Title

      Neuron

      Volume: 109 Issue: 20 Pages: 3312-3322

    • DOI

      10.1016/j.neuron.2021.08.032

    • NAID

      120007166034

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Specific gene expression in unmyelinated dorsal root ganglion neurons in nonhuman primates by intranerve injection of adeno-associated virus 6 vector.2021

    • Author(s)
      Kudo M, Wupuer S, Fujiwara M, Saito Y, Kubota S, Inoue K, Takada M, Seki K
    • Journal Title

      Molecular Therapy - Methods & Clinical Development

      Volume: 23 Pages: 11-22

    • DOI

      10.1016/j.omtm.2021.07.009

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Laminar Organization of the Entorhinal Cortex in Macaque Monkeys Based on Cell-Type-Specific Markers and Connectivity2021

    • Author(s)
      Ohara Shinya、Yoshino Rintaro、Kimura Kei、Kawamura Taichi、Tanabe Soshi、Zheng Andi、Nakamura Shinya、Inoue Ken-ichi、Takada Masahiko、Tsutsui Ken-Ichiro、Witter Menno P.
    • Journal Title

      Frontiers in Neural Circuits

      Volume: 15 Pages: 790116-790116

    • DOI

      10.3389/fncir.2021.790116

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Live agent preference and social action monitoring in the macaque mid-superior temporal sulcus region2021

    • Author(s)
      Ninomiya T, Noritake A, Isoda M
    • Journal Title

      Proceedings of the National Academy of Sciences of the United States of America

      Volume: 118(44) Issue: 44

    • DOI

      10.1073/pnas.2109653118

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Positive association between insight and attitudes toward medication in Japanese patients with schizophrenia: Evaluation with the Schedule for Assessment of Insight ( <scp>SAI</scp> ) and the Drug Attitude Inventory ? 10 Questionnaire ( <scp>DAI</scp> ‐10)2021

    • Author(s)
      Ito Satsuki、Matsumoto Junya、Sakai Yoshie、Miura Kenichiro、Hasegawa Naomi、Yamamori Hidenaga、Ishimaru Keiichiro、Kim Yoshiharu、Hashimoto Ryota
    • Journal Title

      Psychiatry and Clinical Neurosciences

      Volume: 75 Issue: 5 Pages: 187-188

    • DOI

      10.1111/pcn.13215

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Polygenic Risk Scores Differentiating Schizophrenia From Bipolar Disorder Are Associated With Premorbid Intelligence in Schizophrenia Patients and Healthy Subjects2021

    • Author(s)
      Ohi Kazutaka、Nishizawa Daisuke、Sugiyama Shunsuke、Takai Kentaro、Kuramitsu Ayumi、Hasegawa Junko、Soda Midori、Kitaichi Kiyoyuki、Hashimoto Ryota、Ikeda Kazutaka、Shioiri Toshiki
    • Journal Title

      International Journal of Neuropsychopharmacology

      Volume: 24 Issue: 7 Pages: 562-569

    • DOI

      10.1093/ijnp/pyab014

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Association of adverse childhood experiences and precuneus volume with intrusive reexperiencing in autism spectrum disorder.2021

    • Author(s)
      Kitamura S, Makinodan M, Matsuoka K, Takahashi M, Yoshikawa H, Ishida R, Kishimoto N, Yasuno F, Yasuda Y, Hashimoto R, Miyasaka T, Kichikawa K, Kishimoto T
    • Journal Title

      Autism Research

      Volume: 14 Issue: 9 Pages: 1886-1895

    • DOI

      10.1002/aur.2558

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Methylation Analysis in Monozygotic Twins With Treatment-Resistant Schizophrenia and Discordant Responses to Clozapine.2021

    • Author(s)
      Kikuchi M, Nakazawa T, Kinoshita M, Yamamori H, Yasuda Y, Fujimoto M, Hashimoto R, Numata S
    • Journal Title

      Frontiers in Psychiatry

      Volume: 12 Pages: 734606-734606

    • DOI

      10.3389/fpsyt.2021.734606

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Multiple alterations in glutamatergic transmission and dopamine D2 receptor splicing in induced pluripotent stem cell-derived neurons from patients with familial schizophrenia2021

    • Author(s)
      Yamamoto Kana、Kuriu Toshihiko、Takuma Kazuhiro、Ono Fumihito、Matsumoto Naomichi、Hashimoto Ryota、Hashimoto Hitoshi、Nakazawa Takanobu
    • Journal Title

      Translational Psychiatry

      Volume: 11 Issue: 1 Pages: 548-548

    • DOI

      10.1038/s41398-021-01676-1

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Tumor necrosis factor-α expression aberration of M1/M2 macrophages in adult high-functioning autism spectrum disorder.2021

    • Author(s)
      Yamauchi T, Makinodan M, Toritsuka M, Okumura K, Kayashima Y, Ishida R, Kishimoto N, Takahashi M, Komori T, Yamaguchi Y, Takada R, Yamamuro K, Kimoto S, Yasuda Y, Hashimoto R, Kishimoto T
    • Journal Title

      Autism Research

      Volume: 14 Issue: 11 Pages: 2330-2341

    • DOI

      10.1002/aur.2585

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Effects of copy number variations on brain structure and risk for psychiatric illness: Large‐scale studies from the ENIGMA working groups on CNVs2021

    • Author(s)
      Sonderby I, ... , for the ENIGMA-CNV Working Group (Kikuchi M (16 in 31 authors)) and ENIGMA 22q11.2 Deletion Syndrome Working Group.
    • Journal Title

      Human Brain Mapping

      Volume: NA Issue: 1 Pages: 300-328

    • DOI

      10.1002/hbm.25354

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] MacaquePose: a novel ‘in the wild’ macaque monkey pose dataset for markerless motion capture.2021

    • Author(s)
      Labuguen RT, Matsumoto J, Negrete SB, Nishimaru H, Nishijo H, Takada M, Go Y, Inoue K, Shibata T
    • Journal Title

      Front Behav Neurosci

      Volume: 14 Pages: 581154-581154

    • DOI

      10.3389/fnbeh.2020.581154

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Morphological features of large layer V pyramidal neurons in cortical motor-related areas of macaque monkeys: analysis of basal dendrites.2021

    • Author(s)
      Takata Y, Nakagawa H, Ninomiya T, Yamanaka H, Takada M
    • Journal Title

      Sci Rep

      Volume: 11 Issue: 1 Pages: 4171-4171

    • DOI

      10.1038/s41598-021-83680-5

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Effects of optogenetic suppression of cortical input on primate thalamic neuronal activity during goal-directed behavior.2021

    • Author(s)
      Suzuki T W, Inoue K, Takada M, Tanaka M
    • Journal Title

      eNeuro

      Volume: 8 Issue: 2 Pages: ENEURO.0511-20.2021

    • DOI

      10.1523/eneuro.0511-20.2021

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Subcortical encoding of agent-relevant associative signals for adaptive social behavior in the macaque2021

    • Author(s)
      Noritake A, Ninomiya T, Isoda M
    • Journal Title

      Neurosci Biobehav Rev

      Volume: 125 Pages: 78-87

    • DOI

      10.1016/j.neubiorev.2021.02.018

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Do eye movement abnormalities in schizophrenia cause Praecox-Gefuhl?2021

    • Author(s)
      Hashimoto R
    • Journal Title

      Psychiatry Clin Neurosci

      Volume: 75 Issue: 3 Pages: 79-80

    • DOI

      10.1111/pcn.13197

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Intranasal oxytocin administration ameliorates social behavioral deficits in a POGZWT/Q1038R mouse model of autism spectrum disorder2021

    • Author(s)
      Kitagawa Kohei、Matsumura Kensuke、Baba Masayuki、Kondo Momoka、Takemoto Tomoya、Nagayasu Kazuki、Ago Yukio、Seiriki Kaoru、Hayata-Takano Atsuko、Kasai Atsushi、Takuma Kazuhiro、Hashimoto Ryota、Hashimoto Hitoshi、Nakazawa Takanobu
    • Journal Title

      Molecular Brain

      Volume: 14 Issue: 1 Pages: 56-56

    • DOI

      10.1186/s13041-021-00769-8

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Impaired inhibition of return during free-viewing behaviour in patients with schizophrenia2021

    • Author(s)
      Okada K, Miura K, Fujimoto M, Morita K, Yoshida M, Yamamori H, Yasuda Y, Iwase M, Shinozaki T, Fujita I, Hashimoto R
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1 Pages: 3237-3237

    • DOI

      10.1038/s41598-021-82253-w

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Relationship between white matter microstructure and work hours2021

    • Author(s)
      Matsumoto Junya、Fukunaga Masaki、Miura Kenichiro、Nemoto Kiyotaka、Koshiyama Daisuke、Okada Naohiro、Morita Kentaro、Yamamori Hidenaga、Yasuda Yuka、Fujimoto Michiko、Hasegawa Naomi、Watanabe Yoshiyuki、Kasai Kiyoto、Hashimoto Ryota
    • Journal Title

      Neuroscience Letters

      Volume: 740 Pages: 135428-135428

    • DOI

      10.1016/j.neulet.2020.135428

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Tonic firing mode of midbrain dopamine neurons continuously tracks reward values changing moment-by-moment2021

    • Author(s)
      Wang Y, Toyoshima O, Kunimatsu J, Yamada H, Matsumoto M
    • Journal Title

      Elife

      Volume: 10

    • DOI

      10.7554/elife.63166

    • NAID

      120007190960

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Investigating DNA Methylation of <i>SHATI/NAT8L</i> Promoter Sites in Blood of Unmedicated Patients with Major Depressive Disorder2020

    • Author(s)
      Miyanishi Hajime、Uno Kyosuke、Iwata Mina、Kikuchi Yuu、Yamamori Hidenaga、Yasuda Yuka、Ohi Kazutaka、Hashimoto Ryota、Hattori Kotaro、Yoshida Sumiko、Goto Yu-ichi、Sumiyoshi Tomiki、Nitta Atsumi
    • Journal Title

      Biological and Pharmaceutical Bulletin

      Volume: 43 Issue: 7 Pages: 1067-1072

    • DOI

      10.1248/bpb.b19-01099

    • NAID

      130007867923

    • ISSN
      0918-6158, 1347-5215
    • Year and Date
      2020-07-01
    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Neuroimaging studies within Cognitive Genetics Collaborative Research Organization aiming to replicate and extend works of ENIGMA2020

