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Early detection and support of autistic spectrum disorder focusing on sensory processing characteristics

Research Project

Project/Area Number 19K02925
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 09060:Special needs education-related
Research InstitutionMeiji Gakuin University (2022)
Hirosaki University (2019-2021)

Principal Investigator

Adachi Masaki  明治学院大学, 心理学部, 准教授 (50637329)

Co-Investigator(Kenkyū-buntansha) 萩原 拓  北海道教育大学, 教育学部, 教授 (00431388)
斉藤 まなぶ  弘前大学, 医学研究科, 准教授 (40568846)
高橋 芳雄  弘前大学, 保健学研究科, 准教授 (70760891)
中村 和彦  弘前大学, 医学研究科, 教授 (80263911)
Project Period (FY) 2019-04-01 – 2023-03-31
Project Status Completed (Fiscal Year 2022)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2021: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2020: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2019: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywords自閉スペクトラム症 / スクリーニング / 感覚処理 / 感覚プロファイル / 早期発見 / 3歳児健診 / SRS-2 / SSP / 3歳児 / 5歳児 / 感覚処理特性 / 発達障害
Outline of Research at the Start

コミュニティベースのサンプル(N=2,400)を対象に、
1) 3歳で得られた感覚処理特性の指標が横断的・縦断的にASDの診断を予測するか否か、
2) 3歳で得られた感覚処理の指標が5歳時点のASDの症状や生活適応とどのように関連するかを明らかにする。
これらの知見から、
3) 早期介入の指標となる感覚処理の特徴を提案するとともに、
4) その特徴に応じた介入方法の指針について提案することを目的に研究を行う。

Outline of Final Research Achievements

With the goal of examining sensory processing patterns that promote early detection of ASD, Latent Class Analysis was performed on data from a shortened version of the sensory profile (SSP) of 1375 3-year-old children.
The results of the analysis suggested a division into two groups: one group (Class 1), representing 82.8% of the community, exhibiting average SSP scores, and a second group (Class 2), in which all SSP subscale scores were higher than Class 1. Logistic regression analysis showed that Class 2 significantly predicted the SRS-2 cutoff classification.
These results suggest that patterns of sensory processing may contribute to early detection of ASD in community-based screening.

Academic Significance and Societal Importance of the Research Achievements

ASDの近年の研究では、乳幼児期から感覚処理の特徴に注目することによって早期発見が促進され、社会的予後の向上に役立つ可能性が示唆されているが、未診断のASDが含まれているコミュニティベースのサンプルを用いて、実際に早期発見が可能か否かを検証した研究は国内外においてない。
本研究では、診断の予測までは至らなかったものの、コミュニティ・サンプルにおいて感覚処理の非定型的なパターンを示す一群がコミュニティの18%程度存在すること、そのグループが自閉症のスクリーニング尺度のカットオフ分類を有意に予測する一群であることを明らかにしたことは、今後の本領域の発展に一定の貢献があったものと考える。

Report

(5 results)
  • 2022 Annual Research Report   Final Research Report ( PDF )
  • 2021 Research-status Report
  • 2020 Research-status Report
  • 2019 Research-status Report
  • Research Products

    (34 results)

All 2023 2022 2021 2020 2019 Other

All Int'l Joint Research (5 results) Journal Article (8 results) (of which Int'l Joint Research: 8 results,  Peer Reviewed: 8 results,  Open Access: 8 results) Presentation (14 results) (of which Int'l Joint Research: 5 results) Remarks (7 results)

  • [Int'l Joint Research] カリフォルニア大学サンフランシスコ校(UCSF)(米国)

    • Related Report
      2022 Annual Research Report
  • [Int'l Joint Research] カリフォルニア大学サンフランシスコ校(米国)

    • Related Report
      2021 Research-status Report
  • [Int'l Joint Research] University of California San Francisco(米国)

    • Related Report
      2020 Research-status Report
  • [Int'l Joint Research] University of California San Francisco(米国)