    • Author(s)
      Koshiyama Daisuke、Miura Kenichiro、Nemoto Kiyotaka、Okada Naohiro、Matsumoto Junya、Fukunaga Masaki、Hashimoto Ryota
    • Journal Title

      Human Brain Mapping

      Volume: in press Issue: 1 Pages: 182-193

    • DOI

      10.1002/hbm.25040

    • NAID

      120007180728

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Optogenetic manipulation of a value-coding pathway from the primate caudate tail facilitates saccadic gaze shift.2020

    • Author(s)
      Amita H; Kim H; Inoue K; Takada M; Hikosaka O
    • Journal Title

      Nat Commun

      Volume: 11 Issue: 1 Pages: 1876-1876

    • DOI

      10.1038/s41467-020-15802-y

    • Related Report
      2020 Annual Research Report 2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Primate amygdalo-nigral pathway for boosting oculomotor action in motivating situations.2020

    • Author(s)
      Maeda K, Inoue K, Kunimatsu J, Takada M, Hikosaka O
    • Journal Title

      iScience

      Volume: 23 Issue: 6 Pages: 101194-101194

    • DOI

      10.1016/j.isci.2020.101194

    • NAID

      120007163351

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Olig2-Induced Semaphorin Expression Drives Corticospinal Axon Retraction After Spinal Cord Injury2020

    • Author(s)
      Ueno Masaki、Nakamura Yuka、Nakagawa Hiroshi、Niehaus Jesse K、Maezawa Mari、Gu Zirong、Kumanogoh Atsushi、Takebayashi Hirohide、Lu Qing Richard、Takada Masahiko、Yoshida Yutaka
    • Journal Title

      Cerebral Cortex

      Volume: 30 Issue: 11 Pages: 5702-5716

    • DOI

      10.1093/cercor/bhaa142

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] An Open Resource for Non-human Primate Optogenetics2020

    • Author(s)
      Tremblay Sebastien、Acker Leah、Afraz Arash、Albaugh Daniel L.、Amita Hidetoshi et al.
    • Journal Title

      Neuron

      Volume: 108 Issue: 6 Pages: 1075-1090

    • DOI

      10.1016/j.neuron.2020.09.027

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Representation of distinct reward variables for self and other in primate lateral hypothalamus.2020

    • Author(s)
      Noritake A, Ninomiya T, Isoda M.
    • Journal Title

      Proc Natl Acad Sci U S A.

      Volume: 117(10) Issue: 10 Pages: 5516-5524

    • DOI

      10.1073/pnas.1917156117

    • Related Report
      2020 Annual Research Report 2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] A causal role for frontal cortico-cortical coordination in social action monitoring2020

    • Author(s)
      Ninomiya T, Noritake A, Kinoshita K, Isoda M
    • Journal Title

      Nat Commun

      Volume: 11 Issue: 1 Pages: 5233-5233

    • DOI

      10.1038/s41467-020-19026-y

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Ethnicity-Dependent Effects of Schizophrenia Risk Variants of the OLIG2 Gene on OLIG2 Transcription and White Matter Integrity2020

    • Author(s)
      Komatsu H, Takeuchi H, Kikuchi Y, Ono C, Yu Z, Iizuka K, Takano Y, Kakuto Y, Funakoshi S, Ono T, Ito J, Kunii Y, Hino M, Nagaoka A, Iwasaki Y, Yamamori H, Yasuda Y, Fujimoto M, Azechi H, Kudo N, Hashimoto R, Yabe H, Yoshida M, Saito Y, Kakita A, Fuse N, Kawashima R, Taki Y, Tomita H
    • Journal Title

      Schizophrenia Bulletin

      Volume: - Issue: 6 Pages: 1619-1628

    • DOI

      10.1093/schbul/sbaa049

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Promoter Activity-Based Case-Control Association Study on SLC6A4 Highlighting Hypermethylation and Altered Amygdala Volume in Male Patients With Schizophrenia2020

    • Author(s)
      Ikegame T, Bundo M, Okada N, Murata Y, Koike S, Sugawara H, Saito T, Ikeda M, Owada K, Fukunaga M, Yamashita F, Koshiyama D, Natsubori T, Iwashiro N, Asai T, Yoshikawa A, Nishimura F, Kawamura Y, Ishigooka J, Kakiuchi C, Sasaki T, Abe O, Hashimoto R, Iwata N, Yamasue H, Kato T, Kasai K, Iwamoto K
    • Journal Title

      Schizophrenia Bulletin

      Volume: 46 Issue: 6 Pages: 1577-1586

    • DOI

      10.1093/schbul/sbaa075

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Polygenic risk scores for late smoking initiation associated with the risk of schizophrenia2020

    • Author(s)
      Ohi Kazutaka、Nishizawa Daisuke、Muto Yukimasa、Sugiyama Shunsuke、Hasegawa Junko、Soda Midori、Kitaichi Kiyoyuki、Hashimoto Ryota、Shioiri Toshiki、Ikeda Kazutaka
    • Journal Title

      npj Schizophrenia

      Volume: 6 Issue: 1 Pages: 36-36

    • DOI

      10.1038/s41537-020-00126-z

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Association between the superior longitudinal fasciculus and perceptual organization and working memory: A diffusion tensor imaging study2020

    • Author(s)
      Koshiyama Daisuke、Fukunaga Masaki、Okada Naohiro、Morita Kentaro、Nemoto Kiyotaka、Yamashita Fumio、Yamamori Hidenaga、Yasuda Yuka、Matsumoto Junya、Fujimoto Michiko、Kudo Noriko、Azechi Hirotsugu、Watanabe Yoshiyuki、Kasai Kiyoto、Hashimoto Ryota
    • Journal Title

      Neuroscience Letters

      Volume: 738 Pages: 135349-135349

    • DOI

      10.1016/j.neulet.2020.135349

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Increased Dendritic Orientation Dispersion in the Left Occipital Gyrus is Associated with Atypical Visual Processing in Adults with Autism Spectrum Disorder.2020

    • Author(s)
      Matsuoka K, Hashimoto R, Kishimoto T, et al.
    • Journal Title

      Cereb Cortex

      Volume: 30 Issue: 11 Pages: 5617-5625

    • DOI

      10.1093/cercor/bhaa121

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Associations of childhood experiences with event-related potentials in adults with autism spectrum disorder2020

    • Author(s)
      Okazaki Kosuke、Ota Toyosaku、Makinodan Manabu、Kishimoto Naoko、Yamamuro Kazuhiko、Ishida Rio、Takahashi Masato、Yasuda Yuka、Hashimoto Ryota、Iida Junzo、Kishimoto Toshifumi
    • Journal Title

      Scientific Reports

      Volume: 10 Issue: 1 Pages: 1-1

    • DOI

      10.1038/s41598-020-70409-z

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] ARHGAP10, which encodes Rho GTPase-activating protein 10, is a novel gene for schizophrenia risk2020

    • Author(s)
      Mariko Sekiguchi, Akiko Kodama,... Emiko Shishido,... Daisuke Mori, Norio Ozaki
    • Journal Title

      Translational psychiatry

      Volume: 10 Issue: 1 Pages: 1-15

    • DOI

      10.1038/s41398-020-00917-z

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Plasma levels of matrix metalloproteinase‐9 (MMP‐9) are associated with cognitive performance in patients with schizophrenia2020

    • Author(s)
      Kudo Noriko、Yamamori Hidenaga、Ishima Tamaki、Nemoto Kiyotaka、Yasuda Yuka、Fujimoto Michiko、Azechi Hirotsugu、Niitsu Tomihisa、Numata Shusuke、Ikeda Manabu、Iyo Masaomi、Ohmori Tetsuro、Fukunaga Masaki、Watanabe Yoshiyuki、Hashimoto Kenji、Hashimoto Ryota
    • Journal Title

      Neuropsychopharmacology Reports

      Volume: - Issue: 2 Pages: 150-156

    • DOI

      10.1002/npr2.12098

    • NAID

      120007027668

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Polygenetic risk scores for major psychiatric disorders among schizophrenia patients, their first-degree relatives, and healthy participants.2020

    • Author(s)
      Ohi K, Nishizawa D, Shimada T, Kataoka Y, Hasegawa J, Shioiri T, Kawasaki Y, Hashimoto R, Ikeda K
    • Journal Title

      Int J Neuropsychopharmacol

      Volume: 23 Issue: 3 Pages: 157-164

    • DOI

      10.1093/ijnp/pyz073

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Polygenic Architecture of Human Neuroanatomical Diversity2020

    • Author(s)
      Biton Anne, Kikuchi Masataka (13 of 25 authors), Toro Roberto
    • Journal Title

      Cerebral Cortex

      Volume: 30 Issue: 4 Pages: 2307-2320

    • DOI

      10.1093/cercor/bhz241

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Signal dynamics of midbrain dopamine neurons during economic decision-making in monkeys2020

    • Author(s)
      Yun M, Kawai T, Nejime M, Yamada H, Matsumoto M
    • Journal Title

      Science Advances

      Volume: 6 Issue: 27

    • DOI

      10.1126/sciadv.aba4962

    • NAID

      120007163349

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Delayed Prefrontal Hemodynamic Response Associated With Suicide Risk in Autism Spectrum Disorder2020

    • Author(s)
      Ota T, Iida J, Okazaki K, Ishida R, Takahashi M, Okamura K, Yamamuro K, Kishimoto N, Kimoto S, Yasuda Y, Hashimoto R, Makinodan M, Kishimoto T.
    • Journal Title

      Psychiatry Res

      Volume: 289 Pages: 112971-112971

    • DOI

      10.1016/j.psychres.2020.112971

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Eye movement characteristics in schizophrenia: A recent update with clinical implications.2020

    • Author(s)
      Morita K, Miura K, Kasai K, Hashimoto R.
    • Journal Title

      Neuropsychopharmacol Rep

      Volume: 40(1) Issue: 1 Pages: 2-9

    • DOI

      10.1002/npr2.12087

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Differentiation of schizophrenia using structural MRI with consideration of scanner differences: A real-world multi-site study.2020

    • Author(s)
      Nemoto K, Shimokawa T, Fukunaga M, Yamashita F, Tamura M, Yamamori H, Yasuda Y, Azechi H, Kudo N, Watanabe Y, Kido M, Takahashi T, Koike S, Okada N, Hirano Y, Onitsuka T, Yamasue H, Suzuki M, Kasai K, Hashimoto R, Arai T.
    • Journal Title

      Psychiatry Clin Neurosci

      Volume: 74(1) Issue: 1 Pages: 56-63

    • DOI

      10.1111/pcn.12934

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Pathogenic POGZ mutation causes impaired cortical development and reversible autism-like phenotypes.2020

    • Author(s)
      Matsumura K, (33名中略), Hashimoto R, (37名中35番目),Hashimoto H, Nakazawa T.
    • Journal Title

      Nat. Commun

      Volume: 11(1) Issue: 1 Pages: 859-859

    • DOI

      10.1038/s41467-020-14697-z

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Brain morphological and functional features in cognitive subgroups of Schizophrenia.2020

    • Author(s)
      Yasuda Y, Okada N, Nemoto K, Fukunaga M, Yamamori H, Ohi K, Koshiyama D, Kudo N, Shiino T, Morita S, Morita K, Azechi H, Fujimoto M, Miura K, Watanabe Y, Kasai K, Hashimoto R.
    • Journal Title

      Psychiatry Clin Neurosci

      Volume: 74(3) Issue: 3 Pages: 191-203

    • DOI

      10.1111/pcn.12963

    • NAID

      120007132757

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Comparison of eye movements in schizophrenia and autism spectrum disorder.2020

    • Author(s)
      Shiino T, Miura K, Fujimoto M, Kudo N, Yamamori H, Yasuda Y,Ikeda M, Hashimoto R.
    • Journal Title

      Neuropsychopharmacol Rep

      Volume: 40(1) Issue: 1 Pages: 92-95

    • DOI

      10.1002/npr2.12085

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The genetic architecture of the human cerebral cortex.2020

    • Author(s)
      Grasby KL, (297名中略) Hashimoto R〈299番目360 名中), (60名中略) Medland SE,
    • Journal Title

      Science

      Volume: 367(6484) Issue: 6484 Pages: 1340-1340

    • DOI

      10.1126/science.aay6690

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Dose response of the 16p11.2 distal copy number variant on intracranial volume and basal ganglia.2020

    • Author(s)
      Sonderby IE,  (50名中略) Hashimoto R(151名中52番目), (108名中略) Andreassen OA,
    • Journal Title

      Mol Psychiatry

      Volume: 25(3) Issue: 3 Pages: 584-602

    • DOI

      10.1038/s41380-018-0118-1

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Deschloroclozapine: a potent and selective chemogenetic actuator enables rapid neuronal and behavioral modulations in mice and monkeys2019

    • Author(s)
      Nagai Y, Miyakawa N, et al.
    • Journal Title

      bioRxiv

      Volume: - Pages: 1157-1167

    • DOI

      10.1101/854513

    • Related Report
      2020 Annual Research Report 2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] An overlapping pattern of cerebral cortical thinning is associated with both positive symptoms and aggression in schizophrenia via the ENIGMA consortium2019

    • Author(s)
      Wong Ting Yat、Radua Joaquim、Pomarol-Clotet Edith、Salvador Raymond、...、Hashimoto Ryota、Fukunaga Masaki、...、van Erp Theo G. M.、Gur Ruben C.、Nickl-Jockschat Thomas
    • Journal Title

      Psychological Medicine

      Volume: 16 Issue: 12 Pages: 1-12

    • DOI

      10.1017/s0033291719002149

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] The Self-Construal Scale: A Potential Tool for Predicting Subjective Well-Being of Individuals With Autism Spectrum Disorder2019

    • Author(s)
      Sachie Kaneko 1 2 3 , Takahiro A Kato 1 , Manabu Makinodan 4 , Takashi Komori 4 , Rio Ishida 4 , Naoko Kishimoto 4 , Masato Takahashi 4 , Yuka Yasuda 4 5 6 , Ryota Hashimoto 6 7 , Hidemi Iwasaka 3 , Ayumi Tanaka 8 , Yukiko Uchida 2 , Shigenobu Kanba 1 , Toshifumi Kishimoto 4
    • Journal Title

      Autism Res

      Volume: in press Issue: 6 Pages: 947-958

    • DOI

      10.1002/aur.2242

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] White matter microstructural alterations across four major psychiatric disorders: mega-analysis study in 2937 individuals2019

    • Author(s)
      Koshiyama Daisuke、(他38名18番目)Yamamoto Meeri
    • Journal Title

      Molecular Psychiatry

      Volume: 25 Issue: 4 Pages: 883-895

    • DOI

      10.1038/s41380-019-0553-7

    • NAID

      120006980539

    • Related Report
      2020 Annual Research Report 2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Oral splint ameliorates tic symptoms in patients with tourette syndrome2019

    • Author(s)
      Murakami Jumpei、Tachibana Yoshihisa、Akiyama Shigehisa、Kato Takafumi、Taniguchi Aya、Nakajima Yoshiaki、Shimoda Mao、Wake Hiroaki、Kano Yukiko、Takada Masahiko、Nambu Atsushi、Yoshida Atsushi
    • Journal Title

      Movement Disorders

      Volume: 34 Issue: 10 Pages: 1577-1578

    • DOI

      10.1002/mds.27819

    • NAID

      120006799316

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Optogenetic recruitment of spinal reflex pathways from large‐diameter primary afferents in non‐transgenic rats transduced with AAV9/Channelrhodopsin 22019

    • Author(s)
      Kubota Shinji、Sidikejiang Wupuer、Kudo Moeko、Inoue Ken‐ichi、Umeda Tatsuya、Takada Masahiko、Seki Kazuhiko
    • Journal Title

      The Journal of Physiology

      Volume: 597 Issue: 19 Pages: 5025-5040

    • DOI

      10.1113/jp278292

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Layer specificity of inputs from supplementary motor area and dorsal premotor cortex to primary motor cortex in macaque monkeys.2019

    • Author(s)
      Ninomiya T; Inoue K; Hoshi E; Takada M
    • Journal Title

      Sci Rep

      Volume: 9 Issue: 1 Pages: 18230-18230

    • DOI

      10.1038/s41598-019-54220-z

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Store-Operated Calcium Channels Are Involved in Spontaneous Slow Calcium Oscillations in Striatal Neurons2019

    • Author(s)
      Kikuta Satomi、Iguchi Yoshio、Kakizaki Toshikazu、Kobayashi Kazuto、Yanagawa Yuchio、Takada Masahiko、Osanai Makoto
    • Journal Title

      Frontiers in Cellular Neuroscience

      Volume: 13 Pages: 1-9

    • DOI

      10.3389/fncel.2019.00547

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Current Perspective: Modeling of psychiatric disorders using induced pluripotent stem cell-related technologies.2019

    • Author(s)
      Nakazawa T, Hashimoto R, Takuma K, Hashimoto H.
    • Journal Title

      J Pharmacol Sci,

      Volume: 140(4) Issue: 4 Pages: 321-324

    • DOI

      10.1016/j.jphs.2019.06.002

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Eye movement abnormalities and their association with cognitive impairments in schizophrenia.2019

    • Author(s)
      Morita K, Miura K, Fujimoto M, Yamamori H, Yasuda Y, Kudo N, Azechi H, Okada N, Koshiyama D, Ikeda M, Kasai K, Hashimoto R.
    • Journal Title

      Schizophr Res

      Volume: 209 Pages: 255-262

    • DOI

      10.1016/j.schres.2018.12.051

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Eye movement characteristics of schizophrenia and their association with cortical thickness.2019

    • Author(s)
      Morita K, Hashimoto R, et al.
    • Journal Title

      Psychiat Clin Neurosci

      Volume: 73 Issue: 8 Pages: 508-509

    • DOI

      10.1111/pcn.12865

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] A 1.5-year longitudinal study of social activity in patients with schizophrenia.2019

    • Author(s)
      Ohi K, Sumiyoshi C, Fujino H, Yasuda Y, Yamamori H, Fujimoto M, Sumiyoshi T, Hashimoto R
    • Journal Title

      Front Psychiat

      Volume: 10 Pages: 567-567

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Improvement of psychiatrists’ clinical knowledge of the treatment guidelines for schizophrenia and major depressive disorders using the “Effectiveness of Guidelines for Dissemination and Education in psychiatric treatment (EGUIDE) ” project: a nationwide dissemination, education and evaluation study.2019

    • Author(s)
      Takaesu Y, Watanabe K, (44名中略) Inada K, Hashimoto R.
    • Journal Title

      Psychiatry Clin Neurosci

      Volume: 73(10) Issue: 10 Pages: 642-648

    • DOI

      10.1111/pcn.12911

    • NAID

      120007029981

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Autism-associated protein kinase D2 regulates embryonic cortical neuron development.2019

    • Author(s)
      Matsumura K, Baba M, Nagayasu K, Yamamoto K, Kondo M, Kitagawa K, Takemoto T, Seiriki K, Kasai A, Ago Y, Hayata-Takano A, Shintani N, Kuriu T, Iguchi T, Sato M, Takuma K, Hashimoto R, Hashimoto H.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 519(3) Issue: 3 Pages: 626-632

    • DOI

      10.1016/j.bbrc.2019.09.048

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Psychiatric-disorder-related behavioral phenotypes and cortical hyperactivity in a mouse model of 3q29 deletion syndrome.2019

    • Author(s)
      Baba M, Yokoyama K, Seiriki K, Naka Y, Matsumura K, Kondo M, Yamamoto K, Hayashida M, Kasai A, Ago Y, Nagayasu K, Hayata-Takano A, Takahashi A, Yamaguchi S, Mori D, Ozaki N, Yamamoto T, Takuma K, Hashimoto R, Hashimoto H, Nakazawa T.
    • Journal Title

      Neuropsychopharmacology

      Volume: 44(12) Issue: 12 Pages: 2125-2135

    • DOI

      10.1038/s41386-019-0441-5

    • NAID

      130007811380

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Preferential representation of past outcome information and future choice behavior by putative inhibitory interneurons rather than putative pyramidal neurons in the primate dorsal anterior cingulate cortex2018

    • Author(s)
      Takashi Kawai, Hiroshi Yamada, Nobuya Sato, Masahiko Takada, Masayuki Matsumoto
    • Journal Title