    • Related Report
      2019 Research-status Report
  • [Int'l Joint Research] 上海交通大学(中国)

    • Related Report
      2019 Research-status Report
  • [Journal Article] Trajectories of emotional and behavioral problems in school-age children with coordination difficulties and their relationships to ASD/ADHD traits2023

    • Author(s)
      Mikami Misaki、Hirota Tomoya、Adachi Masaki、Takahashi Michio、Nishimura Tomoko、Saito Manabu、Nakamura Kazuhiko、Yamada Junko
    • Journal Title

      Research in Developmental Disabilities

      Volume: 133 Pages: 104394-104394

    • DOI

      10.1016/j.ridd.2022.104394

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] School Social Capital Mediates Associations Between ASD Traits and Depression Among Adolescents in General Population2022

    • Author(s)
      Mori Hiroyuki、Hirota Tomoya、Monden Rei、Takahashi Michio、Adachi Masaki、Nakamura Kazuhiko
    • Journal Title

      Journal of Autism and Developmental Disorders

      Volume: - Issue: 10 Pages: 1-10

    • DOI

      10.1007/s10803-022-05687-9

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Longitudinal association between addictive internet use and depression in early adolescents over a 2-year period: A study using a random intercept cross-lagged model2022

    • Author(s)
      Takahashi Michio、Adachi Masaki、Hirota Tomoya、Nishimura Tomoko、Shinkawa Hiroki、Mori Hiroyuki、Nakamura Kazuhiko
    • Journal Title

      Computers in Human Behavior

      Volume: 132 Pages: 107251-107251

    • DOI

      10.1016/j.chb.2022.107251

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Interformat Reliability of Web-Based Parent-Rated Questionnaires for Assessing Neurodevelopmental Disorders Among Preschoolers: Cross-sectional Community Study2021

    • Author(s)
      Tanaka Masanori、Saito Manabu、Takahashi Michio、Adachi Masaki、Nakamura Kazuhiko
    • Journal Title

      JMIR Pediatrics and Parenting

      Volume: 4 Issue: 1 Pages: e20172-e20172

    • DOI

      10.2196/20172

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Prevalence and cumulative incidence of autism spectrum disorders and the patterns of co-occurring neurodevelopmental disorders in a total population sample of 5-year-old children2020

    • Author(s)
      Saito Manabu、Hirota Tomoya、Sakamoto Yui、Adachi Masaki、Takahashi Michio、Osato-Kaneda Ayako、Kim Young Shin、Leventhal Bennett、Shui Amy、Kato Sumi、Nakamura Kazuhiko
    • Journal Title

      Molecular Autism

      Volume: 11 Issue: 1 Pages: 35-35

    • DOI

      10.1186/s13229-020-00342-5

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Utilization of the Maternal and Child Health Handbook in Early Identification of Autism Spectrum Disorder and Other Neurodevelopmental Disorders2020

    • Author(s)
      Hirota Tomoya、Bishop Somer、Adachi Masaki、Shui Amy、Takahashi Michio、Mori Hiroyuki、Nakamura Kazuhiko
    • Journal Title

      Autism Research

      Volume: 14 Issue: 3 Pages: 551-559

    • DOI

      10.1002/aur.2442

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Atypical Sensory Processing Profiles and Their Associations With Motor Problems In Preschoolers With Developmental Coordination Disorder2020

    • Author(s)
      Mikami Misaki、Hirota Tomoya、Takahashi Michio、Adachi Masaki、Saito Manabu、Koeda Shuhei、Yoshida Kazutaka、Sakamoto Yui、Kato Sumi、Nakamura Kazuhiko、Yamada Junko
    • Journal Title

      Child Psychiatry & Human Development

      Volume: 52 Issue: 2 Pages: 311-320

    • DOI

      10.1007/s10578-020-01013-5

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Association between Sleep Disturbances and Emotional/Behavioral Problems in Chinese and Japanese Preschoolers.2020