      Cerebral Cortex

      Volume: 印刷中 Issue: 6 Pages: 2339-2352

    • DOI

      10.1093/cercor/bhy103

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Genome-Wide Association Study Detected Novel Susceptibility Genes for Schizophrenia and Shared Trans-Populations/Diseases Genetic Effect2018

    • Author(s)
      Ikeda M,Takahashi A,Kamatani Y,Momozawa Y,Saito T,Kondo K,Shimasaki A,Kawase K,Sakusabe T,Iwayama Y,Toyota T,Wakuda T,Kikuchi M,Kanahara N,Yamamori H,Yasuda Y,Watanabe Y,Hoya S,Aleksic B,Kushima I,Arai H,Takaki M,Hattori K,Kunugi H,Okahisa Y,Ohnuma T,Ozaki N,Someya T,Hashimoto R,Yoshikawa T,Kubo M,Iwata N
    • Journal Title

      Schizophrenia Bulletin

      Volume: 印刷中 Issue: 4 Pages: 824-834

    • DOI

      10.1093/schbul/sby140

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Presentation] マイクロバブルと経頭蓋集束超音波照射を用いた一過性血液脳関門開放による霊長類脳への非侵襲的外来遺伝子導入2024

    • Author(s)
      高田 昌彦
    • Organizer
      第129回日本解剖学会総会・全国学術集会
    • Related Report
      2023 Annual Research Report
  • [Presentation] A fluorescent dopamine sensor reveals distinct signals on reward prediction error and expected reward value in the primate putamen and caudate nucleus2023

    • Author(s)
      Yan G, Amita H, Nonomura S, Inoue K, Takada M
    • Organizer
      XIVth Meeting for International Basal Ganglia Society
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Medial prefrontal cortex neuron negatively controls action switch based on diminishing reward in rats2023

    • Author(s)
      Nonomura S, Takayasu T, Kaneko T, Amita H, Inoue K, Takada M
    • Organizer
      XIVth Meeting for International Basal Ganglia Society
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 非ヒト霊長類を用いたAAVベクター研究の新展開2023

    • Author(s)
      高田 昌彦
    • Organizer
      第66回日本神経化学会大会
    • Related Report
      2023 Annual Research Report
  • [Presentation] マウス CD25特異的組換え体イムノトキシンを利用したコモンマーモセット脳内神経細胞種の選択的ターゲティング2023

    • Author(s)
      小林 とも子、加藤 成樹、菅原 正晃、小澤 龍彦、井上 謙一、高田 昌彦、恩田 正徳、小林 和人
    • Organizer
      第46回日本神経科学大会
    • Related Report
      2023 Annual Research Report
  • [Presentation] Integration of Reward Expectation and Action Selection in the Nigrostriatal System2023

    • Author(s)
      Rios A, Nonomura S, Kato S, Yoshida J, Matsushida N, Nambu A, Takada M, Hira R, Kobayashi K, Sakai Y, Kimura M, Isomura K
    • Organizer
      第46回日本神経科学大会
    • Related Report
      2023 Annual Research Report
  • [Presentation] A versatile tool for automated quantification of natural/social behaviors in the common marmosets2023

    • Author(s)
      Zhao X, Kaneko T, Matsumoto J, Lu W, Ueno L, Oishi T, Ikenaka K, Baba K, Nishijo H, Mochizuki H, Inoue K, Takada M
    • Organizer
      第46回日本神経科学大会
    • Related Report
      2023 Annual Research Report
  • [Presentation] Behavioral adjustment to others’ internal states in the common marmosets under a food competition task2023

    • Author(s)
      Lu W, Kaneko T, Matsumoto J, Zhao X, Ueno L, Oishi T, Inoue K, Takada M
    • Organizer
      第46回日本神経科学大会
    • Related Report
      2023 Annual Research Report
  • [Presentation] 概日時計によって制御される哺乳類の記憶・学習2023

    • Author(s)
      清水 貴美子、井上 謙一、小林 洋大、大石 高生、高田 昌彦、今井 啓雄、深田 吉孝
    • Organizer
      第46回日本神経科学大会
    • Related Report
      2023 Annual Research Report
  • [Presentation] 報酬の漸減に基づいた行動選択に関わる内側前頭前皮質からの情報伝達2023

    • Author(s)
      野々村 聡、兼子 峰明、網田 英敏、井上 謙一、高田 昌彦
    • Organizer
      第46回日本神経科学大会
    • Related Report
      2023 Annual Research Report
  • [Presentation] マカクザルの前部帯状皮質から中脳中心灰白質への局在投射2023

    • Author(s)
      曽我 ゆふき、吉野 倫太郎、木村 慧、大原 慎也、中村 晋也、井上 謙一、高田 昌彦、筒井 健一郎
    • Organizer
      第46回日本神経科学大会
    • Related Report
      2023 Annual Research Report
  • [Presentation] Selective silencing of the ventral striatum-ventral pallidum pathway enhances approach choices and motivational states under approach-avoidance conflict in nonhuman primates2023

    • Author(s)
      Oh J, Amemori S, Inoue K, Kimura K, Takada M, Amemori K
    • Organizer
      Neuroscience 2023
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Behavioral adjustment in response to others’ internal state in common marmosets: AI based quantification using neural networks that predict the internal state solely from actions2023

    • Author(s)
      Lu W, Kaneko T, Matsumoto J, Zhao X, Ueno L, Oishi T, Inoue K, Takada M
    • Organizer
      Neuroscience 2023
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Neural representations of medial prefrontal cortex neurons projecting to the striatum for diminishing reward-based action switch2023

    • Author(s)
      Nonomura S, Kaneko T, Amita H, Inoue K, Takada M
    • Organizer
      Neuroscience 2023
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Parvalbumin-positive neuron-selective gene transduction into the monkey striatum2023

    • Author(s)
      Zheng A, Kimura K, Nagai Y, Fujiwara M, Nakano M, Nagayasu K, Inoue K, Takada M
    • Organizer
      Neuroscience 2023
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Characterizing the functional role of Interhemispheric Connections in value decisions using optical tools2023

    • Author(s)
      Gopal A, Yu X, Mejias-Aponte C, Inoue K, Takada M, Hikosaka O
    • Organizer
      Neuroscience 2023
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Dopamine signals transmitted to different subregions of the primate striatum during economic decision-making2023

    • Author(s)
      Duo Z, Wang Y, Nejime M, Kunimatsu J, Amita H, Inoue K, Takada M, Yamada H, Matsumoto M
    • Organizer
      Neuroscience 2023
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research
  • [Presentation] An AI system for quantification of common marmoset natural behaviors using markerless 3D pose estimation2023

    • Author(s)
      Zhao X, Kaneko T, Matsumoto J, Lu W, Ueno L, Oishi T, Ikenaka K, Baba K, Nishijo H, Mochizuki H, Inoue K, Takada M
    • Organizer
      Neuroscience 2023
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Optogenetic Tagging of the Oculomotor Pathway in Non-Human Primates2023

    • Author(s)
      Yu X, Gopal A, Inoue K, Takada M, Hikosaka O
    • Organizer
      Neuroscience 2023
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Distinct roles of two frontal areas in action prediction2023

    • Author(s)
      Ninomiya T, Isoda M
    • Organizer
      Neuroscience 2023
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Cortical structural mega-analysis across four major psychiatric disorders in 5432 individuals.2023

    • Author(s)
      Matsumoto J, Hashimoto R. et al.
    • Organizer
      第119回日本精神神経学会学術総会
    • Related Report
      2023 Annual Research Report
  • [Presentation] 児童思春期発症のうつ病の多施設大規模データによる大脳皮質構造解2023

    • Author(s)
      松本純弥、橋本亮太 他
    • Organizer
      第45回日本生物学的精神医学会年会
    • Related Report
      2023 Annual Research Report
  • [Presentation] Cognitive signals in the cerebellar dentate nucleus contribute to the associative learning.2023

    • Author(s)
      Akiyama Y, Yamada H, Matsumoto M, Kunimatsu J
    • Organizer
      Neuroscience 2023
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research
  • [Presentation] A versatile tool for the stable manipulation and imaging of neural circuit activity in primate brain2023

    • Author(s)
      Kimura K, Nagai Y, Hatanaka G, Fang Y, Tanabe S, Zheng A, Fujiwara M, Nakano M, Hori Y, Takeuchi R, Inagaki M, Minamimoto T, Fujita I, Inoue K, Takada M
    • Organizer
      第4回 「サル脳新技術研究会」
    • Related Report
      2022 Annual Research Report
  • [Presentation] A versatile tool for automated quantification of natural behavior in marmosets2023

    • Author(s)
      Kaneko T, Matsumoto J, Lu W, Zhao X, Ueno L, Nishijo H, Mochizuki H, Inoue K, Takada M
    • Organizer
      生理研研究会「行動制御の脳内基盤理解へのマルチディシプリナリーアプローチ」、国際研究集会「大脳皮質ー大脳基底核神経回路の機能とその破綻がもたらす機能障害」
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research
  • [Presentation] マカクザル社会的行動モニタリングの神経基盤2023

    • Author(s)
      二宮太平
    • Organizer
      第100回日本生理学会
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] ヒト染色体3q29領域欠失を導入した自閉スペクトラム症モデルマウスの社会行動異常はオキシトシンの投与により回復する2023

    • Author(s)
      竹本智哉、馬場優志、北川航平、永安一樹、勢力薫、早田敦子、笠井淳司、吾郷由希夫、 田熊?敞、橋本亮太、橋本均、中澤敬信
    • Organizer
      日本薬学会第143年会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 環境エンリッチメントによる3q29領域欠失導入マウスの精神疾患様行動の回復2023

    • Author(s)
      秋本祐弥、馬場優志、福島穂高、三浦大樹、橋本均、橋本亮太、中澤敬信
    • Organizer
      日本薬学会第143年会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 患者iPS細胞由来分化神経系細胞を用いた2p16.3領域欠失変異の分子病態解析2023

    • Author(s)
      高田智弘、河野翔太郎、鮎澤有希子、三浦大樹、福島穂高、橋本亮太、橋本均、中澤敬信
    • Organizer
      日本薬学会第143年会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 患者iPS細胞由来分化神経系細胞を用いた3q29領域欠失変異の分子病態解析2023

    • Author(s)
      河野翔太郎、高田智弘、鮎澤有希子、三浦大樹、福島穂高、橋本亮太、橋本均、中澤敬信
    • Organizer
      日本薬学会第143年会
    • Related Report
      2022 Annual Research Report
  • [Presentation] ウィルストレーシングによるマカクザル内側前頭皮質から扁桃体への投射様式2022

    • Author(s)
      吉野 倫太郎, 木村 慧, 田辺 創思, Andi Zheng, 中村 晋也, 大原 慎也, 井上 謙一, 高田 昌彦, 筒井 健一郎
    • Organizer
      第45回日本神経科学大会
    • Related Report
      2022 Annual Research Report
  • [Presentation] サル脳内DREADD発現と効果の長期的評価2022

    • Author(s)
      永井 裕司, 堀 由紀子, 井上 謙一, 小山 佳, 宮川 尚久, 平林 敏行, 三村 喬生, 須原 哲也, 高田 昌彦, 樋口 真人, 南本 敬史
    • Organizer
      第45回日本神経科学大会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 霊長類脳への高効率な導入遺伝子発現と神経細胞特異的な感染を実現するモザイクAAVベクターの開発2022

    • Author(s)
      木村 慧, 永井 裕司, 畑中 岳, Yang Fang, 田辺 創思, Andi Zheng, 藤原 真紀, 中野 真由子, 堀 由紀子, 竹内 遼介, 稲垣 未来男, 南本 敬史, 藤田 一郎, 井上 謙一, 高田 昌彦
    • Organizer
      第45回日本神経科学大会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 群飼ケージ内で自由行動する複数サル個体の3Dマーカーレスモーションキャプチャー2022

    • Author(s)
      松本 惇平, 兼子 峰明, 木村 慧, Negrete Salvador, 橋本-須田 直子, 兼子 明久, 森本 真弓, 角谷 絵里, 西丸 広史, 瀬戸川 剛, 郷 康広, 柴田 智広, 西条 寿夫, 高田 昌彦, 井上 謙一
    • Organizer
      第45回日本神経科学大会
    • Related Report
      2022 Annual Research Report
  • [Presentation] Fluorescent sensor reveals dopamine dynamics in the primate striatum2022

    • Author(s)
      Yan G, 網田 英敏, 野々村 聡, 井上 謙一, 高田 昌彦
    • Organizer
      第45回日本神経科学大会
    • Related Report
      2022 Annual Research Report
  • [Presentation] Medial prefrontal cortex neuron activity in relation to diminishing reward-based action selection in rats2022

    • Author(s)
      Nonomura S, Takayasu T, Kaneko T, Amita H, Inoue K, Takada M
    • Organizer
      Neuroscience 2022
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research
  • [Presentation] A cortico-subcortical circuit plays a causal role in social reward monitoring and valuation2022

    • Author(s)
      Noritake A, Ninomiya T, Kobayashi K, Isoda M
    • Organizer
      Neuroscience 2022
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research
  • [Presentation] サル上側頭溝中間部における自己と他者の動作情報表現2022

    • Author(s)
      二宮太平、則武厚、磯田昌岐
    • Organizer
      第45回日本神経科学大会
    • Related Report
      2022 Annual Research Report
  • [Presentation] Learning dependent activity in the lateral cerebellum during reinforcement learning2022

    • Author(s)
      Akiyama Y, Yamada H, Matsumoto M, Kunimatsu J
    • Organizer
      The 45th Annual Meeting of the Japanese Neuroscience Society
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Role of the lateral cerebellum in the visuo-motor association learning2022

    • Author(s)
      Akiyama Y, Yamada H, Matsumoto M, Kunimatsu J
    • Organizer
      第100回日本生理学会
    • Related Report
      2022 Annual Research Report
  • [Presentation] アデノ随伴ウイルスベクターを用いたマーモセット全脳への効率の良い遺伝子導入法の開発2022

    • Author(s)
      吉田哲, 井上謙一, 兼子峰明, 高田昌彦, 岡野栄之
    • Organizer
      第11回日本マーモセット研究会
    • Related Report
      2021 Annual Research Report
  • [Presentation] MacaquePose: A Novel "In the Wild" Macaque Monkey Pose Dataset for Markerless Motion Capture2021

    • Author(s)
      Labuguen R; Matsumoto J; Negrete SB; Nishimaru H; Nishijo H; Takada M; Go Y; Inoue KI; Shibata T
    • Organizer
      Computer Vision and Pattern Recognition (CVPR) 2021; CV4Animals: Computer Vision for Animal Behavior Tracking and Modeling
    • Related Report
      2021 Annual Research Report
  • [Presentation] 経済学的意思決定に関わるサル報酬系神経活動ダイナミクス2021

    • Author(s)
      禰占 雅史,惲 夢曦,川合 隆嗣,山田 洋,井上 謙一,高田 昌彦,松本 正幸
    • Organizer
      第44回日本神経科学大会
    • Related Report
      2021 Annual Research Report
  • [Presentation] 改変AAVベクターを用いた非ヒト霊長類新生仔への全脳的遺伝子導入2021

    • Author(s)
      井上 謙一,木村 慧,吉田 哲,田辺 創思,藤原 真紀,上野 瑠惟,高田 裕生,兼子 峰明,篠本 有里,中野 真由子,田中 江美子,角谷 絵里,岡野 栄之,高田 昌彦
    • Organizer
      第44回日本神経科学大会
    • Related Report
      2021 Annual Research Report
  • [Presentation] 霊長類線条体へのパルブアルブミン陽性ニューロン選択的遺伝子導入2021

    • Author(s)
      Andi Zheng,木村 慧,永井 佑茉,藤原 真紀,中野 真由子,永安 一樹,井上 謙一,高田 昌彦
    • Organizer
      第44回日本神経科学大会
    • Related Report
      2021 Annual Research Report
  • [Presentation] 化学遺伝学的手法を用いた霊長類側坐核の活動低下は接近回避葛藤タスク開始時の意欲を低下させる2021

    • Author(s)
      オ ジョンミン,雨森 智子,井上 謙一,木村 慧,高田 昌彦,雨森 賢一
    • Organizer
      第44回日本神経科学大会
    • Related Report
      2021 Annual Research Report
  • [Presentation] 精神神経疾患の霊長類モデル確立に向けたマカクザルのマーカーレスモーションキャプチャー用大規模教師データセットの作成とその応用2021

    • Author(s)
      松本 惇平,ラブグエン ローリン,兼子 峰明,ブランコ サルバトール,ジア グオ,西丸 広史,西条 寿夫,高田 昌彦,郷 康広,井上 謙一,柴田 智広
    • Organizer
      第44回日本神経科学大会
    • Related Report
      2021 Annual Research Report
  • [Presentation] 課題遂行中のサル第一次視覚野からの微小内視鏡カルシウムイメージング2021

    • Author(s)
      小口 峰樹, Jiang Jiasen, 吉岡 敏秀, 田中 康裕, 井上 謙一, 髙田 昌彦,菊水 健史,野元 謙作,坂上 雅道
    • Organizer
      第44回日本神経科学大会
    • Related Report
      2021 Annual Research Report
  • [Presentation] 化学遺伝学によるてんかん制御~薬剤モデルマカクザル研究2021

    • Author(s)
      宮川 尚久; 永井 裕司; 川嵜 圭祐; 堀 由紀子,小山 佳,折原 あすみ,松尾 健,鈴木 隆文,井上 謙一,高田 昌彦,須原 哲也,樋口 真人,南本 敬史
    • Organizer
      第44回日本神経科学大会
    • Related Report
      2021 Annual Research Report
  • [Presentation] Pathway-selective silencing of ventral striatum neurons projecting to the ventral pallidum elevates motivational states under approach-avoidance conflict in nonhuman primates2021

    • Author(s)
      Oh J; Amemori S; Inoue K; Kimura K; Takada M; Amemori K
    • Organizer
      Neuroscience 2021
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Chemogenetic suppression of pharmacologically induced frontal lobe epilepsy in a macaque monkey2021

    • Author(s)
      Miyakawa N; Nagai Y; Kawasaki K; Hori Y; Oyama K; Orihara A; Matsuo T; Suzuki T; Inoue K; Takada M; Suhara T; Higuchi M; Minamimoto T
    • Organizer
      75th Annual Meeting of the American Epilepsy Society
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Frontal cortico-cortical coordination and its causal role in social action monitoring2021

    • Author(s)
      Ninomiya T
    • Organizer
      第44回日本神経科学大会
    • Related Report
      2021 Annual Research Report
  • [Presentation] Neurons in the macaque amygdala encode face animacy and self-relevant gaze shift2021

    • Author(s)
      Arai K, Isoda M, Ninomiya T
    • Organizer
      Neuroscience 2021
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Combinations of cognitive function and eye movement tests are effective in distinguishing schizophrenia cases from healthy controls2021

    • Author(s)
      Miura K, Matsumoto J, Hasegawa N, Fujimoto M, Yamamori H, Yasuda Y, Hashimoto R
    • Organizer
      7th Congress of AsCNP 2021
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Cortical structural mega-analysis across four major psychiatric disorders in 5432 individuals2021

    • Author(s)
      Matsumoto J, Hashimoto R, et al.
    • Organizer
      7th Congress of AsCNP 2021
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Cross-diagnostic Comparisons of Intellectual Ability and Work Outcome in Patients with Mental Disorders: A Multi-center Study2021

    • Author(s)
      Sumiyoshi C, Ohi K, Fujino H, Yamamori H, Fujimoto M, Yasuda Y, Uno Y, Takahashi J, Morita K, Katsuki A, Yamamoto M, Okahisa Y, Sata A, Katsumoto E, Koeda M, Hirano Y, Nakataki1 M, Hashimoto N, Makinodan M, Takahashi T. Nemoto K, Kishimoto T, Suzuki M, Sumiyoshi T, Hashimoto R
    • Organizer
      2021 Congress of the Schizophrenia International Research Society
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 総合オーガナイザー、基礎神経科学と臨床精神医学が融合したブレークスルー研究の育て方(新学術領域研究[マルチスケール脳])2021

    • Author(s)
      橋本亮太
    • Organizer
      「次世代脳」プロジェクト第5回冬のシンポジウム2021
    • Related Report
      2021 Annual Research Report
  • [Presentation] データ駆動型解析による精神疾患のバイオタイプとは?2021