    • Author(s)
      Wang G, Takahashi M, Wu R, Liu Z, Adachi M, Saito M, Nakamura, K, Jiang F.
    • Journal Title

      Behavioral Sleep Medicine

      Volume: 18(3) Issue: 3 Pages: 420-431

    • DOI

      10.1080/15402002.2019.1605995

    • Related Report
      2019 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Presentation] Early detection of ASD by community-based screening focusing on sensory processing characteristics2021

    • Author(s)
      Adachi M, Takahashi M, Hirota T, Mikami M, Shinkawa H, Mori H, Mikami T, Saito M, Hagiwara T, Nakamura K.
    • Organizer
      International Society for Autism Research (INSAR) 2019 Annual Meeting
    • Related Report
      2021 Research-status Report
    • Int'l Joint Research
  • [Presentation] Development of a Screening Algorithm of Neurodevelopmental Disorders for 5-Year-Old Children Toward Web Survey Systemization2020

    • Author(s)
      A. Terui, M. Saito, A. Osato, M. Tanaka, N. Takayanagi, M. Adachi, M. Wakuta, Y. Sakamoto, H. Mori, K. Yoshida, Y. Matsubara, T. Mikami, M. Takahashi, K. Nakamura and Y. Yamamura,
    • Organizer
      The International Society for Autism Research (INSAR) 2020 Annual Meeting
    • Related Report
      2020 Research-status Report
    • Int'l Joint Research
  • [Presentation] Utilization of the Maternal and Child Health Handbook in Early Identification of Autism Spectrum Disorder and Other Neurodevelopmental Disorders2020

    • Author(s)
      T Hirota, S. Bishop, M. Adachi, M. Takahashi, H. Mori, A. M. Shui and K. Nakamura
    • Organizer
      The International Society for Autism Research (INSAR) 2020 Annual Meeting
    • Related Report
      2020 Research-status Report
    • Int'l Joint Research
  • [Presentation] 5歳児発達健診 Web スクリーニングシステム(ここあぽ)の完成2020

    • Author(s)
      斉藤 まなぶ、田中 勝則 、山村 靖彦 、和久田 学、大里 絢子、足立 匡基、三上 珠希 、 坂本 由唯 、照井 藍 、森 裕幸、新川 広樹 、高橋 芳雄、栗林 理人、中村 和彦
    • Organizer
      第116回日本精神神経学会学術集会
    • Related Report
      2020 Research-status Report
  • [Presentation] 5歳児発達健診でのWebスクリーニングシステムの活用2020

    • Author(s)
      斉藤まなぶ、田中勝則、大里絢子、足立匡基、坂本由唯、三上珠希、照井藍、鈴木裕幸、新川広樹、高橋芳雄、中村和彦
    • Organizer
      第62回日本小児神経学会学術集会
    • Related Report
      2020 Research-status Report
  • [Presentation] 3歳児健診における簡便かつ鋭敏な神経発達症のスクリーニング法の探索2020

    • Author(s)
      大里 絢子, 斉藤 まなぶ, 坂本 由唯, 三上 珠希, 足立 匡基, 中村 和彦
    • Organizer
      第61回日本児童青年精神医学会総会
    • Related Report
      2020 Research-status Report
  • [Presentation] 5歳児発達健診でのwebスクリーニングシステムの活用2020

    • Author(s)
      照井 藍, 斉藤 まなぶ, 田中 勝則, 大里 絢子, 足立 匡基, 坂本 由唯, 三上 珠希, 栗林 理人, 中村 和彦
    • Organizer
      第61回日本児童青年精神医学会総会
    • Related Report
      2020 Research-status Report
  • [Presentation] 地域における5歳の自閉スペクトラム症の疫学調査 調整有病率と累積発生率2020