    • Author(s)
      橋本亮太、松本純弥、長谷川尚美、三浦健一郎
    • Organizer
      第117回日本精神神経学会学術総会
    • Related Report
      2021 Annual Research Report
    • Invited
  • [Presentation] 精神科領域における多施設共同研究の実際と研究倫理2021

    • Author(s)
      橋本亮太
    • Organizer
      第117回日本精神神経学会学術総会
    • Related Report
      2021 Annual Research Report
    • Invited
  • [Presentation] 治療抵抗性統合失調症へのクロザピン治療とは2021

    • Author(s)
      橋本亮太
    • Organizer
      第10回日本精神科医学会学術大会
    • Related Report
      2021 Annual Research Report
    • Invited
  • [Presentation] 座長、基礎-臨床連携シンポジウム:当事者・ご家族の想いを適える精神医学研究2021

    • Author(s)
      橋本亮太
    • Organizer
      第44回日本神経科学大会
    • Related Report
      2021 Annual Research Report
    • Invited
  • [Presentation] 統合失調症のバイオタイプ研究2021

    • Author(s)
      橋本亮太、松本純弥、長谷川尚美、三浦健一郎
    • Organizer
      第43回日本生物学的精神医学会・第51回日本神経精神薬理学会 合同年会
    • Related Report
      2021 Annual Research Report
    • Invited
  • [Presentation] The neural mechanism of the encoding of the familiar face in the primate striatum tail2021

    • Author(s)
      Kunimatsu Jun
    • Organizer
      The 50th Annual Meeting of the Society for Neuroscience
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 親しい人物の顔を素早く見つける神経メカニズム2021

    • Author(s)
      國松 淳
    • Organizer
      第15回Motor control研究会
    • Related Report
      2021 Annual Research Report
  • [Presentation] Polygenetic Risk Scores for Major Psychiatric Disorders among Schizophrenia Patients, Their First-Degree Relatives and Healthy Subjects.2021

    • Author(s)
      Ohi K, Nishizawa D, Shimada T, Kataoka Y, Hasegawa J, Shioiri T, Kawasaki Y, Hashimoto R, Ikeda K.
    • Organizer
      CINP(The International College of Neuropsychopharmacology (CINP)) 2021
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 人工知能技術を活用した精神疾患の層別化―病態の理解と新たな診断体系の構築に向けて―2021

    • Author(s)
      三浦健一郎、松本純弥、長谷川尚美、藤本美智子、山森英長、安田由華、橋本亮太
    • Organizer
      NCNP令和2年度精神保健研究所研究報告会
    • Related Report
      2020 Annual Research Report
  • [Presentation] 精神・神経・筋難病の克服を目指した研究開発2021

    • Author(s)
      橋本亮太、青木吉嗣
    • Organizer
      第5回国立研究開発法人イノベーション戦略会議
    • Related Report
      2020 Annual Research Report
  • [Presentation] 扁桃体が腹側視覚皮質における社会・情動性の視覚情報表現に果たす役割 ~化学遺伝学神経操作によるアプローチ2020

    • Author(s)
      宮川 尚久,永井 裕司,堀 由紀子,松尾 健,鈴木 隆文,井上 謙一,小山 桂,平林 敏行,高田 昌彦,須原 哲也,樋口 真人,川嵜 佳祐,南本 敬史
    • Organizer
      第43回日本神経科学大会
    • Related Report
      2020 Annual Research Report
  • [Presentation] マカクザル内側前頭皮質の側坐核及び扁桃体への投射様式の違いによる領域区分2020

    • Author(s)
      吉野 倫太郎, 木村 慧, 田辺 創思, 大原 慎也, 中村 晋也, 井上 謙一, 高田 昌彦
    • Organizer
      第43回日本神経科学大会
    • Related Report
      2020 Annual Research Report
  • [Presentation] DREADDを用いた経路選択的阻害法による、サル前頭前野と視床MD核及び線条体を結ぶ神経経路のワーキングメモリにおける役割の解明2020

    • Author(s)
      小山 佳, 堀 由紀子, 永井 裕司, 宮川 尚久, 三村 喬生, 平林 敏行, 井上 謙一, 高田 昌彦, 樋口 真人, 南本 敬史
    • Organizer
      第43回日本神経科学大会
    • Related Report
      2020 Annual Research Report
  • [Presentation] マカク一次視覚野における微小内視鏡を用いたカルシウムイメージング2020

    • Author(s)
      小口-田中 峰樹, Jiang Jiasen, 吉岡 敏秀, 田中 康裕, 井上 謙一, 高田 昌彦, 菊水 健史, 野元 謙作, 坂上 雅道
    • Organizer
      第43回日本神経科学大会
    • Related Report
      2020 Annual Research Report
  • [Presentation] 改変AAVベクターを用いた新生児霊長類への全脳的遺伝子導入2020

    • Author(s)
      井上 謙一,田辺 創思, 吉田 哲, 藤原 真紀, 木村 慧, 上野 瑠惟, 高田 裕生, 木村 活生, 兼子 峰明, 篠本 有里, 中野 真由子, 田中 江美子, 今度 ゆりこ, 角谷 絵里, 岡野 栄之, 高田 昌彦
    • Organizer
      第43回日本神経科学大会
    • Related Report
      2020 Annual Research Report
  • [Presentation] マカカ属サルにおける上丘から扁桃体への多シナプス性経路2020

    • Author(s)
      稲垣 未来男, 井上 謙一, 田辺 創思, 木村 慧, 高田 昌彦, 藤田 一郎
    • Organizer
      第43回日本神経科学大会
    • Related Report
      2020 Annual Research Report
  • [Presentation] 価値にもとづく眼球運動を制御する霊長類大脳基底核回路2020

    • Author(s)
      網田 英敏, Hyoung F Kim, 井上 謙一,高田 昌彦, 彦坂 興秀
    • Organizer
      第43回日本神経科学大会
    • Related Report
      2020 Annual Research Report
  • [Presentation] Partnering International Consortium:COCORO,2020

    • Author(s)
      Hashimoto R, Matsumoto J, Hasegawa N, Miura K.
    • Organizer
      The ENIGMA Consortium All-Hands Virtual Meeting 2020
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] EGUIDEプロジェクトメンバーズ、EGUIDEプロジェクトによる退院時処方への効果~クロザピンと医療の質(Quality Indicator)の関係に着目して~2020

    • Author(s)
      長谷川尚美、松本純弥、三浦健一郎、橋本亮太
    • Organizer
      NCNP令和元年度精神保健研究所研究報告会
    • Related Report
      2020 Annual Research Report
  • [Presentation] 精神疾患の多施設共同研究~病態解明から治療法の社会実装まで~2020

    • Author(s)
      橋本亮太
    • Organizer
      Mist seminer in GIFU
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] 3q29領域欠失変異を有する精神疾患患者のiPS神経細胞の機能解析2020

    • Author(s)
      近藤百香、栗生俊彦、馬場優志、北川航平、竹本智哉、永安一樹、山森英長、安田由華、藤本美智子、田熊一敞、小野富三人、橋本亮太、橋本均、中澤敬信
    • Organizer
      第138回日本薬理学会近畿部会
    • Related Report
      2020 Annual Research Report
  • [Presentation] ヒト染色体3q29欠失モデルマウスを用いた精神疾患の分子病態研究2020

    • Author(s)
      馬場優志、勢力薫,、近藤百香、北川航平、竹本智哉、笠井淳司、吾郷由希夫、 永安一樹、森大輔、尾崎紀夫、山本雅、田熊一敞、橋本亮太、橋本均、中澤敬信
    • Organizer
      第138回日本薬理学会近畿部会
    • Related Report
      2020 Annual Research Report
  • [Presentation] 精神疾患の脳科学:トランスレーショナルアプローチ2020

    • Author(s)
      橋本亮太、長谷川尚美、松本純弥、三浦健一郎
    • Organizer
      東京農業大学農学研究科大学院講義
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] 臨床研究者の立場から2020

    • Author(s)
      橋本亮太
    • Organizer
      第116回日本精神神経学会学術総会
    • Related Report
      2020 Annual Research Report
  • [Presentation] 統合失調症患者、非罹患近親者、健常者間における各精神疾患のポリジェニックリスクスコア2020

    • Author(s)
      大井一高、西澤大輔、嶋田貴充、片岡譲、長谷川準子、塩入俊樹、川﨑康弘、橋本亮太、池田和隆
    • Organizer
      第116回日本精神神経学会学術総会
    • Related Report
      2020 Annual Research Report
  • [Presentation] 大脳白質の軸索の髄鞘化、大脳白質の成熟と、認知機能・社会機能の指標である労働時間との関連2020

    • Author(s)
      松本純弥、福永雅喜、根本清貴、越山大輔、三浦健一郎、岡田直大、森田健太郎、山森英長、安田由華、藤本美智子、工藤紀子、笠井清登、渡邉嘉之、橋本亮太
    • Organizer
      第116回日本精神神経学会学術総会
    • Related Report
      2020 Annual Research Report
  • [Presentation] 統合失調症におけるバイオマーカーとしての眼球運動スコアの臨床的意義2020

    • Author(s)
      藤本美智子、三浦健一郎、森田健太郎、工藤紀子、畦地裕統、山森英長、安田由華、池田学、橋本亮太
    • Organizer
      第50回日本神経精神薬理学会年会・第42回日本生物学的精神医学会年会・第4回日本精神薬学会総会・学術集会(NPBPPP合同年会)
    • Related Report
      2020 Annual Research Report
  • [Presentation] 治療の指針となる診断法の開発研究の真のゴールとその道のり2020

    • Author(s)
      橋本亮太、松本純弥、長谷川尚美、三浦健一郎
    • Organizer
      第50回日本神経精神薬理学会年会・第42回日本生物学的精神医学会年会・第4回日本精神薬学会総会・学術集会(NPBPPP合同年会)
    • Related Report
      2020 Annual Research Report
  • [Presentation] 眼球運動特徴による自己組織化マップを用いた統合失調症の層別化2020

    • Author(s)
      三浦健一郎、松本純弥、長谷川尚美、藤本美智子、山森英長、安田由華、橋本亮太
    • Organizer
      第50回日本神経精神薬理学会年会・第42回日本生物学的精神医学会年会・第4回日本精神薬学会総会・学術集会(NPBPPP合同年会)
    • Related Report
      2020 Annual Research Report
  • [Presentation] 統合失調症のbiotypeである認知機能障害と大脳白質統合性の関連2020

    • Author(s)
      松本純弥、三浦健一郎、坂元竜馬、福永雅喜、越山太輔、根本清貴、岡田直大、森田健太郎、大井一高、長谷川尚美、藤本美智子、山森英長、安田由華、笠井清登、渡邉嘉之、橋本亮太
    • Organizer
      第50回日本神経精神薬理学会年会・第42回日本生物学的精神医学会年会・第4回日本精神薬学会総会・学術集会(NPBPPP合同年会)
    • Related Report
      2020 Annual Research Report
  • [Presentation] 統合失調症患者と健常被験者における拡散テンソル画像を用いた大脳白質微細構造と認知機能2020

    • Author(s)
      松本純弥、三浦健一郎、福永雅喜、越山太輔、根本清貴、大井一高、岡田直大、長谷川尚美、山森英長、安田由華、藤本美智子、鬼塚俊明、高橋努、尾崎紀夫、渡邉嘉之、橋本亮太
    • Organizer
      第50回日本神経精神薬理学会年会・第42回日本生物学的精神医学会年会・第4回日本精神薬学会総会・学術集会(NPBPPP合同年会)
    • Related Report
      2020 Annual Research Report
  • [Presentation] 暴力の既往のある統合失調症罹患者の、認知機能、精神病理、心理社会的背景の特徴、2020

    • Author(s)
      柏木宏子、三浦健一郎、松本純弥、坂元竜馬、竹田康二、山田悠至、藤本美智子、安田由華、山森英長、池田学、平林直次、橋本亮太
    • Organizer
      第50回日本神経精神薬理学会年会・第42回日本生物学的精神医学会年会・第4回日本精神薬学会総会・学術集会(NPBPPP合同年会)
    • Related Report
      2020 Annual Research Report
  • [Presentation] 精神疾患の病態解明研究のトレンドウォッチ:ビッグデータと仮説検証研究2020

    • Author(s)
      橋本亮太
    • Organizer
      第43回日本神経科学大会
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] フリービューイング時のマカクサルの視覚探索行動:ヒトとの比較2020

    • Author(s)
      三浦健一郎、吉田正俊、藤本美智子、山森英長、安田由華、長谷川尚美、松本純弥、橋本亮太、竹村文
    • Organizer
      第43回日本神経科学大会
    • Related Report
      2020 Annual Research Report
  • [Presentation] 精神疾患の克服とその障害の支援2020

    • Author(s)
      橋本亮太
    • Organizer
      NCNP EDICS/精神科共催セミナー
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] Manipulation of primate neural networks by means of modified viral vectors.2019

    • Author(s)
      Inoue K
    • Organizer
      Molecular Genetic Tools for the Study of Neural Circuits summer school
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 霊長類における光遺伝学を利用した神経回路操作2019

    • Author(s)
      井上 謙一
    • Organizer
      日本動物学会第90回大阪大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] マカクザルのミラーシステムおよびメンタライジングシステムにおける自他行動モニタリング中の神経活動およびその相互作用2019

    • Author(s)
      二宮太平、則武厚、磯田昌岐
    • Organizer
      第42回日本神経科学大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Social reward monitoring and valuation in corticosubcortical networks of the macaque2019

    • Author(s)
      則武厚、二宮太平、磯田昌岐
    • Organizer
      The 9th Okazaki / Tuebingen / Beijing Joint Symposium
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 統合失調症の眼球運動研究2019

    • Author(s)
      森田健太郎、三浦健一郎、藤本美智子、宍戸恵美子、椎野智子、高橋潤一、山森英長、工藤紀子、畦地裕統、平野羊嗣、越山大輔、岡田直大、鬼塚俊明、尾崎紀夫、笠井清登、池田学、橋本亮太
    • Organizer
      第14回日本統合失調症学会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 精神疾患のバイオタイプによる診断・治療法の開発2019

    • Author(s)
      橋本亮太
    • Organizer
      第17回IGC第13回COCORO合同会議
    • Related Report
      2019 Annual Research Report
  • [Presentation] 生来の白血球数・顆粒球数とクロザピン誘発性顆粒球減少症:Mendelian Randomization解析2019

    • Author(s)
      島崎愛夕、齋藤竹生、大河内智、谷口賢、二宮光平、橋本亮太、池田匡志、岩田仲生、CPC-J(Clozapine Pharmacogenomics Consortium of Japan:日本クロザピン薬理ゲノム学コンソーシアム)
    • Organizer
      第115回日本精神神経学会学術総会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Clozapine により好酸球増加症が生じたが継続投与が可能であった治療抵抗性統合失調症の一例2019

    • Author(s)
      藤本美智子、山森英長、安田由華、加藤恒、金倉譲、岩瀬真生、池田学、橋本亮太
    • Organizer
      第115回日本精神神経学会学術総会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 統合失調症におけるバイオマーカーとしての眼球運動スコアの臨床的意義2019

    • Author(s)
      藤本美智子、三浦健一郎、森田健太郎、工藤紀子、畦地裕統、山森英長、安田由華、池田学、橋本亮太
    • Organizer
      第41回日本生物学的精神医学会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 精神疾患における認知機能障害と社会活動時間との関連2019

    • Author(s)
      宇野洋太、工藤紀子、山森英長、藤野陽生、住吉チカ、安田由華、藤本美智子、勝元榮一、佐田あゆ美、畦地裕統、椎野智子、嶋田貴充、片岡譲、高橋潤一、森田健太郎、香月あすか、山本真江里、岡久祐子、肥田道彦、平野羊嗣、牧之段学、中瀧理仁、橋本直樹、大井一高、高橋努、根本清貴、岸本年史、鈴木道雄、住吉太幹、橋本亮太
    • Organizer
      第41回日本生物学的精神医学会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 自閉スペクトラム症と統合失調症の眼球運動特性の検討2019

    • Author(s)
      椎野智子、三浦健一郎、藤本美智子、工藤紀子、山森英長、安田由華、池田学、橋本亮太
    • Organizer
      第41回日本生物学的精神医学会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 統合失調症における眼球運動・認知機能・社会機能の縦断的関係性の検討2019

    • Author(s)
      森田健太郎、三浦健一郎、藤本美智子、山森英長、安田由華、工藤紀子、畦地裕統、岡田直大、越山太輔、池田学、笠井清登、橋本亮太
    • Organizer
      第41回日本生物学的精神医学会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 大うつ病性障害における眼球運動異常2019

    • Author(s)
      高橋潤一、三浦健一郎、森田健太郎、藤本美智子、山森英長、安田由華、工藤紀子、宍戸恵美子、岡崎康輔、椎野智子、笠井清登、平野羊嗣、橋本亮太、鬼塚俊明
    • Organizer
      第41回日本生物学的精神医学会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 大うつ病性障害における眼球運動2019

    • Author(s)
      高橋潤一、三浦健一郎、森田健太郎、藤本美智子、山森英長、安田由華、工藤紀子、宍戸恵美子、岡崎康輔、椎野智子、笠井清登、平野羊嗣、橋本亮太、鬼塚俊明
    • Organizer
      第16回日本うつ病学会総会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 気分障害のバイオマーカーとしての血清中グリア細胞株由来神経栄養因子(GDNF)に関する多施設共同研究2019

    • Author(s)
      井出本啓太、新津富央、畑発達記、小田靖典、木村敦史、橋本佐、亀野陽亮、蓬莱政、山森英長、戸田重誠、菱本明豊、橋本亮太、中込和幸、橋本謙二、伊豫雅臣
    • Organizer
      第16回日本うつ病学会総会
    • Related Report
      2019 Annual Research Report
  • [Presentation] ASD-related de novo POGZ mutations disrupt cortical neuronal differentiation.2019

    • Author(s)
      Matsumura K, Seiriki K, Nagase M, Ayabe S, Yamada I, Furuse T, Yamamoto K, Kitagawa K, Iguchi T, Sato M, Yamaguchi S, Tamura M, Wakana S, Yoshi A, Watabe AM, Okano H, Takuma K, Hashimoto R, Hashimoto H, Nakazawa T.
    • Organizer
      第42回日本神経科学大会・第62回日本神経化学会大会(Neuro2019)
    • Related Report
      2019 Annual Research Report
  • [Presentation] Pathological analysis of neurons from iPS cells derived from patients with schizophrenia in a multiple family.2019

    • Author(s)
      Yamamoto K, Kuriu T, Nakazawa T, Matsumura K, Nayasu K, Baba M, Yamamori H, Yasuda Y, Fujimoto M, Tsurusaki Y, Matsumoto N, Takuma K, Hashimoto R, Hashimoto H.
    • Organizer
      第42回日本神経科学大会・第62回日本神経化学会大会(Neuro2019)
    • Related Report
      2019 Annual Research Report
  • [Presentation] Comparison of eye movement in Autism Spectrum Disorder and Schizophrenia.2019

    • Author(s)
      Shiino T, Miura K, Fujimoto M, Kudo N, Yamamori H, Yasuda Y, Ikeda M, Hashimoto R
    • Organizer
      第42回日本神経科学大会・第62回日本神経化学会大会(Neuro2019)
    • Related Report
      2019 Annual Research Report
  • [Presentation] 精神疾患病態研究におけるDSMとRDoCの功罪2019

    • Author(s)
      橋本亮太
    • Organizer
      第6回NCNPメディア塾
    • Related Report
      2019 Annual Research Report
  • [Presentation] Multi-site Harmonization of Resting-state functional connectivity MRI data improves classification of major depressive disorder.2019

    • Author(s)
      Takamura T, Nakamura T, Yoshinaga K, Ogata Y, Ozaki N, Kasai K, Hashimoto R, Hanakawa T.
    • Organizer
      第3回ヒト脳イメージング研究会
    • Related Report
      2019 Annual Research Report
  • [Presentation] DTIによる大脳白質の髄鞘化/成熟性の評価と社会機能の指標としての労働時間との関連2019

    • Author(s)
      松本純弥、福永雅喜、根本清貴、越山大輔、三浦健一郎、岡田直大、森田健太郎、山森英長、宇野洋太、安田由華、藤本美智子、工藤紀子、畦地裕統、渡邉嘉之、笠井清登、橋本亮太
    • Organizer
      第3回ヒト脳イメージング研究会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 統合失調症でみられる眼球運動特徴の神経基盤の検討2019