    • Author(s)
      斉藤 まなぶ, 坂本 由唯, 足立 匡基, 高橋 芳雄, 大里 絢子, 三上 珠希, 照井 藍, 栗林 理人, 中村 和彦
    • Organizer
      第61回日本児童青年精神医学会総会
    • Related Report
      2020 Research-status Report
  • [Presentation] Comorbid Rate of Other Neurodevelopmental Disorder with Autism Spectrum Disorder in a Total Population Sample of 5-Years-Old Children.2019

    • Author(s)
      A. Terui , M. Saito, T. Hirota, Y. Sakamoto, Y. Matsubara, M. Adachi, M. Takahashi, A. Osato, K. Nakamura
    • Organizer
      International Society for Autism Research(INSAR) 2019 ANNUAL MEETING, May 1-4, Montreal,Canada
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Presentation] Cumulative Incidence of Autism Spectrum Disorders in a Total Population Sample of 5-Year-Old Children2019

    • Author(s)
      T. Hirota, M. Saito, Y. Sakamoto, M. Adachi, M. Takahashi, A. Osato, Y. S. Kim, B. L. Leventhal, A. M. Shui, S. Kato , K. Nakamura
    • Organizer
      International Society for Autism Research(INSAR) 2019 ANNUAL MEETING, May 1-4, Montreal,Canada
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Presentation] Suicidality in Autism Spectrum Disorder Comorbid with ADHD Symptoms in a Non-Clinical School-Aged Population2019

    • Author(s)
      M. Adachi, M. Takahashi, T. Hirota, N. Takayanagi, S. Yasuda, Y. Sakamoto, M. Saito, K. Nakamura
    • Organizer
      International Society for Autism Research(INSAR) 2019 ANNUAL MEETING, May 1-4, Montreal,Canada
    • Related Report
      2019 Research-status Report
  • [Presentation] 子どもの個のメンタルヘルスの追跡2019

    • Author(s)
      足立匡基・西村倫子・浦尾悠子・藤岡徹・明翫光宜・田中早苗・和久田学・河合優年・片山泰一・中村和彦
    • Organizer
      第60回日本児童青年精神医学会総会
    • Related Report
      2019 Research-status Report
  • [Presentation] A市における3歳児健診への発達スクリーニング導入について2019

    • Author(s)
      大里絢子・三上珠希・斉藤まなぶ・吉田和貴・栗林理人・足立匡基・中村和彦
    • Organizer
      第60回日本児童青年精神医学会総会
    • Related Report
      2019 Research-status Report
  • [Presentation] 神経発達症スクリーニングツールのweb版および紙筆版との等質性の検証2019

    • Author(s)
      田中勝則・斉藤まなぶ・足立匡基・髙橋芳雄・中村和彦
    • Organizer
      第60回日本児童青年精神医学会総会
    • Related Report
      2019 Research-status Report
  • [Remarks] Researchmap

    • URL

      https://researchmap.jp/-------/?lang=ja

    • Related Report
      2021 Research-status Report
  • [Remarks] Researchgate

    • URL

      https://www.researchgate.net/profile/Masaki-Adachi-2

    • Related Report
      2021 Research-status Report
  • [Remarks] ORCID

    • URL

      https://orcid.org/0000-0003-3115-9455

    • Related Report
      2021 Research-status Report
  • [Remarks] Research Gate

    • URL

      https://www.researchgate.net/profile/Masaki-Adachi-2

    • Related Report
      2020 Research-status Report
  • [Remarks] Researchmap

    • URL

      https://researchmap.jp/-------

    • Related Report
      2020 Research-status Report 2019 Research-status Report
  • [Remarks] 弘前大学研究者総覧

    • URL

      http://hue2.jm.hirosaki-u.ac.jp/html/200001065_ja.html

    • Related Report
      2020 Research-status Report 2019 Research-status Report
  • [Remarks] 弘前大学大学院医学研究科附属子どものこころの発達研究センター

    • URL

      http://www.med.hirosaki-u.ac.jp/~kodomono/

    • Related Report
      2020 Research-status Report 2019 Research-status Report

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Published: 2019-04-18   Modified: 2024-01-30  

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