    • Author(s)
      森田健太郎、三浦健一郎、藤本美智子、山森英長、安田由華、工藤紀子、畦地裕統、岡田直大、越山大輔、椎野智子、福永雅喜、渡邉嘉之、笠井清登、池田学、橋本亮太
    • Organizer
      第3回ヒト脳イメージング研究会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 統合失調症における眼球運動特性の診断補助的指標としての再現性2019

    • Author(s)
      藤本美智子、三浦健一郎、森田健太郎、工藤紀子、畦地裕統、山森英長、安田由華、池田学、橋本亮太
    • Organizer
      第39回日本精神科診断学会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 精神科診断が乗り越えるべきもの:未来への展望2019

    • Author(s)
      橋本亮太
    • Organizer
      第39回日本精神科診断学会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] The comparison of q-space myelin map, fractional anisotropy and apparent diffusion coefficient values between normal young and old ages2019

    • Author(s)
      Shixing B, Watanabe Y, Tomiyama N, Takahashi H, Hashimoto R, Hata J.
    • Organizer
      第47回日本磁気共鳴医学会大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 眼球運動による精神疾患のバイオタイプ分類は可能か2019

    • Author(s)
      森田健太郎、三浦健一郎、藤本美智子、宍戸恵美子、高橋潤一、山森英長、安田由華、工藤紀子、畦地裕統、平野羊嗣、越山太輔、岡田直大、鬼塚俊明、尾崎紀夫、笠井清登、池田学、橋本亮太
    • Organizer
      第49回日本神経精神薬理学会・第29回日本臨床精神神経薬理学会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 精神疾患のバイオタイプ概説2019

    • Author(s)
      橋本亮太、宇野洋太、松本純弥、住吉チカ、森田健太郎、越山太輔、岡田直大、藤野陽生、大井一高、藤本美智子、安田由華、山森英長、住吉太幹、根本清貴、福永雅喜、三浦健一郎
    • Organizer
      第49回日本神経精神薬理学会・第29回日本臨床精神神経薬理学会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 大脳白質の成熟性と社会機能の指標である労働時間との関連2019

    • Author(s)
      松本純弥、福永雅喜、根本清貴、越山太輔、三浦健一郎、宇野洋太、岡田直大、森田健太郎、山森英長、安田由華、藤本美智子、工藤紀子、畦地裕統、笠井清登、渡邉嘉之、橋本亮太
    • Organizer
      第49回日本神経精神薬理学会年会
    • Related Report
      2019 Annual Research Report
  • [Presentation] カテゴリ流暢性課題を利用した統合失調症患者の高次認知機能の評価:最近の研究動向2019

    • Author(s)
      住吉チカ、松井三枝、倉知正佳、橋本亮太、吉村直記、住吉太幹
    • Organizer
      第19回精神疾患と認知機能研究会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Clozapine投与中の治療抵抗性統合失調症患者における簡易認知機能検査の実践2019

    • Author(s)
      藤本美智子、山森英長、三浦健一郎、安田由華、工藤紀子、畦地裕統、住吉チカ、藤野陽生、住吉太幹、池田学、橋本亮太、
    • Organizer
      第19回精神疾患と認知機能研究会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 多施設共同研究体制の構築2019

    • Author(s)
      橋本亮太
    • Organizer
      第18回IGC第14回COCORO合同会議
    • Related Report
      2019 Annual Research Report
  • [Presentation] 精神疾患のバイオタイプによる診断・治療法の開発2019

    • Author(s)
      橋本亮太
    • Organizer
      第18回IGC第14回COCORO合同会議
    • Related Report
      2019 Annual Research Report
  • [Presentation] Association between Work Status and Subjective Aspects of Recovery in Patients with Schizophrenia: A longitudinal study.2019

    • Author(s)
      Sumiyoshi C, Ohi K, Fujino H, Yamamori H, Kudo N, Azechi H, Fujimoto M, Yasuda Y, Sumiyoshi T, Hashimoto R.
    • Organizer
      SIRS(Schizophrenia International Research Society)
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Clozapine-induced seizure complicated with vertebral fracture, leg paralysis and pulmonary embolism in a patient with treatment-resistant schizophrenia.2019

    • Author(s)
      Fujimoto M, Taomoto D, Katakami S, Omi T, Hashimoto R, Yamamori H, Yasuda Y, Makino T, Yoshikawa H, Iwase M, Ikeda M.
    • Organizer
      AsCNP (6th Congress of Asian College of Neuropsychopharmacology)
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] International neuroimaging big data collaborations:ENIGMA and COCORO2019

    • Author(s)
      Hashimoto R
    • Organizer
      AsCNP (6th Congress of Asian College of Neuropsychopharmacology)
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Book] 眼球運動の定量的分析とその精神医学への応用、月刊 細胞2022

    • Author(s)
      三浦健一郎,松本純弥,長谷川尚美,橋本亮太
    • Total Pages
      4
    • Publisher
      ニューサイエンス社
    • Related Report
      2021 Annual Research Report
  • [Book] 統合失調症・双極性障害に共通する大脳白質の微細構造変化、精神科臨床Legato2021

    • Author(s)
      越山太輔、福永雅喜、笠井清登、橋本亮太
    • Total Pages
      4
    • Publisher
      メディカルレビュー社
    • Related Report
      2021 Annual Research Report
  • [Book] 今後の精神医学研究を語る, 精神科臨床Legato2021

    • Author(s)
      橋本亮太、神庭重信、岩田仲生、尾崎紀夫、加藤忠史
    • Total Pages
      8
    • Publisher
      メディカルレビュー社
    • Related Report
      2021 Annual Research Report
  • [Book] 統合失調症における認知機能障害と脳画像、特集「統合失調症と気分障害における認知機能障害への対処と治療」、臨床精神医学2021

    • Author(s)
      安田由華、橋本亮太
    • Total Pages
      8
    • Publisher
      アークメディア
    • Related Report
      2021 Annual Research Report
  • [Book] 社会行動、Clinical Neuroscience2020

    • Author(s)
      植松明子、二宮太平、磯田昌岐
    • Total Pages
      4
    • Publisher
      中外医学社
    • Related Report
      2019 Annual Research Report
  • [Book] 他者の報酬が気になる神経機構、Clinical Neuroscience2020

    • Author(s)
      則武厚、二宮太平、磯田昌岐
    • Total Pages
      3
    • Publisher
      中外医学社
    • Related Report
      2019 Annual Research Report
  • [Book] 精神科診断が乗り越えるべきもの:未来への展望、精神科診断学2020

    • Author(s)
      橋本亮太
    • Total Pages
      8
    • Publisher
      日本精神科診断学会
    • Related Report
      2019 Annual Research Report
  • [Book] 精神科医療における標準治療の課題と展望、日本精神科病院協会雑誌2019

    • Author(s)
      橋本亮太
    • Total Pages
      2
    • Publisher
      日本精神科病院協会
    • Related Report
      2019 Annual Research Report
  • [Book] 統合失調症の診療におけるAIの活用、臨床精神医学2019

    • Author(s)
      三浦健一郎、橋本亮太
    • Total Pages
      5
    • Publisher
      アークメディア
    • Related Report
      2019 Annual Research Report
  • [Remarks] 生理学研究所 システム脳科学研究領域 認知行動発達機構研究部門 ホームページ

    • URL

      https://www.nips.ac.jp/dbd/NewSite/index.html

    • Related Report
      2023 Annual Research Report 2022 Annual Research Report 2021 Annual Research Report 2020 Annual Research Report
  • [Remarks] 国立精神・神経医療研究センター 精神保健研究所 精神疾患病態研究部 ホームページ

    • URL

      https://byoutai.ncnp.go.jp/

    • Related Report
      2023 Annual Research Report 2022 Annual Research Report 2021 Annual Research Report 2020 Annual Research Report
  • [Remarks] 筑波大学 医学医療系 生命医科学域 認知行動神経科学研究室 ホームページ

    • URL

      http://www.md.tsukuba.ac.jp/basic-med/cog-neurosci/member.html

    • Related Report
      2023 Annual Research Report 2022 Annual Research Report 2021 Annual Research Report 2020 Annual Research Report
  • [Remarks] 京都大学ヒト行動進化研究センター 統合脳システム分野 ホームページ

    • URL

      http://www.pri.kyoto-u.ac.jp/sections/systems_neuroscience/index.html

    • Related Report
      2023 Annual Research Report
  • [Remarks] 京都大学ヒト行動進化研究センター 高田研究室 ホームページ

    • URL

      https://ehub-kyoto-u.wixsite.com/takada-lab

    • Related Report
      2022 Annual Research Report
  • [Remarks] 京都大学霊長類研究所(現 ヒト行動進化研究センター) 統合脳システム分野 ホームページ

    • URL

      http://www2.ehub.kyoto-u.ac.jp/sections/systems_neuroscience/

    • Related Report
      2021 Annual Research Report
  • [Remarks] 京都大学霊長類研究所 統合脳システム分野 ホームページ

    • URL

      http://www.pri.kyoto-u.ac.jp/sections/systems_neuroscience/index.html

    • Related Report
      2020 Annual Research Report 2019 Annual Research Report
  • [Remarks] 橋本亮太 精神・神経・筋難病の克服を目指した研究開発、国立研究開発法人イノベーション戦略会議

    • URL

      https://www8.cao.go.jp/cstp/stmain/5kokken.html

    • Related Report
      2020 Annual Research Report
  • [Remarks] 生理学研究所システム 脳科学研究領域 認知行動発達機構研究部門 ホームページ

    • URL

      https://www.nips.ac.jp/dbd/NewSite/index.html#home

    • Related Report
      2019 Annual Research Report
  • [Remarks] 国立精神・神経医療研究センター 精神保健研究所 精神疾患病態研究部 ホームページ

    • URL

      https://byoutai.ncnp.go.jp/

    • Related Report
      2019 Annual Research Report
  • [Remarks] 筑波大学 医学医療系 生命医科学域 認知行動神経科学研究室 ホームページ

    • URL

      http://www.md.tsukuba.ac.jp/basic-med/cog-neurosci/member.html

    • Related Report
      2019 Annual Research Report
  • [Funded Workshop] 京都大学ヒト行動進化研究センター国際脳科学シンポジウム2024

    • Related Report
      2023 Annual Research Report

URL: 

Published: 2019-05-29   Modified: 2025-02-04  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi